Toxicological Sciences

Biotransformation and Toxicokinetics:

Virginia C. Moser, Sushmita M. Chanda, Spencer R. Mortensen, and Stephanie Padilla

Age- and Gender-Related Differences in Sensitivity to Chlorpyrifos in the Rat Reflect Developmental Profiles of Esterase Activities
Toxicol. Sci. 1998 46: 211-222; doi:10.1093/toxsci/46.2.211 [Abstract] [PDF] [Request Permissions]  

Michael J. DeVito, David G. Ross, Aubry E. Dupuy, Jr., Joseph Ferrario, Danny McDaniel, and Linda S. Birnbaum

Dose–Response Relationships for Disposition and Hepatic Sequestration of Polyhalogenated Dibenzo-p-dioxins, Dibenzofurans, and Biphenyls Following Subchronic Treatment in Mice
Toxicol. Sci. 1998 46: 223-234; doi:10.1093/toxsci/46.2.223 [Abstract] [PDF] [Request Permissions]  

Matthew S. Bogdanffy, Ramesh Sarangapani, Julia S. Kimbell, S. Randall Frame, and David R. Plowchalk

Analysis of Vinyl Acetate Metabolism in Rat and Human Nasal Tissues by an in Vitro Gas Uptake Technique
Toxicol. Sci. 1998 46: 235-246; doi:10.1093/toxsci/46.2.235 [Abstract] [PDF] [Request Permissions]  

Ingvar A. Bergdahl, Marina Sheveleva, Andrejs Schütz, Volja G. Artamonova, and Staffan Skerfving

Plasma and Blood Lead in Humans: Capacity-Limited Binding to -Aminolevulinic Acid Dehydratase and Other Lead-Binding Components
Toxicol. Sci. 1998 46: 247-253; doi:10.1093/toxsci/46.2.247 [Abstract] [PDF] [Request Permissions]  

Lynda S. Wright, Steven E. Kornguth, Terry D. Oberley, and Frank L. Siegel

Effects of Lead on Glutathione S-Transferase Expression in Rat Kidney: A Dose—Response Study
Toxicol. Sci. 1998 46: 254-259; doi:10.1093/toxsci/46.2.254 [Abstract] [PDF] [Request Permissions]  

Carcinogenicity:

Jatinder Singh, John A. McLean, Daryl E. Pritchard, Akbar Montaser, and Steven R. Patierno

Sensitive Quantitation of Chromium-DNA Adducts by Inductively Coupled Plasma Mass Spectrometry with a Direct Injection High-Efficiency Nebulizer
Toxicol. Sci. 1998 46: 260-265; doi:10.1093/toxsci/46.2.260 [Abstract] [PDF] [Request Permissions]  

George Cruzan, Janette R. Cushman, Larry S. Andrews, Geoffrey C. Granville, Keith A. Johnson, Colin J. Hardy, Derek W. Coombs, Pamela A. Mullins, and W. Ray Brown

Chronic Toxicity/Oncogenicity Study of Styrene in CD Rats by Inhalation Exposure for 104 Weeks
Toxicol. Sci. 1998 46: 266-281; doi:10.1093/toxsci/46.2.266 [Abstract] [PDF] [Request Permissions]  

Endocrine Toxicology:

T. R. Zacharewski, M. D. Meek, J. H. Clemons, Z. F. Wu, M. R. Fielden, and J. B. Matthews

Examination of the in Vitro and in VitroEstrogenic Activities of Eight Commercial Phthalate Esters
Toxicol. Sci. 1998 46: 282-293; doi:10.1093/toxsci/46.2.282 [Abstract] [PDF] [Request Permissions]  

Lorelle L. Bestervelt, Jeff A. Pitt, and Walter N. Piper

Evidence for Ah Receptor Mediation of Increased ACTH Concentrations in Primary Cultures of Rat Anterior Pituitary Cells Exposed to TCDD
Toxicol. Sci. 1998 46: 294-299; doi:10.1093/toxsci/46.2.294 [Abstract] [PDF] [Request Permissions]  

Immunotoxicology:

C. J. Johnston, J. N. Finkelstein, R. Gelein, and G. Oberdörster

Pulmonary Cytokine and Chemokine mRNA Levels after Inhalation of Lipopolysaccharide in C57BL/6 Mice
Toxicol. Sci. 1998 46: 300-307; doi:10.1093/toxsci/46.2.300 [Abstract] [PDF] [Request Permissions]  

Alan P. Brown, Jesus Olivero-Verbel, Wendy L. Holdan, and Patricia E. Ganey

Neutrophil Activation by Polychlorinated Biphenyls: Structure—Activity Relationship
Toxicol. Sci. 1998 46: 308-316; doi:10.1093/toxsci/46.2.308 [Abstract] [PDF] [Request Permissions]  

Molecular and Genetic Toxicology:

Steven K. Duddy, Suzanne Gorospe, and Michael R. Bleavins

Genetic Analysis of Multiple Loci in Microsamples of Fixed Paraffin-Embedded Tissue
Toxicol. Sci. 1998 46: 317-323; doi:10.1093/toxsci/46.2.317 [Abstract] [PDF] [Request Permissions]  

P. J. Ciaccio, E. Gicquel, P. J. O'Neill, H. E. Scribner, and Y. L. Vandenberghe

Investigation of the Positive Response of Ethyl Acrylate in the Mouse Lymphoma Genotoxicity Assay
Toxicol. Sci. 1998 46: 324-332; doi:10.1093/toxsci/46.2.324 [Abstract] [PDF] [Request Permissions]  

Neurotoxicology:

Jiazhong Jiang, Yong Xu, and James E. Klaunig

Induction of Oxidative Stress in Rat Brain by Acrylonitrile (ACN)
Toxicol. Sci. 1998 46: 333-341; doi:10.1093/toxsci/46.2.333 [Abstract] [PDF] [Request Permissions]  

Jennifer Holmes, Jason Stanko, Maria Varchenko, Hong Ding, Victoria J. Madden, C. Robert Bagnell, Steven D. Wyrick, and Stephen G. Chaney

Comparative Neurotoxicity of Oxaliplatin, Cisplatin, and Ormaplatin in a Wistar Rat Model
Toxicol. Sci. 1998 46: 342-351; doi:10.1093/toxsci/46.2.342 [Abstract] [PDF] [Request Permissions]  

Risk Assessment:

Lilian Calderón-Garcidueñas, Antonio Rodríguez-Alcaraz, Anna Villarreal-Calderón, Otis Lyght, Derek Janszen, and Kevin T. Morgan

Nasal Epithelium as a Sentinel for Airborne Environmental Pollution
Toxicol. Sci. 1998 46: 352-364; doi:10.1093/toxsci/46.2.352 [Abstract] [PDF] [Request Permissions]  

Safety Evaluation:

D. K. Monteith, R. S. Geary, J. M. Leeds, J. Johnston, B. P. Monia, and A. A. Levin

Preclinical Evaluation of the Effects of a Novel Antisense Compound Targeting C-raf Kinase in Mice and Monkeys
Toxicol. Sci. 1998 46: 365-375; doi:10.1093/toxsci/46.2.365 [Abstract] [PDF] [Request Permissions]  

Systems Toxicology:

Niel C. Hoglen, Husam S. Younis, Dylan P. Hartley, Lhanoo Gunawardhana, R. Clark Lantz, and I. Glenn Sipes

1,2-Dichlorobenzene-lnduced Lipid Peroxidation in Male Fischer 344 Rats is Kupffer Cell Dependent
Toxicol. Sci. 1998 46: 376-385; doi:10.1093/toxsci/46.2.376 [Abstract] [PDF] [Request Permissions]  

D. J. Conklin, S. D. Langford, and P. J. Boor

Contribution of Serum and Cellular Semicarbazide-Sensitive Amine Oxidase to Amine Metabolism and Cardiovascular Toxicity
Toxicol. Sci. 1998 46: 386-392; doi:10.1093/toxsci/46.2.386 [Abstract] [PDF] [Request Permissions]  

Tetsuo Yamano, Mitsuru Shimizu, and Tsutomu Noda

Comparative Effects of Repeated Administration of Cadmium on Kidney, Spleen, Thymus, and Bone Marrow in 2-, 4-, and 8-Month-Old Male Wistar Rats
Toxicol. Sci. 1998 46: 393-402; doi:10.1093/toxsci/46.2.393 [Abstract] [PDF] [Request Permissions]  

Vandana S. Poovala, Vijaya K. Kanji, Hiroyasu Tachikawa, and Abdulla K. Salahudeen

Role of Oxidant Stress and Antioxidant Protection in Acephate-Induced Renal Tubular Cytotoxicity
Toxicol. Sci. 1998 46: 403-409; doi:10.1093/toxsci/46.2.403 [Abstract] [PDF] [Request Permissions]  

Khandoker M. Morshed, Sushil K. Jain, and Kenneth E. McMartin

Propylene Glycol-Mediated Cell Injury in a Primary Culture of Human Proximal Tubule Cells
Toxicol. Sci. 1998 46: 410-417; doi:10.1093/toxsci/46.2.410 [Abstract] [PDF] [Request Permissions]  

LETTERS TO THE EDITORS:

Kim Boekelheide

LETTERS TO THE EDITORS
Toxicol. Sci. 1998 46: 418-419; doi:10.1093/toxsci/46.2.418 [PDF] [Request Permissions]  

Philip G. Watanabe

reply
Toxicol. Sci. 1998 46: 419; doi:10.1093/toxsci/46.2.419-a [PDF] [Request Permissions]  

AUTHOR INDEX FOR VOLUME 46:

Author Index for Volume 46
Toxicol. Sci. 1998 46: 421-422; doi:10.1093/toxsci/46.2.421 [PDF] [Request Permissions]  

CUMULATIVE AUTHOR INDEX FOR VOLUMES 4146:

Cumulative Author Index for Volumes 41–46
Toxicol. Sci. 1998 46: 423-426; doi:10.1093/toxsci/46.2.423 [PDF] [Request Permissions]  

CUMULATIVE SUBJECT INDEX FOR VOLUMES 4146:

Cumulative Subject Index for Volumes 41–46
Toxicol. Sci. 1998 46: 427-442; doi:10.1093/toxsci/46.2.427 [PDF] [Request Permissions]  

CUMULATIVE CHEMICAL INDEX FOR VOLUMES 4146:

Cumulative Chemical Index for Volumes 41–46
Toxicol. Sci. 1998 46: 443-444; doi:10.1093/toxsci/46.2.443 [PDF] [Request Permissions]  

ERRATA:

ERRATUM
Toxicol. Sci. 1998 46: 419; doi:10.1093/toxsci/46.2.419 [Abstract] [PDF] [Request Permissions]  

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