Toxicological Sciences

Biotransformation and Toxicokinetics:

Christopher H. Hurst, Barbara D. Abbott, Michael J. DeVito, and Linda S. Birnbaum

2,3,7,8-Tetrachlorodibenzo-p-dioxin in Pregnant Long Evans Rats: Disposition to Maternal and Embryo/Fetal Tissues
Toxicol. Sci. 1998 45: 129-136; doi:10.1093/toxsci/45.2.129 [Abstract] [PDF] [Request Permissions]  

Carcinogenicity:

Earl F. Walborg, Jr., John DiGiovanni, Claudio J. Conti, Thomas J. Slaga, James J. Freeman, David R. Steup, and Christopher M. Skisak

Short-Term Biomarkers of Tumor Promotion in Mouse Skin Treated with Petroleum Middle Distillates
Toxicol. Sci. 1998 45: 137-145; doi:10.1093/toxsci/45.2.137 [Abstract] [PDF] [Request Permissions]  

J. H. McGee, W. H. Butler, D. J. Erikson, and R. D. Sofia

Oncogenic Studies with Felbamate (2-Phenyl-1,3-propanediol Dicarbamate)
Toxicol. Sci. 1998 45: 146-151; doi:10.1093/toxsci/45.2.146 [Abstract] [PDF] [Request Permissions]  

G. M. Williams, M. J. Iatropoulos, C. X. Wang, A. M. Jeffrey, S. Thompson, B. Pittman, M. Palasch, and R. Gebhardt

Nonlinearities in 2-Acetylaminofluorene Exposure Responses for Genotoxic and Epigenetic Effects Leading to Initiation of Carcinogenesis in Rat Liver
Toxicol. Sci. 1998 45: 152-161; doi:10.1093/toxsci/45.2.152 [Abstract] [PDF] [Request Permissions]  

Endocrine Toxicology:

Li You, Mercedes Casanova, Shannon Archibeque-Engle, Madhabananda Sar, Li-Qun Fan, and Henry d'A. Heck

Impaired Male Sexual Development in Perinatal Sprague-Dawley and Long-Evans Hooded Rats Exposed in Utero and Lactationally to p,p'-DDE
Toxicol. Sci. 1998 45: 162-173; doi:10.1093/toxsci/45.2.162 [Abstract] [PDF] [Request Permissions]  

Hugh A. Barton and Melvin E. Andersen

A Model for Pharmacokinetics and Physiological Feedback among Hormones of the Testicular-Pituitary Axis in Adult Male Rats: A Framework for Evaluating Effects of Endocrine Active Compounds
Toxicol. Sci. 1998 45: 174-187; doi:10.1093/toxsci/45.2.174 [Abstract] [PDF] [Request Permissions]  

A. Gerlienke Schuur, Ingeborg van Leeuwen-Bol, Willeke M. C. Jong, Åke Bergman, Michael W. H. Coughtrie, Abraham Brouwer, and Theo J. Visser

In Vitro Inhibition of Thyroid Hormone Sulfation by Polychlorobiphenylols: Isozyme Specificity and Inhibition Kinetics
Toxicol. Sci. 1998 45: 188-194; doi:10.1093/toxsci/45.2.188 [Abstract] [PDF] [Request Permissions]  

Immunotoxicology:

Marsha D. W. Ward, Denise M. Sailstad, and MaryJane K. Selgrade

Allergic Responses to the Biopesticide Metarhizium anisopliae in Balb/c Mice
Toxicol. Sci. 1998 45: 195-203; doi:10.1093/toxsci/45.2.195 [Abstract] [PDF] [Request Permissions]  

Mitsuru Shimizu, James F. Hochadel, Brandie A. Fulmer, and Michael P. Waalkes

Effect of Glutathione Depletion and Metallothionein Gene Expression on Arsenic-Induced Cytotoxicity and c-myc Expression in Vitro
Toxicol. Sci. 1998 45: 204-211; doi:10.1093/toxsci/45.2.204 [Abstract] [PDF] [Request Permissions]  

Reproductive and Developmental Toxicology:

A. M. Saillenfait, J. P. Payan, J. P. Fabry, D. Beydon, I. Langonne, F. Gallissot, and J. P. Sabate

Assessment of the Developmental Toxicity, Metabolism, and Placental Transfer of Di-n-butyl Phthalate Administered to Pregnant Rats
Toxicol. Sci. 1998 45: 212-224; doi:10.1093/toxsci/45.2.212 [Abstract] [PDF] [Request Permissions]  

Safety Evaluation:

J. H. McGee, D. J. Erikson, C. Galbreath, D. A. Willigan, and R. D. Sofia

Acute, Subchronic, and Chronic Toxicity Studies with Felbamate, 2-Phenyl-1,3-propanediol Dicarbamate
Toxicol. Sci. 1998 45: 225-232; doi:10.1093/toxsci/45.2.225 [Abstract] [PDF] [Request Permissions]  

Systems Toxicology:

Shashi K. Ramaiah, Thomas J. Bucci, Alan Warbritton, Madhusudan G. Soni, and Harihara M. Mehendale

Temporal Changes in Tissue Repair Permit Survival of Diet-Restricted Rats from an Acute Lethal Dose of Thioacetamide
Toxicol. Sci. 1998 45: 233-241; doi:10.1093/toxsci/45.2.233 [Abstract] [PDF] [Request Permissions]  

R. Demnati, R. Fraser, J. G. Martin, G. Plaa, and J. L. Malo

Effects of Dexamethasone on Functional and Pathological Changes in Rat Bronchi Caused by High Acute Exposure to Chlorine
Toxicol. Sci. 1998 45: 242-246; doi:10.1093/toxsci/45.2.242 [Abstract] [PDF] [Request Permissions]  

Stan Spence, Keith Soper, Chao-Min Hoe, and John Coleman

The Heart Rate-Corrected QT Interval of Conscious Beagle Dogs: A Formula Based on Analysis of Covariance
Toxicol. Sci. 1998 45: 247-258; doi:10.1093/toxsci/45.2.247 [Abstract] [PDF] [Request Permissions]  

AUTHOR INDEX FOR VOLUME 45:

Author Index For Volume 45
Toxicol. Sci. 1998 45: 259; doi:10.1093/toxsci/45.2.259 [PDF] [Request Permissions]  

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