Toxicological Sciences

SOT POSITION PAPER:

Comments on the LD50 and Acute Eye and Skin Irritation Tests: Prepared by the Animals in Research Committee of The Society of Toxicology and Approved by the SOT Council
Toxicol. Sci. 1989 13: 621-623; doi:10.1093/toxsci/13.4.621 [Abstract] [PDF] [Request Permissions]  

SYMPOSIUM OVERVIEW:

ROGENE F. HENDERSON

Symposium on Lung Cancer Risk of Exposure to Radon
Toxicol. Sci. 1989 13: 624-634; doi:10.1093/toxsci/13.4.624 [PDF] [Request Permissions]  

REGULAR ARTICLES:

D. E. RODWELL, R. D. WILSON, M. D. NEMEC, and M. D. MERCIECA

Teratogenic Assessment of 2,4-Dichlorophenol in Fischer 344 Rats
Toxicol. Sci. 1989 13: 635-640; doi:10.1093/toxsci/13.4.635 [Abstract] [PDF] [Request Permissions]  

JULIA D. GEORGE, CATHERINE J. PRICE, MELISSA C. MARR, BRIAN M. SADLER, BERNARD A. SCHWETZ, LINDA S. BIRNBAUM, and RICHARD E. MORRISSEY

Developmental Toxicity of 1,1,1-Trichloroethane in CD Rats
Toxicol. Sci. 1989 13: 641-651; doi:10.1093/toxsci/13.4.641 [Abstract] [PDF] [Request Permissions]  

P. SULLIVAN-JONES, C. A. KIMMEL, and G. L. KIMMEL

Prenatal Reserpine Exposure Alters Cardiovascular Parameters in Rat Offspring
Toxicol. Sci. 1989 13: 652-661; doi:10.1093/toxsci/13.4.652 [Abstract] [PDF] [Request Permissions]  

RICHARD C. ZANGAR, DAVID L. SPRINGER, RAY L. BUSCHBOM, and DENNIS D. MAHLUM

Comparison of Fetotoxic Effects of a Dermally Applied Complex Organic Mixture in Rats and Mice
Toxicol. Sci. 1989 13: 662-669; doi:10.1093/toxsci/13.4.662 [Abstract] [PDF] [Request Permissions]  

SUSAN E. GEORGE, DEBRA B. WALSH, ANDREW G. STEAD, and LARRY D. CLAXTON

Effect of Ampicillin-lnduced Alterations in Murine Intestinal Microbiota on the Survival and Competition of Environmentally Released Pseudomonads
Toxicol. Sci. 1989 13: 670-680; doi:10.1093/toxsci/13.4.670 [Abstract] [PDF] [Request Permissions]  

THOMAS A. MARKS, GARY L. KIMMEL, and ROBERT E. STAPLES

Influence of Symmetrical Polychlorinated Biphenyl Isomers on Embryo and Fetal Development in Mice: II. Comparison of 4,4'-Dichlorobiphenyl, 3,3'4,4'-Tetrachlorobiphenyl, 3,3'5,5'-Tetrachlorobiphenyl, and 3,3'4,4'-Tetramethylbiphenyl
Toxicol. Sci. 1989 13: 681-693; doi:10.1093/toxsci/13.4.681 [Abstract] [PDF] [Request Permissions]  

ROBERT E. DUDLEY, SEAN E. PATTERSON, SAMUEL V. MACHOTKA, and JAMES W. KESTERSON

One-Month Inhalation Toxicity Study of Tulobuterol Hydrochloride in Rats and Dogs
Toxicol. Sci. 1989 13: 694-701; doi:10.1093/toxsci/13.4.694 [Abstract] [PDF] [Request Permissions]  

DAVID B. WARHEIT, LAURA A. KINNEY, MICHAEL C. CARAKOSTAS, and PAUL E. ROSS

Inhalation Toxicity Study of Formamide in Rats
Toxicol. Sci. 1989 13: 702-713; doi:10.1093/toxsci/13.4.702 [Abstract] [PDF] [Request Permissions]  

MICHAEL P. CARVER and J. EDMOND RIVIERE

Percutaneous Absorption and Excretion of Xenobiotics after Topical and Intravenous Administration to Pigs
Toxicol. Sci. 1989 13: 714-722; doi:10.1093/toxsci/13.4.714 [Abstract] [PDF] [Request Permissions]  

MARTHA W. HARRIS, LINDA C. URAIH, and LINDA S. BIRNBAUM

Acute Toxicity of Perfluorodecanoic Acid in C57BL/6 Mice Differs from 2,3,7,8-Tetrachlorodibenzo-p-dioxin
Toxicol. Sci. 1989 13: 723-736; doi:10.1093/toxsci/13.4.723 [Abstract] [PDF] [Request Permissions]  

D. M. HOOVER, M. K. BUENING, R. N. TAMURA, and E. STEINBERGER

Effects of Cefamandole on Spermatogenic Development of Young CD Rats
Toxicol. Sci. 1989 13: 737-746; doi:10.1093/toxsci/13.4.737 [Abstract] [PDF] [Request Permissions]  

RICHARD E. MORRISSEY, JAMES C. LAMB, IV, RICHARD W. MORRIS, ROBERT E. CHAPIN, DUSHYANT K. GULATI, and JERROLD J. HEINDEL

Results and Evaluations of 48 Continuous Breeding Reproduction Studies Conducted in Mice
Toxicol. Sci. 1989 13: 747-777; doi:10.1093/toxsci/13.4.747 [Abstract] [PDF] [Request Permissions]  

KAREN S. PROBST, GARY L. HIGDON, LAWRENCE F. FISHER, JOHN P. MCGRATH, ELIZABETH R. ADAMS, and JOHN L. EMMERSON

Preclinical Toxicology Studies with Nizatidine, A New H₂-Receptor Antagonist: Acute, Subchronic, and Chronic Toxicity Evaluations
Toxicol. Sci. 1989 13: 778-792; doi:10.1093/toxsci/13.4.778 [Abstract] [PDF] [Request Permissions]  

R. KANNAN, J. S. M. SARMA, M. GUHA, and K. VENKATARAMAN

Tissue Drug Accumulation and Ultrastructural Changes during Amiodarone Administration in Rats
Toxicol. Sci. 1989 13: 793-803; doi:10.1093/toxsci/13.4.793 [Abstract] [PDF] [Request Permissions]  

J. J. HEINDEL, A. S. BERKOWITZ, G. KYLE, G. KYLE LUTHRA, and J. V. BRUCKNER

Assessment in Rats of the Gonadotoxic and Hepatorenal Toxic Potential of Dibromochloropropane (DBCP) in Drinking Water
Toxicol. Sci. 1989 13: 804-815; doi:10.1093/toxsci/13.4.804 [Abstract] [PDF] [Request Permissions]  

NENAD RAOS and KAZIMIERZ S. KASPRZAK

Allosteric Binding of Nickel(II) to Calmodulin
Toxicol. Sci. 1989 13: 816-822; doi:10.1093/toxsci/13.4.816 [Abstract] [PDF] [Request Permissions]  

WERNER STÖBER, PAUL E. MORROW, and MARK D. HOOVER

Compartmental Modeling of the Long-Term Retention of Insoluble Particles Deposited in the Alveolar Region of the Lung
Toxicol. Sci. 1989 13: 823-842; doi:10.1093/toxsci/13.4.823 [Abstract] [PDF] [Request Permissions]  

E. E. SIKORSKI, J. A. MCCAY, K. L. WHITE, JR., S. G. BRADLEY, and A. E. MUNSON

Immunotoxicity of the Semiconductor Gallium Arsenide in Female B6C3F1 Mice
Toxicol. Sci. 1989 13: 843-858; doi:10.1093/toxsci/13.4.843 [Abstract] [PDF] [Request Permissions]  

SHORT COMMUNICATION:

JOHN B. BARTOLONE, STEVEN D. COHEN, and EDWARD A. KHAIRALLAH

Immunohistochemical Localization of Acetaminophen-Bound Liver Proteins
Toxicol. Sci. 1989 13: 859-862; doi:10.1093/toxsci/13.4.859 [Abstract] [PDF] [Request Permissions]  

LETTERS TO THE EDITOR:

MARCELA JENSEN, LOIS M. NEWMAN, and E. MARSHALL JOHNSON

LETTERS TO THE EDITOR: Re: Problems in validation of in vitro developmental toxicity assays
Toxicol. Sci. 1989 13: 863-865; doi:10.1093/toxsci/13.4.863 [PDF] [Request Permissions]  

VERNON E. STEELE and RICHARD E. MORRISSEY

Reply
Toxicol. Sci. 1989 13: 865; doi:10.1093/toxsci/13.4.865 [PDF] [Request Permissions]  

JAY I. GOODMAN

To the Editor
Toxicol. Sci. 1989 13: 865-866; doi:10.1093/toxsci/13.4.865-a [PDF] [Request Permissions]  

S. STANLEY YOUNG

Reply
Toxicol. Sci. 1989 13: 866-867; doi:10.1093/toxsci/13.4.866 [PDF] [Request Permissions]  

ANNOUNCEMENTS:

International Conference on Biological Effects of Dietary Restriction
Toxicol. Sci. 1989 13: 868-869; doi:10.1093/toxsci/13.4.868 [PDF] [Request Permissions]  

AUTHOR INDEX FOR VOLUME 13:

Author Index for Volume 13
Toxicol. Sci. 1989 13: 870-872; doi:10.1093/toxsci/13.4.870 [PDF] [Request Permissions]  

SUBJECT INDEX FOR VOLUMES 1213:

Subject Index for Volumes 12–13
Toxicol. Sci. 1989 13: 873-890; doi:10.1093/toxsci/13.4.873 [PDF] [Request Permissions]  

CHEMICAL INDEX FOR VOLUMES 1213:

Chemical Index for Volumes 12–13
Toxicol. Sci. 1989 13: 891-893; doi:10.1093/toxsci/13.4.891 [PDF] [Request Permissions]  

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