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ToxSci Advance Access originally published online on December 27, 2007
Toxicological Sciences 2008 103(1):215-216; doi:10.1093/toxsci/kfm309
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© The Author 2007. Published by Oxford University Press on behalf of the Society of Toxicology. All rights reserved. For Permissions, please email: journals.permissions@oxfordjournals.org

Letter regarding: "Paraquat: The Red Herring of Parkinson's Disease Research"

Deborah A. Cory-Slechta*, Mona Thiruchelvam{dagger} and Donato A. Di Monte{ddagger}

* Department of Environmental Medicine, University of Rochester School of Medicine and Dentistry, Rochester, New York 14642 {dagger} Environmental and Occupational Health Sciences Institute, Robert Wood Johnson Medical School, Piscataway, New Jersey 08854 {ddagger} The Parkinson's Institute, Sunnyvale, California 94085

Received November 30, 2007; accepted December 1, 2007

The first 10% of the full text of this article appears below.

We write this letter in response to the recent editorial entitled "Paraquat: the Red Herring of Parkinson's Disease Research" by G. W. Miller. In our opinion, this editorial fails to appreciate that Parkinson's disease (PD) is a complex disease with multiple interactive etiologic risk factors and that our current animals models, as imperfect as they may be (is there such thing as a "perfect" model?), are critical tools for elucidating the nature and interplay of these factors. The article attempts to support a point of view based on . . . [Full Text of this Article]


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