Toxicological Sciences

SYMPOSIUM: THE FUTURE OF ANIMALS IN RESEARCH AND TEACHING:

GORDON W. NEWELL

Introductory Comments
Toxicol. Sci. 1984 4: 503-504; doi:10.1093/toxsci/4.4.503 [PDF] [Request Permissions]  

CAROL F. RODGERS

Current Legislation for Development of Substitutes for Animals in Research
Toxicol. Sci. 1984 4: 505-507; doi:10.1093/toxsci/4.4.505 [PDF] [Request Permissions]  

ANDREW N. ROWAN

The Search for Alternatives
Toxicol. Sci. 1984 4: 508-516; doi:10.1093/toxsci/4.4.508 [Abstract] [PDF] [Request Permissions]  

ALAN M. GOLDBERG

The Johns Hopkins Center for Alternatives to Animal Testing
Toxicol. Sci. 1984 4: 517-518; doi:10.1093/toxsci/4.4.517 [Abstract] [PDF] [Request Permissions]  

I. F. H. PURCHASE

The European Scene
Toxicol. Sci. 1984 4: 519-530; doi:10.1093/toxsci/4.4.519 [Abstract] [PDF] [Request Permissions]  

REGULAR ARTICLES:

SUBBIAH P. SIVAM, BETH HOSKINS, and ING K. HO

An Assessment of Comparative Acute Toxicity of Diisopropylfluorophosphate, Tabun, Sarin, and Soman in Relation to Cholinergic and GABAergic Enzyme Activities in Rats
Toxicol. Sci. 1984 4: 531-538; doi:10.1093/toxsci/4.4.531 [Abstract] [PDF] [Request Permissions]  

RAYMOND S. H. YANG, R. H. GARMAN, E. V. WEAVER, and M. D. WOODSIDE

Two-Generation Reproduction Study of Ethylenediamine in Fischer 344 Rats
Toxicol. Sci. 1984 4: 539-546; doi:10.1093/toxsci/4.4.539 [Abstract] [PDF] [Request Permissions]  

I. CHU, D. C. VILLENEUVE, V. E. SECOURS, A. YAGMINAS, B. REED, and V. E. VALLI

Octachlorostyrene: A 90-Day Toxicity Study in the Rat
Toxicol. Sci. 1984 4: 547-557; doi:10.1093/toxsci/4.4.547 [Abstract] [PDF] [Request Permissions]  

R. G. SLIGHTER, M. J. MONTENARO, R. J. FABIAN, J. C. BHANDARI, M. R. DONIKIAN, and H. P. DROBECK

Comparative Nephrotoxidty of Hydroxygentamicin and Other Aminoglyoosides in Rats
Toxicol. Sci. 1984 4: 558-567; doi:10.1093/toxsci/4.4.558 [Abstract] [PDF] [Request Permissions]  

RALPH G. SLIGHTER, RAYMOND J. FABIAN, MARC R. DONIKIAN, RICHARD D. RENCH, MICHAEL J. NEIDL, and CHARLES R. BOSHART

Nephrotoxic and Ototoxic Effects of Hydroxygentamicin in Cats
Toxicol. Sci. 1984 4: 568-576; doi:10.1093/toxsci/4.4.568 [Abstract] [PDF] [Request Permissions]  

C. M. PARKER, V. J. PICCIRILLO, S. L. KURTZ, F. M. GARNER, T. H. GARDINER, and G. A. VAN GELDER

Six-Month Feeding Study of Fenvalerate in Dogs
Toxicol. Sci. 1984 4: 577-586; doi:10.1093/toxsci/4.4.577 [Abstract] [PDF] [Request Permissions]  

PETER J. BECCI, ELIZABETH L. REAGAN, JOHN H. WEDIG, and STEVEN J. BARBEE

Teratogenesis Study of N-Cyclohexyl-2-pyrrolidone in Rats Rabbits
Toxicol. Sci. 1984 4: 587-593; doi:10.1093/toxsci/4.4.587 [Abstract] [PDF] [Request Permissions]  

W. T. STOTT and M. J. MCKENNA

The Comparative Absorption and Excretion of Chemical Vapors by the Upper, Lower, and Intact Respiratory Tract of Rats
Toxicol. Sci. 1984 4: 594-602; doi:10.1093/toxsci/4.4.594 [Abstract] [PDF] [Request Permissions]  

GERALD L. KENNEDY, JR.

Acute and Environmental Toxicity Studies with Hexazinone
Toxicol. Sci. 1984 4: 603-611; doi:10.1093/toxsci/4.4.603 [Abstract] [PDF] [Request Permissions]  

TIMOTHY D. LANDRY and BARRY L. YANO

Dipropylene Glycol Monomethyl Ether: A 13-Week Inhalation Toxicity Study in Rats and Rabbits
Toxicol. Sci. 1984 4: 612-617; doi:10.1093/toxsci/4.4.612 [Abstract] [PDF] [Request Permissions]  

J. C. DOUSSET, C. RIOUFOL, R. FELISTE, P. LÉVY, and P. BOURBON

Effects of Inhaled HF on Lipid Metabolism in Guinea Pigs
Toxicol. Sci. 1984 4: 618-623; doi:10.1093/toxsci/4.4.618 [Abstract] [PDF] [Request Permissions]  

TAI L. CHAN, PETER S. LEE, and WILLIAM E. HERING

Pulmonary Retention of Inhaled Diesel Particles after Prolonged Exposures to Diesel Exhaust
Toxicol. Sci. 1984 4: 624-631; doi:10.1093/toxsci/4.4.624 [Abstract] [PDF] [Request Permissions]  

S. STANLEY YOUNG and CHRISTIAN L. GRIES

Exploration of the Negative Correlation between Proliferative Hepatocellular Lesions and Lymphoma in Rats and Mice—Establishment and Implications
Toxicol. Sci. 1984 4: 632-640; doi:10.1093/toxsci/4.4.632 [Abstract] [PDF] [Request Permissions]  

LINVAL R. DEPASS, EDWARD H. FOWLER, and RAYMOND S. H. YANG

Dermal Oncogenicity Studies on Ethyienediamine in Male C3H Mice
Toxicol. Sci. 1984 4: 641-645; doi:10.1093/toxsci/4.4.641 [Abstract] [PDF] [Request Permissions]  

BARRY H. THOMAS, LARRY W. WHITEHOUSE, and WALTER ZEITZ

Metabolism of [¹⁴C]Acetylisoniazid and [¹⁴C]Acetylhydrazine by the Rat and Rabbit
Toxicol. Sci. 1984 4: 646-653; doi:10.1093/toxsci/4.4.646 [Abstract] [PDF] [Request Permissions]  

RICHARD J. NOLAN, NANCY L. FRESHOUR, DAVID L. RICK, LESLIE P. MCCARTY, and JAMES H. SAUNDERS

Kinetics and Metabolism of Inhaled Methyl Chloroform (1,1,1-Trichloroethane) in Male Volunteers
Toxicol. Sci. 1984 4: 654-662; doi:10.1093/toxsci/4.4.654 [Abstract] [PDF] [Request Permissions]  

RAYMOND S. H. YANG, MARILYN J. TALLANT, and JOHN A. MCKELVEY

Age-Dependent Pharmacokinetic Changes of Ethylenediamine in Fischer 344 Rats Parallel to a Two-Year Chronic Toxicity Study
Toxicol. Sci. 1984 4: 663-670; doi:10.1093/toxsci/4.4.663 [Abstract] [PDF] [Request Permissions]  

ANNOUNCEMENT:

ANNOUNCEMENT
Toxicol. Sci. 1984 4: 671; doi:10.1093/toxsci/4.4.671 [PDF] [Request Permissions]  

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