ToxSci Advance Access originally published online on February 23, 2009
Toxicological Sciences 2009 108(2):223-224; doi:10.1093/toxsci/kfp032
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© The Author 2009. Published by Oxford University Press on behalf of the Society of Toxicology. All rights reserved. For permissions, please email: journals.permissions@oxfordjournals.org
Safety Evaluation of Silver Nanoparticles: Inhalation Model for Chronic Exposure
Applied Biotechnology Branch, Human Effectiveness Directorate, 711th Human Performance Wing, Air Force Research Laboratory, Wright-Patterson AFB, OH
1 To whom correspondence should be addressed at Applied Biotechnology Branch, Human Effectiveness Directorate, 711th Human Performance Wing, Air Force Research Laboratory, Wright-Patterson AFB, OH. E-mail: saber.hussain@wpafb.af.mil.
Received February 9, 2009; accepted February 10, 2009
| The first 10% of the full text of this article appears below. |
The rapid emergence of nanotechnology including production of engineered nanoparticles has provided many exciting advancements in science and is likely to provide our society with a continuous range of consumer products with advanced technology applications. For example, use of the inexhaustible propensity of inherent antimicrobial activity for silver nanoparticles has resulted in their widespread application and use in consumer products such as disinfectants, deodorants, antimicrobial sprays and powders, bedding, machine washers, humidifiers, water purification and air filters, toothpaste, shampoo and rinse, reusable bottle nursing nipples, in multiple fabrics, kitchen utensils, and toys. Among the 580 consumer products containing known nanomaterials, the most common material mentioned in product descriptions is silver-based nanoparticles (Woodrow Wilson International Center for Scholars, 2007
). Human exposure likelihood and needed risk exposure analysis to