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ToxSci Advance Access originally published online on November 4, 2003
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Toxicological Sciences 76, 247-249 (2003)
Copyright © 2003 by the Society of Toxicology

TOXICOLOGICAL HIGHLIGHT

Endocrine Disruptors and the Obesity Epidemic

Jerrold J. Heindel

Cellular, Organs, and Systems Pathobiology Branch, Division of Extramural Research and Training, National Institute of Environmental Health Sciences, NIH, DHHS, POB 12233, Research Triangle Park, NC 27709

Received October 11, 2003; accepted October 11, 2003

The first 150 words of the full text of this article appear below.

The highlighted article brings together research on the site and mechanism of endocrine-disrupting chemicals that have the potential to have a significant impact on human health and research on obesity, which is known to seriously affect human health. The effect of exposure to endocrine-disrupting chemicals on the initiation or exacerbation of obesity, which may significantly alter the perception of the etiology of obesity and impact intervention and prevention efforts, is an important emerging area needing even further research emphasis.

Obesity is a growing concern worldwide. The prevalence of obesity has risen dramatically in developed countries over the past 2 to 3 decades (Oken and Gillman, 2003). Obesity has reached epidemic proportions in the United States with more than 20% of adults defined as clinically obese and an additional 30% defined as overweight. In 1999, 13% of children aged 6–11 years and 14% of adolescents aged 12–19 years in the United . . . [Full Text of this Article]


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