Toxicological Sciences

SYMPOSIUM OVERVIEW:

ROBERT J. KAVLOCK

Symposium on Application of Pharmacokinetics in Developmental Toxicity Risk Assessments
Toxicol. Sci. 1991 16: 213-232; doi:10.1093/toxsci/16.2.213 [PDF] [Request Permissions]  

DONALD R. MATTISON, ERNICE BLANN, and ANTOINE MALEK

Physiological Alterations during Pregnancy: Impact on Toxicokinetics
Toxicol. Sci. 1991 16: 215-218; doi:10.1093/toxsci/16.2.215 [PDF] [Request Permissions]  

HEINZ NAU

Pharmacokinetic Considerations in the Design and Interpretation of Developmental Toxicity Studies
Toxicol. Sci. 1991 16: 219-221; doi:10.1093/toxsci/16.2.219 [PDF] [Request Permissions]  

JOHN F. YOUNG

Correlation of Pharmacokinetic Data with Endpoints of Developmental Toxicity
Toxicol. Sci. 1991 16: 222-224; doi:10.1093/toxsci/16.2.222 [PDF] [Request Permissions]  

R. J. KAVLOCK, L. A. OGLESBY, L. L. HALL, H. L. FISHER, F. COPELAND, T. LOGSDON, and M. EBRON-MCCOY

In Vivo and in Vitro Structure-Dosimetry-Activity Relationships of Substituted Phenols in Developmental Toxicity Assays
Toxicol. Sci. 1991 16: 225-229; doi:10.1093/toxsci/16.2.225 [PDF] [Request Permissions]  

JOHAN L. GABRIELSSON

Utilization of Physiologically Based Models in Extrapolating Pharmacokinetic Data among Species
Toxicol. Sci. 1991 16: 230-232; doi:10.1093/toxsci/16.2.230 [PDF] [Request Permissions]  

DAVID E. MOODY, JANARDAN K. REDDY, BRIAN G. LAKE, JAMES A. POPP, and DAVID H. REESE

Peroxisome Proliferation and Nongenotoxic Carcinogenesis: Commentary on a Symposium
Toxicol. Sci. 1991 16: 233-248; doi:10.1093/toxsci/16.2.233 [PDF] [Request Permissions]  

MARISOL POCINO, LESLIE BAUTE, and INÉS MALAVÉ

Influence of the Oral Administration of Excess Copper on the Immune Response
Toxicol. Sci. 1991 16: 249-256; doi:10.1093/toxsci/16.2.249 [Abstract] [PDF] [Request Permissions]  

MICHAEL F. OBASAJU, DAVID F. KATZ, and MARION G. MILLER

Species Differences in Susceptibility to 1,3-Dinitrobenzene-lnduced Testicular Toxicity and Methemoglobinemia
Toxicol. Sci. 1991 16: 257-266; doi:10.1093/toxsci/16.2.257 [Abstract] [PDF] [Request Permissions]  

R. RAY, O. E. CLARK, III, K. W. FORD, K. R. KNIGHT, L. W. HARRIS, and C. A. BROOMFIELD

A Novel Tertiary Pyridostigmine Derivative [3-N,N-Dimethylcarbamyloxy)-1-Methyl-³-Tetrahydropyridine]: Anticholinesterase Properties and Efficacy against Soman
Toxicol. Sci. 1991 16: 267-274; doi:10.1093/toxsci/16.2.267 [Abstract] [PDF] [Request Permissions]  

C. M. ZWICKL, K. S. COCKE, R. N. TAMURA, L. M. HOLZHAUSEN, G. T. BROPHY, P. H. BICK, and D. WIERDA

Comparison of the Immunogenicity of Recombinant and Pituitary Human Growth Hormone in Rhesus Monkeys
Toxicol. Sci. 1991 16: 275-287; doi:10.1093/toxsci/16.2.275 [Abstract] [PDF] [Request Permissions]  

M. GLIKSON, A. ACHIRON, Z. RAM, A. AYALON, A. KARNI, I. SAROVA-PINCHAS, J. GLOVINSKI, and M. REVAH

The Influence of Pyridostigmine Administration on Human Neuromuscular Functions—Studies in Healthy Human Subjects
Toxicol. Sci. 1991 16: 288-298; doi:10.1093/toxsci/16.2.288 [Abstract] [PDF] [Request Permissions]  

STEVEN G. GILBERT and DEBORAH C. RICE

Effects of Chronic Caffeine Consumption in Pregnant Monkeys (Macaca fascicularis) on Blood and Urine Clinical Chemistry Parameters
Toxicol. Sci. 1991 16: 299-308; doi:10.1093/toxsci/16.2.299 [Abstract] [PDF] [Request Permissions]  

MICHELLE SCHAPER and KATHERINE DETWILER

Evaluation of the Acute Respiratory Effects of Aerosolized Machining Fluids in Mice
Toxicol. Sci. 1991 16: 309-319; doi:10.1093/toxsci/16.2.309 [Abstract] [PDF] [Request Permissions]  

R. J. GERSON, H. L. ALLEN, G. R. LANKAS, J. S. MACDONALD, A. W. ALBERTS, and D. L. BOKELMAN

The Toxicity of a Fluorinated-Biphenyl HMG-CoA Reductase Inhibitor in Beagle Dogs
Toxicol. Sci. 1991 16: 320-329; doi:10.1093/toxsci/16.2.320 [Abstract] [PDF] [Request Permissions]  

P. GERDE, Y. S. CHENG, and M. A. MEDINSKY

In VivoDeposition of Ultrafine Aerosols in the Nasal Airway of the Rat
Toxicol. Sci. 1991 16: 330-336; doi:10.1093/toxsci/16.2.330 [Abstract] [PDF] [Request Permissions]  

ANTHONY B. DEANGELO, F. BERNARD DANIEL, JUDY A. STOBER, and GREG R. OLSON

The Carcinogenicity of Dichloroacetic Acid in the Male B6C3F₁ Mouse
Toxicol. Sci. 1991 16: 337-347; doi:10.1093/toxsci/16.2.337 [Abstract] [PDF] [Request Permissions]  

DEBORAH D. GIERA and ROBERT B. L. VAN LIER

A Convenient Method for the Determination of Hepatic Laurie Acid -Oxidation Based on Solvent Partition
Toxicol. Sci. 1991 16: 348-355; doi:10.1093/toxsci/16.2.348 [Abstract] [PDF] [Request Permissions]  

AHMED E. AHMED, G. A. S. ANSARI, LENNART LENNART, and SVEN ULLBERG

Differential Distribution and Placental Transport of 2- and 3-t-[methy/-¹⁴C]Butyl-4-hydroxyanisole(BHA) in Pregnant Mice
Toxicol. Sci. 1991 16: 356-364; doi:10.1093/toxsci/16.2.356 [Abstract] [PDF] [Request Permissions]  

REGULAR ARTICLES:

C.-J. JONSSON, H. RODRIGUEZ-MARTINEZ, B.-O. LUND, A. BERGMAN, and I. BRANDT

Adrenocortical Toxicity of 3-Methylsulfonyl-DDE in Mice: II. Mitochondrial Changes following Ecologically Relevant Doses
Toxicol. Sci. 1991 16: 365-374; doi:10.1093/toxsci/16.2.365 [Abstract] [PDF] [Request Permissions]  

STEN FLODSTRÖM, LEIF BUSK, TONY KRONEVI, and ULF G. AHLBORG

Modulation of 2,3,7,8-Tetrachlorodibenzo-p-dioxin and Phenobarbital Induced Promotion of Hepatocarcinogenesis in Rats by the Type of Diet and Vitamin A Deficiency
Toxicol. Sci. 1991 16: 375-391; doi:10.1093/toxsci/16.2.375 [Abstract] [PDF] [Request Permissions]  

ANNOUNCEMENT:

ANNOUNCEMENT: Mid-America Toxicology Course
Toxicol. Sci. 1991 16: 392; doi:10.1093/toxsci/16.2.392 [PDF] [Request Permissions]  

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