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© 1982 Oxford University Press

research-article

Effects of Lifelong Administration of ß-Phenylisopropylhydrazine Hydrochloride and Thiocarbamylhydrazine in Mice

BELA TOTH

The Eppley Institute for Research in Cancer and Allied Diseases, University of Nebraska Medical Center Omaha, Nebraska 68105, U.S.A.

Effects of Lifelong Administration of ß-Phenylisopropyl-hydrazine hydrochloride and thiocarbamylhydrazine in mice. Toth, B. (1982). Fundam. Appl. Toxicol. 2:173-176. ß-Phenylisopropylhydrazine hydrochloride and thiocarbamylhydrazine were separately administered as 0.0312 and 0.0156% solutions in drinking water for life to randomly bred Swiss mice. The consumption of the chemicals resulted in no detectable tumorigenic effects in the treated animals, and it is therefore concluded that these compounds are apparently noncarcinogenic under the present experimental conditions.


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