FIG. 1. N-hydroxy-PhIP O-acetyltransferase activities in rapid and slow acetylator congenic hamster tissue cytosols. Data represent mean ± SE for three to eight individual hamsters. Solid bars represent homozygous rapid acetylators; open bars represent homozygous slow acetylators. *N-hydroxy-PhIP O-acetyltransferase activity was significantly higher (p < 0.05) in rapid versus slow acetylator congenic hamsters. Abbreviations: LV, liver; SI, small intestine; CE, cecum; AC, ascending colon; TC, transverse colon; DC, descending colon; RT, rectum; PS, pancreas; PT, prostate; HT, heart; ST, stomach; ES, esophagus.