Volume 152, Issue 2, August 2016

Look Inside ToxSci

From the Editor’s Desk, Editor’s Highlights, Letters to the Editor

Toxicological Sciences, Volume 152, Issue 2, August 2016, Pages 257–261, https://doi.org/10.1093/toxsci/kfw113

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Editorial

Three Years After

Gary W. Miller

Toxicological Sciences, Volume 152, Issue 2, August 2016, Pages 262–263, https://doi.org/10.1093/toxsci/kfw107

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Contemporary Review: Review of MicroRNA Biomarkers

MicroRNA Biomarkers of Toxicity in Biological Matrices

Alison H. Harrill and others

Toxicological Sciences, Volume 152, Issue 2, August 2016, Pages 264–272, https://doi.org/10.1093/toxsci/kfw090

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MicroRNA Biomarkers for Retinal Toxicity

Editor's Highlight: Plasma miR-183/96/182 Cluster and miR-124 are Promising Biomarkers of Rat Retinal Toxicity

Qinghai Peng and others

Toxicological Sciences, Volume 152, Issue 2, August 2016, Pages 273–283, https://doi.org/10.1093/toxsci/kfw085

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Modeling of Nanoparticles in Nasal Cavities

From the Cover: Comparative Numerical Modeling of Inhaled Nanoparticle Deposition in Human and Rat Nasal Cavities

Jingliang Dong and others

Toxicological Sciences, Volume 152, Issue 2, August 2016, Pages 284–296, https://doi.org/10.1093/toxsci/kfw087

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P53 Signaling and Organogenesis

Editor's Highlight: Hydroxyurea Exposure Activates the P53 Signaling Pathway in Murine Organogenesis-Stage Embryos

Nazem El Husseini and others

Toxicological Sciences, Volume 152, Issue 2, August 2016, Pages 297–308, https://doi.org/10.1093/toxsci/kfw089

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PCB 126 Alters Unsaturated Fatty Acid Homeostasis

3,3′,4,4′,5-Pentachlorobiphenyl (PCB 126) Decreases Hepatic and Systemic Ratios of Epoxide to Diol Metabolites of Unsaturated Fatty Acids in Male Rats

Xianai Wu and others

Toxicological Sciences, Volume 152, Issue 2, August 2016, Pages 309–322, https://doi.org/10.1093/toxsci/kfw084

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Computational Analysis of In Vitro Toxicology for Cell Stress and Cytotoxicity

Editor's Highlight: Analysis of the Effects of Cell Stress and Cytotoxicity on In Vitro Assay Activity Across a Diverse Chemical and Assay Space

Richard Judson and others

Toxicological Sciences, Volume 152, Issue 2, August 2016, Pages 323–339, https://doi.org/10.1093/toxsci/kfw092

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Structural Modeling of Pentachlorobiphenyl 118 Hydroxylation

From the Cover: Structural Determinants of the Position of 2,3′,4,4′,5-Pentachlorobiphenyl (CB118) Hydroxylation by Mammalian Cytochrome P450 Monooxygenases

Shintaro Mise and others

Toxicological Sciences, Volume 152, Issue 2, August 2016, Pages 340–348, https://doi.org/10.1093/toxsci/kfw086

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Arsenite and Mitochondrial Function in C. Elegans

From the Cover: Arsenite Uncouples Mitochondrial Respiration and Induces a Warburg-like Effect in Caenorhabditis elegans

Anthony L. Luz and others

Toxicological Sciences, Volume 152, Issue 2, August 2016, Pages 349–362, https://doi.org/10.1093/toxsci/kfw093

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Mutagenic Effects of Benzo(a)pyrene in Mouse Sperm Stem Cells

Benzo(a)pyrene Is Mutagenic in Mouse Spermatogonial Stem Cells and Dividing Spermatogonia

Jason M. O’Brien and others

Toxicological Sciences, Volume 152, Issue 2, August 2016, Pages 363–371, https://doi.org/10.1093/toxsci/kfw088

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Increased Vulnerability of Mouse Fetal Ovary to Benzo(a)pyrene

The Mouse Fetal Ovary Has Greater Sensitivity Than the Fetal Testis to Benzo[a]pyrene-Induced Germ Cell Death

Jinhwan Lim and others

Toxicological Sciences, Volume 152, Issue 2, August 2016, Pages 372–381, https://doi.org/10.1093/toxsci/kfw083

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WNT/β-Catenin Signaling in ES Cells to Identify Teratogens

Editor's Highlight: Identification and Characterization of Teratogenic Chemicals Using Embryonic Stem Cells Isolated From a Wnt/β-Catenin-Reporter Transgenic Mouse Line

Josephine Kugler and others

Toxicological Sciences, Volume 152, Issue 2, August 2016, Pages 382–394, https://doi.org/10.1093/toxsci/kfw094

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Doxorubicin and Adverse Effects in Pancreatic β-Cells

Mechanisms of Doxorubicin Toxicity in Pancreatic β-Cells

Emma A. Heart and others

Toxicological Sciences, Volume 152, Issue 2, August 2016, Pages 395–405, https://doi.org/10.1093/toxsci/kfw096

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Evaluation of the Nanoparticle Biocorona

From the Cover: Disease-Induced Disparities in Formation of the Nanoparticle-Biocorona and the Toxicological Consequences

Jonathan H. Shannahan and others

Toxicological Sciences, Volume 152, Issue 2, August 2016, Pages 406–416, https://doi.org/10.1093/toxsci/kfw097

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FXR Regulation and Pyrazinamide

Pyrazinamide Induced Rat Cholestatic Liver Injury through Inhibition of FXR Regulatory Effect on Bile Acid Synthesis and Transport

Hong-Li Guo and others

Toxicological Sciences, Volume 152, Issue 2, August 2016, Pages 417–428, https://doi.org/10.1093/toxsci/kfw098

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COVER

Cover

Toxicological Sciences, Volume 152, Issue 2, August 2016, Page i1, https://doi.org/10.1093/toxsci/kfv290

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STANDING MATERIAL

Editorial Board

Toxicological Sciences, Volume 152, Issue 2, August 2016, Page i2, https://doi.org/10.1093/toxsci/kfv291

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Subscriptions

Toxicological Sciences, Volume 152, Issue 2, August 2016, Page i3, https://doi.org/10.1093/toxsci/kfv292

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Table of Contents

Toxicological Sciences, Volume 152, Issue 2, August 2016, Page i4, https://doi.org/10.1093/toxsci/kfv293

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