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ToxSci Advance Access originally published online on May 9, 2006
Toxicological Sciences 2006 92(1):23-32; doi:10.1093/toxsci/kfj211
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© The Author 2006. Published by Oxford University Press on behalf of the Society of Toxicology. All rights reserved. For Permissions, please email: journals.permissions@oxfordjournals.org

FORUM

Research Strategies for Safety Evaluation of Nanomaterials, Part VIII: International Efforts to Develop Risk-Based Safety Evaluations for Nanomaterials

Karluss Thomas*,1, Pilar Aguar{dagger}, Hajime Kawasaki{ddagger}, Jeff Morris§, Junko Nakanishi{ddagger} and Nora Savage§

* ILSI Health and Environmental Sciences Institute, Washington, District of Columbia 20005; {dagger} Nanosciences and Technologies, Directorate-General for Research, European Commission, Brussels, Belgium; {ddagger} Research Center for Chemical Risk Management, National Institute of Advanced Industrial Science and Technology, Tsukuba, Ibaraki 305-8569, Japan; and § Office of Research and Development, U.S. Environmental Protection Agency, Washington, District of Columbia 20460

Received February 23, 2006; accepted April 19, 2006

The use of nanotechnology in consumer and industrial applications will likely have a profound impact on a number of products from a variety of industrial sectors. Nanomaterials exhibit unique physical/chemical properties and impart enhancements to engineered materials, including better magnetic properties, improved electrical activity, and increased optical properties. The United States, Europe, and Japan have each initiated comprehensive programs to promote and expand the utility of nanotechnology for commercial applications. An important component of these programs is the development of reliable risk and safety evaluations for these materials to ensure their safety for human health and the environment. The scope of each of these programs includes efforts to assess the hazards posed by nanomaterials in realistic exposure conditions.

Key Words: nanotechnology; nanomaterial risk evaluation; nanoscale material risk assessment.


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