Toxicological Sciences

ISSUES:

S. STANLEY YOUNG

Are There Location/Cage/Systematic Nontreatment Effects in Long-Term Rodent Studies? A Question Revisited
Toxicol. Sci. 1989 13: 183-188; doi:10.1093/toxsci/13.2.183 [Abstract] [PDF] [Request Permissions]  

J. K. HASEMAN

Commentary on "Are There Location/Cage/Systematic Nontreatment Effects in Long-Term Rodent Studies? A Question Revisited"
Toxicol. Sci. 1989 13: 189-192; doi:10.1093/toxsci/13.2.189 [PDF] [Request Permissions]  

SYMPOSIUM: Toxicology of Medical Device Materials:

PETER L. GOERING and W. DON GALLOWAY

Introduction to the Symposium Presented at the 1988 Annual Meeting of The society of Toxicology
Toxicol. Sci. 1989 13: 193-195; doi:10.1093/toxsci/13.2.193 [Abstract] [PDF] [Request Permissions]  

SHARON J. NORTHUP

Current Problems Associated with Toxicity Evaluation of Medical Device Materials and Future Research Needs
Toxicol. Sci. 1989 13: 196-204; doi:10.1093/toxsci/13.2.196 [Abstract] [PDF] [Request Permissions]  

F. WILLIAM SUNDERMAN, Jr.

Carcinogenicity of Metal Alloys in Orthopedic Prostheses: Clinical and Experimental Studies
Toxicol. Sci. 1989 13: 205-216; doi:10.1093/toxsci/13.2.205 [Abstract] [PDF] [Request Permissions]  

ROGER E. MARCHANT

The Cage Implant System for Determining in Vivo Bicmmpatibility of Medical Device Material
Toxicol. Sci. 1989 13: 217-227; doi:10.1093/toxsci/13.2.217 [Abstract] [PDF] [Request Permissions]  

LEE W. HENDERSON

Immunotoxicity of Blood-Synthetic Membrane interactions
Toxicol. Sci. 1989 13: 228-234; doi:10.1093/toxsci/13.2.228 [PDF] [Request Permissions]  

REGULAR ARTICLE:

KENNETH G. BROWN and LINDA S. ERDREICH

Statistical Uncertainty in the No-Observed-Adverse-Effect Level
Toxicol. Sci. 1989 13: 235-244; doi:10.1093/toxsci/13.2.235 [Abstract] [PDF] [Request Permissions]  

KIMBERLEY A. TREINEN, ROBERT E. CHAPIN, DUSHYANT K. GULATI, ROBIN MOUNCE, LISA Z. MORRIS, and JAMES C. LAMB, IV

Reproductive Toxicity of 2,2-Bis(bromomethyl)-1,3-propanediol in a Continuous Breeding Protocol in Swiss (CD-1) Mice
Toxicol. Sci. 1989 13: 245-255; doi:10.1093/toxsci/13.2.245 [Abstract] [PDF] [Request Permissions]  

JOHN H. MCDONOUGH, JR., NANCY K. JAAX, RENEE A. CROWLEY, MARY Z. MAYS, and HAROLD E. MODROW

Atropine and/or Diazepam Therapy Protects against Soman-Induced Neural and Cardiac Pathology
Toxicol. Sci. 1989 13: 256-276; doi:10.1093/toxsci/13.2.256 [Abstract] [PDF] [Request Permissions]  

URSZULA ORLINSKA, JACK W. OLSON, SARAH ALLEN GEBB, and MARK N. GILLESPIE

Acetylated Polyamines in Lungs from Rats with Monocrotaline-Induced Pneumotoxicity
Toxicol. Sci. 1989 13: 277-284; doi:10.1093/toxsci/13.2.277 [Abstract] [PDF] [Request Permissions]  

GARY B. KOLESAR, WAHEED H. SIDDIQUI, ROBERT G. GEIL, REGINA M. MALCZEWSKI, and EDWARD J. HOBBS

Subchronic Inhalation Toxicity of Tetramethoxysilane in Rats
Toxicol. Sci. 1989 13: 285-295; doi:10.1093/toxsci/13.2.285 [Abstract] [PDF] [Request Permissions]  

P. A. MCANULTY, M. J. COLLIER, J. ENTICOTT, J. M. TESH, D. A. MAYHEW, C. PHIL COMER, JERRY J. HJELLE, and FRANK N. KOTSONIS

Absence of Developmental Effects in CF-1 Mice Exposed to Aspartame in Utero
Toxicol. Sci. 1989 13: 296-302; doi:10.1093/toxsci/13.2.296 [Abstract] [PDF] [Request Permissions]  

W. C. DAUGHTREY, P. J. WIER, K. A. TRAUL, R. W. BILES, and G. F. EGAN

Evaluation of the Teratogenic Potential of Octyl Acetate in Rats
Toxicol. Sci. 1989 13: 303-309; doi:10.1093/toxsci/13.2.303 [Abstract] [PDF] [Request Permissions]  

M. E. MAYES, G. A. HELD, C. LAU, J. C. SEELY, R. M. ROE, W. C. DAUTERMAN, and C. Y. KAWANISHI

Characterization of the Mammalian Toxicity of the Crystal Polypeptides of Bacillus thuringiensis subsp. israelensis
Toxicol. Sci. 1989 13: 310-322; doi:10.1093/toxsci/13.2.310 [Abstract] [PDF] [Request Permissions]  

S. B. HARRIS, J. L. SCHARDEIN, C. E. ULRICH, and S. A. RIDLON

Inhalation Developmental Toxicity Study of Propylene Oxide in Fischer 344 Rats
Toxicol. Sci. 1989 13: 323-331; doi:10.1093/toxsci/13.2.323 [Abstract] [PDF] [Request Permissions]  

AKIHIRO HAGIWARA, BHALCHANDRA A. DIWAN, and JERROLD M. WARD

Barbital Sodium, a Tumor Promoter for Kidney Tubules, Urinary Bladder, and Liver of the F344 Rat, Induces Persistent Increases in Levels of DNA Synthesis in Renal Tubules but Not in Urinary Bladder Epithelium or Hepatocytes
Toxicol. Sci. 1989 13: 332-340; doi:10.1093/toxsci/13.2.332 [Abstract] [PDF] [Request Permissions]  

RENUKA DAYAL, ANDREAS GESCHER, ERNEST S. HARPUR, IONA PRATT, and J. KEVIN CHIPMAN

Comparison of the Hepatotoxicity in Mice and the Mutagenicity of Three Nitroalkanes
Toxicol. Sci. 1989 13: 341-348; doi:10.1093/toxsci/13.2.341 [Abstract] [PDF] [Request Permissions]  

Announcements:

Announcements
Toxicol. Sci. 1989 13: 349-350; doi:10.1093/toxsci/13.2.349 [PDF] [Request Permissions]  

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