Toxicological Sciences

TOXICOLOGICAL HIGHLIGHT

David B. Warheit

How Meaningful are the Results of Nanotoxicity Studies in the Absence of Adequate Material Characterization?
Toxicol. Sci. 2008 101: 183-185; doi:10.1093/toxsci/kfm279 [Extract] [FREE Full Text] [PDF] [Request Permissions]  

REVIEW

Get checked abstract Curtis D. Klaassen and Hong Lu

Xenobiotic Transporters: Ascribing Function from Gene Knockout and Mutation Studies
ToxSci Advance Access published on August 13, 2007
Toxicol. Sci. 2008 101: 186-196; doi:10.1093/toxsci/kfm214 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

BIOTRANSFORMATION AND TOXICOKINETICS

Get checked abstract Kyu-Bong Kim, Sathanandam S. Anand, Hyo Jung Kim, Catherine A. White, and James V. Bruckner

Toxicokinetics and Tissue Distribution of Deltamethrin in Adult Sprague–Dawley Rats
ToxSci Advance Access published on December 3, 2007
Toxicol. Sci. 2008 101: 197-205; doi:10.1093/toxsci/kfm277 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

ENVIRONMENTAL TOXICOLOGY

Get checked abstract Freddy Dardenne, Stefan Van Dongen, Ingrid Nobels, Roel Smolders, Wim De Coen, and Ronny Blust

Mode of Action Clustering of Chemicals and Environmental Samples on the Bases of Bacterial Stress Gene Inductions
ToxSci Advance Access published on October 20, 2007
Toxicol. Sci. 2008 101: 206-214; doi:10.1093/toxsci/kfm262 [Abstract] [FREE Full Text] [PDF] [Supplementary Data] [Request Permissions]  

GENETIC TOXICOLOGY

Get checked abstract Koichi Hasegawa, Satsuki Miwa, Kazunori Isomura, Kaname Tsutsumiuchi, Hajime Taniguchi, and Johji Miwa

Acrylamide-Responsive Genes in the Nematode Caenorhabditis elegans
ToxSci Advance Access published on November 7, 2007
Toxicol. Sci. 2008 101: 215-225; doi:10.1093/toxsci/kfm276 [Abstract] [FREE Full Text] [PDF] [Supplementary Data] [Request Permissions]  

IMMUNOTOXICOLOGY

Get checked abstract Keiko Nohara, Kana Ao, Yoshimi Miyamoto, Takehiro Suzuki, Satoru Imaizumi, Yukiyo Tateishi, Seiichi Omura, Chiharu Tohyama, and Takahiro Kobayashi

Arsenite-Induced Thymus Atrophy is Mediated by Cell Cycle Arrest: A Characteristic Downregulation of E2F-Related Genes Revealed by a Microarray Approach
ToxSci Advance Access published on November 12, 2007
Toxicol. Sci. 2008 101: 226-238; doi:10.1093/toxsci/kfm268 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

IN VITRO TOXICOLOGY AND ALTERNATIVE TESTING

HIGHLIGHTED ARTICLE:

Get checked abstract Richard C. Murdock, Laura Braydich-Stolle, Amanda M. Schrand, John J. Schlager, and Saber M. Hussain

Characterization of Nanomaterial Dispersion in Solution Prior to In Vitro Exposure Using Dynamic Light Scattering Technique
ToxSci Advance Access published on September 13, 2007
Toxicol. Sci. 2008 101: 239-253; doi:10.1093/toxsci/kfm240 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Get checked abstract Dany S. Muller, Pascale Houpert, Jean Cambar, and Marie-Hélène Hengé-Napoli

Role of the Sodium-Dependent Phosphate Cotransporters and Absorptive Endocytosis in the Uptake of Low Concentrations of Uranium and Its Toxicity at Higher Concentrations in LLC-PK₁ Cells
ToxSci Advance Access published on November 12, 2007
Toxicol. Sci. 2008 101: 254-262; doi:10.1093/toxsci/kfm266 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Get checked abstract Catherine McDermott, Ashley Allshire, Frank van Pelt, and James J. A. Heffron

In Vitro Exposure of Jurkat T-Cells to Industrially Important Organic Solvents in Binary Combination: Interaction Analysis
ToxSci Advance Access published on November 2, 2007
Toxicol. Sci. 2008 101: 263-274; doi:10.1093/toxsci/kfm274 [Abstract] [FREE Full Text] [PDF] [Supplementary Data] [Request Permissions]  

NEUROTOXICOLOGY

Get checked abstract Celia Fischer, Anders Fredriksson, and Per Eriksson

Coexposure of Neonatal Mice to a Flame Retardant PBDE 99 (2,2',4,4',5-Pentabromodiphenyl Ether) and Methyl Mercury Enhances Developmental Neurotoxic Defects
ToxSci Advance Access published on November 2, 2007
Toxicol. Sci. 2008 101: 275-285; doi:10.1093/toxsci/kfm271 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Get checked abstract Ming-Huan Chan, Yu-Chi Tang, Te-Hsiung Chien, and Hwei-Hsien Chen

Toluene Exposure during the Brain Growth Spurt Reduced Behavioral Responses to Nicotine in Young Adult Rats: A Potential Role for Nicotinic Acetylcholine Receptors in Fetal Solvent Syndrome
ToxSci Advance Access published on October 20, 2007
Toxicol. Sci. 2008 101: 286-293; doi:10.1093/toxsci/kfm264 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Get checked abstract Robert F. Berman, Isaac N. Pessah, Peter R. Mouton, Deepak Mav, and Jean Harry

Low-Level Neonatal Thimerosal Exposure: Further Evaluation of Altered Neurotoxic Potential in SJL Mice
ToxSci Advance Access published on October 31, 2007
Toxicol. Sci. 2008 101: 294-309; doi:10.1093/toxsci/kfm265 [Abstract] [FREE Full Text] [PDF] [Supplementary Data] [Request Permissions]  

Get checked abstract Christoffer Tamm, Farideh Sabri, and Sandra Ceccatelli

Mitochondrial-Mediated Apoptosis in Neural Stem Cells Exposed to Manganese
ToxSci Advance Access published on October 31, 2007
Toxicol. Sci. 2008 101: 310-320; doi:10.1093/toxsci/kfm267 [Abstract] [FREE Full Text] [PDF] [Supplementary Data] [Request Permissions]  

REPRODUCTIVE AND DEVELOPMENTAL TOXICOLOGY

Get checked abstract Andrea C. Aragon, Phillip G. Kopf, Matthew J. Campen, Janice K. Huwe, and Mary K. Walker

In Utero and Lactational 2,3,7,8-Tetrachlorodibenzo-p-dioxin Exposure: Effects on Fetal and Adult Cardiac Gene Expression and Adult Cardiac and Renal Morphology
ToxSci Advance Access published on November 1, 2007
Toxicol. Sci. 2008 101: 321-330; doi:10.1093/toxsci/kfm272 [Abstract] [FREE Full Text] [PDF] [Supplementary Data] [Request Permissions]  

SYSTEMS TOXICOLOGY

Get checked abstract Ashu Johri, Alok Dhawan, Ram Lakhan Singh, and Devendra Parmar

Persistence in Alterations in the Ontogeny of Cerebral and Hepatic Cytochrome P450s following Prenatal Exposure to Low Doses of Lindane
ToxSci Advance Access published on November 5, 2007
Toxicol. Sci. 2008 101: 331-340; doi:10.1093/toxsci/kfm269 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Get checked abstract Priscilla L. K. Lim, Jianchao Liu, Mei L. Go, and Urs A. Boelsterli

The Mitochondrial Superoxide/Thioredoxin-2/Ask1 Signaling Pathway is Critically Involved in Troglitazone-Induced Cell Injury to Human Hepatocytes
ToxSci Advance Access published on November 1, 2007
Toxicol. Sci. 2008 101: 341-349; doi:10.1093/toxsci/kfm273 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Get checked abstract Naoki Kiyosawa, Joshua C. Kwekel, Lyle D. Burgoon, Kurt J. Williams, Colleen Tashiro, Brock Chittim, and Timothy R. Zacharewski

o,p'-DDT Elicits PXR/CAR-, Not ER-, Mediated Responses in the Immature Ovariectomized Rat Liver
ToxSci Advance Access published on November 5, 2007
Toxicol. Sci. 2008 101: 350-363; doi:10.1093/toxsci/kfm275 [Abstract] [FREE Full Text] [PDF] [Supplementary Data] [Request Permissions]  

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