© 1985 Oxford University Press
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Clearance from the Respiratory Tract1
Institute of Environmental Medicine, New York University Medical Center 550 First Avenue, New York, New York 10016
Clearance from the Respiratory Tract. SCHLESINGER, R. B. (1985). Fundam. Appl. Toxicol. 5, 435450. Clearance is an essential component of the defense system of the respiratory tract. Alterations in the clearance of insoluble particles have been shown to provide a sensitive indicator of response due to exposure to various inhaled materials. This paper reviews clearance mechanisms, the significance of clearance changes, and the methodology used to assess them