ToxSci Advance Access originally published online on September 4, 2006
Toxicological Sciences 2006 94(2):439; doi:10.1093/toxsci/kfl099
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© The Author 2006. Published by Oxford University Press on behalf of the Society of Toxicology. All rights reserved. For Permissions, please email: journals.permissions@oxfordjournals.org
TO THE EDITOR
Department of Environmental Medicine and Department of Pediatrics/Neonatology, University of Rochester, 575 Elmwood Avenue, Medical Center Box 850, Rochester, New York 14642
E-mail: gunter_oberdorster@urmc.rochester.edu
Received July 31, 2006; accepted August 2, 2006
| The first 10% of the full text of this article appears below. |
Phalen et al. (2006)
have opened an important discussion on a key question of in vitro dosing of cells with poorly soluble particles, focusing on tracheobronchial epithelial cells. Indeed, this paper is very timely, given the increasing number of publications using exorbitantly high in vitro doses of particles and extrapolating from those results potential adverse