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Toxicological Sciences 64, 282-283 (2001)
Copyright © 2001 by the Society of Toxicology

Carcinogencity Bioassays of Bisphenol A, 4-Vinylcyclohexene Diepoxide, and 4-Vinycyclohexene

James Huff

National Institute of Environmental Health Sciences P. O. Box 12233 Research Triangle Park, NC 27709 E-mail: huff1@niehs.nih.gov.

To the Editor:

Two papers (Yoshihara et al., 2001Go; Devine et al., 2001Go) in the August issue of Toxicological Sciences dealt with chemicals that have been tested for carcinogenicity by the National Toxicology Program (NTP). Both papers explored mechanisms of toxicity of these chemicals; the former dealt with metabolic activation of bisphenol A, and the latter explored mechanisms of ovarian toxicity (Hoyer et al., 2001Go), both perhaps relevant to the carcinogenicity of these chemicals. Because neither of the articles mentioned these NTP bioassays, I wish to bring this additional and relevant information to the attention of your readers, especially with the renewed interest in bisphenol A, a well-known environmental endocrine disruptor chemical. . . . [Full Text of this Article]

Bisphenol A
4-Vinylcyclohexene Diepoxide
4-Vinylcyclohexene
REFERENCES


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J. Huff
Carcinogenicity of Bisphenol A Revisited
Toxicol. Sci., December 1, 2002; 70(2): 281 - 283.
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I. C. Munro, L. A. Haighton, J. J. Hlywka, B. S. Lynch, J. Doull, and R. Kroes
Reply
Toxicol. Sci., December 1, 2002; 70(2): 283 - 284.
[Full Text] [PDF]

Home page
 Toxicol SciHome page
I. C. Munro, L. A. Haighton, J. J. Hlywka, B. S. Lynch, J. Doull, and R. Kroes
Carcinogenicity Bioassay of Bisphenol A
Toxicol. Sci., April 1, 2002; 66(2): 356 - 356.
[Full Text] [PDF]