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ToxSci Advance Access originally published online on December 9, 2005
Toxicological Sciences 2006 90(2):304-308; doi:10.1093/toxsci/kfj071
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© The Author 2005. Published by Oxford University Press on behalf of the Society of Toxicology. All rights reserved. For Permissions, please email: journals.permissions@oxfordjournals.org

FORUM

Priority Setting in the REACH System

Sven Ove Hansson and Christina Rudén1

Royal Institute of Technology, Department of Philosophy, Stockholm, Sweden

Received July 28, 2005; accepted December 5, 2005

Due to the large number of chemicals for which toxicological and ecotoxicological information is lacking, priority setting for data acquisition is a major concern in chemicals regulation. In the current European system, two administrative priority-setting criteria are used, namely novelty (i.e., time of market introduction) and production volume. In the proposed Registration, Evaluation, Authorisation and Restriction of Chemicals (REACH) system, the novelty criterion is no longer used, and production volume will be the main priority-setting criterion for testing requirements, supplemented in some cases with hazard indications obtained from QSAR modelling. This system for priority setting has severe weaknesses. In this paper we propose that a multicriteria system should be developed that includes at least three additional criteria: chemical properties, results from initial testing in a tiered system, and voluntary testing for which efficient incentives can be created. Toxicological and decision-theoretical research is needed to design testing systems with validated priority-setting mechanisms.

Key Words: chemicals control; risk assessment; risk management; REACH; tiered testing.


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