Toxicological Sciences

Toxicological Highlight:

Harihara M. Mehendale

PPAR-: A Key to the Mechanism of Hepatoprotection by Clofibrate
Toxicol. Sci. 2000 57: 187-190; doi:10.1093/toxsci/57.2.187 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Profiles in Toxicology:

David L. Eaton and Lucio G. Costa

Sheldon D. Murphy
Toxicol. Sci. 2000 57: 191-192; doi:10.1093/toxsci/57.2.191 [Extract] [FREE Full Text] [PDF] [Request Permissions]  

Forum:

T. Narahashi, C. P. Fenster, M. W. Quick, R. A. J. Lester, W. Marszalec, G. L. Aistrup, D. B. Sattelle, B. R. Martin, and E. D. Levin

Symposium Overview: Mechanism of Action of Nicotine on Neuronal Acetylcholine Receptors, from Molecule to Behavior
Toxicol. Sci. 2000 57: 193-202; doi:10.1093/toxsci/57.2.193 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Carcinogenicity:

Peter J. Boogaard, Kees P. de Kloe, Brian A. Wong, Susan C. J. Sumner, William P. Watson, and Nico J. van Sittert

Quantification of DNA Adducts Formed in Liver, Lungs, and Isolated Lung Cells of Rats and Mice Exposed to ¹⁴C-Styrene by Nose-Only Inhalation
Toxicol. Sci. 2000 57: 203-216; doi:10.1093/toxsci/57.2.203 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Tracy L. Weimer, Ashok P. Reddy, Ulrich Harttig, David Alexander, S. Craig Stamm, Michael R. Miller, William Baird, Jerry Hendricks, and George Bailey

Influence of ß-Naphthoflavone on 7,12-Dimethylbenz(a)anthracene Metabolism, DNA Adduction, and Tumorigenicity in Rainbow Trout
Toxicol. Sci. 2000 57: 217-228; doi:10.1093/toxsci/57.2.217 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Environmental Toxicology:

Wade H. Powell, Rachel Bright, Susan M. Bello, and Mark E. Hahn

Developmental and Tissue-Specific Expression of AHR1, AHR2, and ARNT2 in Dioxin-Sensitive and -Resistant Populations of the Marine Fish Fundulus heteroclitus
Toxicol. Sci. 2000 57: 229-239; doi:10.1093/toxsci/57.2.229 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Molecular and Genetic Toxicology:

Thomas L. Horn, Arindam Bhattacharjee, Lawrence B. Schook, and Mark S. Rutherford

Altered Hepatic mRNA Expression of Apoptotic Genes during Dimethylnitrosamine Exposure
Toxicol. Sci. 2000 57: 240-249; doi:10.1093/toxsci/57.2.240 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Neurotoxicology:

Jacques P. J. Maurissen, Alan M. Hoberman, Robert H. Garman, and Thomas R. Hanley, Jr.

Lack of Selective Developmental Neurotoxicity in Rat Pups from Dams Treated by Gavage with Chlorpyrifos
Toxicol. Sci. 2000 57: 250-263; doi:10.1093/toxsci/57.2.250 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Reproductive and Developmental Toxicology:

Sigmund J. Degitz, Patricia A. Kosian, Elizabeth A. Makynen, Kathleen M. Jensen, and Gerald T. Ankley

Stage- and Species-Specific Developmental Toxicity of All-Trans Retinoic Acid in Four Native North American Ranids and Xenopus laevis
Toxicol. Sci. 2000 57: 264-274; doi:10.1093/toxsci/57.2.264 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Christopher H. Hurst, Michael J. DeVito, and Linda S. Birnbaum

Tissue Disposition of 2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) in Maternal and Developing Long-Evans Rats following Subchronic Exposure
Toxicol. Sci. 2000 57: 275-283; doi:10.1093/toxsci/57.2.275 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Julia D. George, Catherine J. Price, Melissa C. Marr, Christina B. Myers, and Gloria D. Jahnke

Evaluation of the Developmental Toxicity of Formamide in Sprague-Dawley (CD) Rats
Toxicol. Sci. 2000 57: 284-291; doi:10.1093/toxsci/57.2.284 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Hellmuth Lilienthal, Annemarie Fastabend, Jürgen Hany, Hatice Kaya, Astrid Roth-Härer, Lothar Dunemann, and Gerhard Winneke

Reduced Levels of 1,25-Dihydroxyvitamin D₃ in Rat Dams and Offspring after Exposure to a Reconstituted PCB Mixture
Toxicol. Sci. 2000 57: 292-301; doi:10.1093/toxsci/57.2.292 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

David L. Buchanan, Tomomi Sato, Richard E. Peterson, and Paul S. Cooke

Antiestrogenic Effects of 2,3,7,8-Tetrachlorodibenzo-p-dioxin in Mouse Uterus: Critical Role of the Aryl Hydrocarbon Receptor in Stromal Tissue
Toxicol. Sci. 2000 57: 302-311; doi:10.1093/toxsci/57.2.302 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Respiratory Toxicology:

Melvin Andersen, Ramesh Sarangapani, Robinan Gentry, Harvey Clewell, Tammie Covington, and Clay B. Frederick

Application of a Hybrid CFD-PBPK Nasal Dosimetry Model in an Inhalation Risk Assessment: An Example with Acrylic Acid
Toxicol. Sci. 2000 57: 312-325; doi:10.1093/toxsci/57.2.312 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Systems Toxicology:

Donald G. Robertson, Michael D. Reily, Robert E. Sigler, Dale F. Wells, David A. Paterson, and Timothy K. Braden

Metabonomics: Evaluation of Nuclear Magnetic Resonance (NMR) and Pattern Recognition Technology for Rapid in Vivo Screening of Liver and Kidney Toxicants
Toxicol. Sci. 2000 57: 326-337; doi:10.1093/toxsci/57.2.326 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Chuan Chen, Gayle E. Hennig, Herbert E. Whiteley, J. Christopher Corton, and José E. Manautou

Peroxisome Proliferator-Activated Receptor Alpha-Null Mice Lack Resistance to Acetaminophen Hepatotoxicity following Clofibrate Exposure
Toxicol. Sci. 2000 57: 338-344; doi:10.1093/toxsci/57.2.338 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Joseph M. Griffin, Kathleen M. Gilbert, Laura W. Lamps, and Neil R. Pumford

CD4⁺ T-Cell Activation and Induction of Autoimmune Hepatitis following Trichloroethylene Treatment in MRL+/+ Mice
Toxicol. Sci. 2000 57: 345-352; doi:10.1093/toxsci/57.2.345 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

To see an article, click its [Full Text] or [PDF] link. To review many abstracts, check the boxes to the left of the titles you want, and click the 'Get All Checked Abstract(s)' button. To see one abstract at a time, click its [Abstract] link.