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ToxSci Advance Access published online on February 13, 2006

Toxicological Sciences, doi:10.1093/toxsci/kfj129
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© The Author 2006. Published by Oxford University Press on behalf of the Society of Toxicology. All rights reserved. For Permissions, please email: journals.permissions@oxfordjournals.org
Received November 16, 2005
Accepted February 6, 2006

Forum

Research Strategies for Safety Evaluation of Nanomaterials, Part VII: Evaluating Consumer Exposures to Nanoscale Materials

Treye Thomas 1 *, Karluss Thomas 2, Nakissa Sadrieh 3, Nora Savage 4, Patricia Adair 1, and Robert Bronaugh 5

1 U.S. Consumer Product Safety Commission, 4330 East West Highway, Bethesda, MD. 20814
2 ILSI Health and Environmental Sciences Institute, One Thomas Circle, NW, 9th Floor, Washington, DC 20005
3 U.S. Food and Drug Administration, 5515 Security Lane, Rockville, MD 20852
4 U.S. Environmental Protection Agency, 1200 Pennsylvania Avenue, N.W., Washington, D.C. 20460
5 U.S. Food and Drug Administration, 8301 Muirkirk Road, Laurel, MD 20708

* To whom correspondence should be addressed.
Treye Thomas, E-mail: tthomas{at}cpsc.gov


   Abstract

Considerable media attention has recently been given to novel applications for products that contain nanoscale materials. These products could have utility in several industries that market consumer products, including textiles, sporting equipment, cosmetics, consumer electronics, and household cleaners. Some of the purported benefits of these products include improved performance, convenience, lower cost, as well as other desirable features, when compared to the conventional products that do not contain nanoscale materials. Although there are numerous likely consumer advantages from products containing nanoscale materials, there is very little information available regarding consumer exposure to the nanoscale materials in these products or any associated risks from these exposures. This paper seeks to review a limited subset of products that contain nanoscale materials, assess the available data for evaluating the consumer exposures and potential hazards associated with these products, and discuss the capacity of US regulatory agencies to address the potential risks associated with these products.

Keywords: nanoscale materials; consumer products; regulatory agencies; product safety; exposure assessment.
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