Cover illustration. Structurally related to serotonin, melatonin, and harmaline, ibogaine produces distinctive bands of degenerating cerebellar Purkinje neurons (upper left panel, with silver stain). Similar bands are revealed either as darker zones of GFAP immunoreactive Bergmann glia among more highly staining astrocytes (upper right panel), or as regions lacking calbindin immunoreactive Purkinje neurons (lower left panel). See the article by Xu et al., pp. 95-101.
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