Toxicological Sciences

WORKSHOP OVERVIEW:

J. R. BUCHER, C. J. PORTIER, J. I. GOODMAN, E. M. FAUSTMAN, and G. W. LUCIER

National Toxicology Program Studies: Principles of Dose Selection and Applications to Mechanistic Based Risk Assessment
Toxicol. Sci. 1996 31: 1-8; doi:10.1093/toxsci/31.1.1 [Abstract] [PDF] [Request Permissions]  

REGULAR ARTICLES:

MARY A. PERKINS, ROSEMARIE OSBORNE, and GARY R. JOHNSON

Development of an in Vitro Method for Skin Corrosion Testing
Toxicol. Sci. 1996 31: 9-18; doi:10.1093/toxsci/31.1.9 [Abstract] [PDF] [Request Permissions]  

RUSSELL S. THOMAS, WILLIAM E. LYTLE, THOMAS J. KEEFE, ALEXANDER A. CONSTAN, and RAYMOND S. H. YANG

Incorporating Monte Carlo Simulation into Physiologically Based Pharmacokinetic Models Using Advanced Continuous Simulation Language (ACSL): A Computational Method
Toxicol. Sci. 1996 31: 19-28; doi:10.1093/toxsci/31.1.19 [Abstract] [PDF] [Request Permissions]  

B. D. ASTILL, R. GINGELL, D. GUEST, J. HELLWIG, J. R. HODGSON, K. KUETTLER, W. MELLERT, S. R. MURPHY, R. L. SIELKEN, JR., and T. R. TYLER

Oncogenicity Testing of 2-Ethylhexanol in Fischer 344 Rats and B6C3F1 Mice
Toxicol. Sci. 1996 31: 29-41; doi:10.1093/toxsci/31.1.29 [Abstract] [PDF] [Request Permissions]  

D. L. ARNOLD, E. A. NERA, R. STAPLEY, G. TOLNAI, P. CLAMAN, S. HAYWARD, H. TRYPHONAS, and F. BRYCE

Prevalence of Endometriosis in Rhesus (Macaca mulatta) Monkeys Ingesting PCB (Aroclor 1254): Review and Evaluation
Toxicol. Sci. 1996 31: 42-55; doi:10.1093/toxsci/31.1.42 [Abstract] [PDF] [Request Permissions]  

M. J. WIESTER, J. S. TEPPER, D. W. WINSETT, K. M. CRISSMAN, J. H. RICHARDS, and D. L. COSTA

Adaptation to Ozone in Rats and Its Association with Ascorbic Acid in the Lung
Toxicol. Sci. 1996 31: 56-64; doi:10.1093/toxsci/31.1.56 [Abstract] [PDF] [Request Permissions]  

MATTHEW I. GILMOUR, PATRICIA PARK, and MARYJANE K. SELGRADE

Increased Immune and Inflammatory Responses to Dust Mite Antigen in Rats Exposed to 5 ppm NO₂
Toxicol. Sci. 1996 31: 65-70; doi:10.1093/toxsci/31.1.65 [Abstract] [PDF] [Request Permissions]  

MICHAEL H. ABRAHAM, JENIK ANDONIAN-HAFTVAN, J. ENRIQUE COMETTO-MUNIZ, and WILLIAM S. CAIN

An Analysis of Nasal Irritation Thresholds Using a New Solvation Equation
Toxicol. Sci. 1996 31: 71-76; doi:10.1093/toxsci/31.1.71 [Abstract] [PDF] [Request Permissions]  

ERIC W. AUSTIN, JEFF M. PARRISH, DAVID H. KINDER, and RICHARD J. BULL

Lipid Peroxidation and Formation of 8-Hydroxydeoxyguanosine from Acute Doses of Halogenated Acetic Acids
Toxicol. Sci. 1996 31: 77-82; doi:10.1093/toxsci/31.1.77 [Abstract] [PDF] [Request Permissions]  

G. W. VAN DER MOLEN, S. A. L. M. KOOIJMAN, and W. SLOB

A Generic Toxicokinetic Model for Persistent Lipophilic Compounds in Humans: An Application to TCDD
Toxicol. Sci. 1996 31: 83-94; doi:10.1093/toxsci/31.1.83 [Abstract] [PDF] [Request Permissions]  

ZAID JAYYOSI, MARGARET MUC, JOANNE ERICK, PAUL E. THOMAS, and MICHAEL KELLEY

Catalytic and Immunochemical Characterization of Cytochrome P450 Isozyme Induction in Dog Liver
Toxicol. Sci. 1996 31: 95-102; doi:10.1093/toxsci/31.1.95 [Abstract] [PDF] [Request Permissions]  

MERCEDES CASANOVA, RORY B. CONOLLY, and HENRY D'A. HECK

DNA—Protein Cross-Links (DPX) and Cell Proliferation in B6C3F₁ Mice but Not Syrian Golden Hamsters Exposed to Dichloromethane: Pharmacokinetics and Risk Assessment with DPX as Dosimeter
Toxicol. Sci. 1996 31: 103-116; doi:10.1093/toxsci/31.1.103 [Abstract] [PDF] [Request Permissions]  

A. B. LIBERACKI, T. L. NEEPER-BRADLEY, W. J. BRESLIN, and G. J. ZIELKE

Evaluation of the Developmental Toxicity of Dermally Applied Monoethanolamine in Rats and Rabbits
Toxicol. Sci. 1996 31: 117-123; doi:10.1093/toxsci/31.1.117 [Abstract] [PDF] [Request Permissions]  

FRANK A. WITZMANN, CARLA D. FULTZ, RAJA S. MANGIPUDY, and HARIHARA M. MEHENDALE

Two-Dimensional Electrophoretic Analysis of Compartment-Specific Hepatic Protein Charge Modification Induced by Thioacetamide Exposure in Rats
Toxicol. Sci. 1996 31: 124-132; doi:10.1093/toxsci/31.1.124 [Abstract] [PDF] [Request Permissions]  

KOHJI SHIMODA, MAMORU NOMURA, and MICHIYUKI KATO

Effect of Antioxidants, Anti-inflammatory Drugs, and Histamine Antagonists on Sparfloxacin-Induced Phototoxicity in Mice
Toxicol. Sci. 1996 31: 133-140; doi:10.1093/toxsci/31.1.133 [Abstract] [PDF] [Request Permissions]  

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