Skip Navigation

This Article
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Alert me to new issues of the journal
Right arrow Add to My Personal Archive
Right arrow Download to citation manager
Right arrowRequest Permissions
Right arrow Disclaimer
Google Scholar
Right arrow Articles by KELLER, J. C.
Right arrow Articles by KAMINSKI, E. J.
Right arrow Search for Related Content
PubMed
Right arrow Articles by KELLER, J. C.
Right arrow Articles by KAMINSKI, E. J.
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us  
What's this?

© 1984 Oxford University Press

research-article

Toxic Effects of Cu Implants on Liver1

JOHN C. KELLER2, and EDWARD J. KAMINSKI

Departments of Biological Materials and Pathology, Northwestern University Chicago, Illinois 60611

Toxic Effects of Cu Implants on liver. KELLER, J. C, AND KAMINSKI E. J. (1984). Fundam. Appl. Toxicol. 4, 778–783. In an effort to identify possible systemic effects due to dissolution of Cu from the experimental use of dental amalgam specimens of pure Cu and several dental amalgams containing various concentrations of Cu were implanted into the peritoneal cavity of rats for 4 weeks. Concentrations of Cu in the liver varied from 33.3 to 156.2 µCu/dry g of liver tissue after implantation of the Cu-containing amalgams. Histopathological changes in the liver confirmed the presence of Cu within the tysosomes of hepatocytes. The histopathological and chemical changes in the liver after implantation indicated the need for subsequent investigations of long-term systemic toxicity to the use of Cu-containing implants


Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us    What's this?




Disclaimer: Please note that abstracts for content published before 1996 were created through digital scanning and may therefore not exactly replicate the text of the original print issues. All efforts have been made to ensure accuracy, but the Publisher will not be held responsible for any remaining inaccuracies. If you require any further clarification, please contact our Customer Services Department.