Toxicological Sciences

ISSUES:

GEORGE L. FREDERICK

The Necessary Minimal Duration of Final Long-Term Toxicologic Tests of Drugs
Toxicol. Sci. 1986 6: 385-394; doi:10.1093/toxsci/6.3.385 [Abstract] [PDF] [Request Permissions]  

REGULAR ARTICLES:

CARLTON D. JACKSON and LAWRENCE FISHBEIN

A Toxicological Review of Beta-Adrenergic Blockers
Toxicol. Sci. 1986 6: 395-422; doi:10.1093/toxsci/6.3.395 [Abstract] [PDF] [Request Permissions]  

GERALD L. KENNEDY, JR.

Acute Toxicity Studies with Oxamyl
Toxicol. Sci. 1986 6: 423-429; doi:10.1093/toxsci/6.3.423 [Abstract] [PDF] [Request Permissions]  

BRYAN D. HARDIN, PHILLIP T. GOAD, and JEANN R. BURG

Developmental Toxicity of Diethylene Glycol Monomethyl Ether (diEGME)
Toxicol. Sci. 1986 6: 430-439; doi:10.1093/toxsci/6.3.430 [Abstract] [PDF] [Request Permissions]  

THOMAS F. BOOZE and FREDERICK W. OEHME

An Investigation of Metaldehyde and Acetaldehyde Toxicities in Dogs
Toxicol. Sci. 1986 6: 440-446; doi:10.1093/toxsci/6.3.440 [Abstract] [PDF] [Request Permissions]  

F. B. DANIEL, K. M. SCHENCK, J. K. MATTOX, E. L. C. LIN, D. L. HAAS, and M. A. PEREIRA

Genotoxic Properties of Haloacetonitriles: Drinking Water By-Products of Chlorine Disinfection
Toxicol. Sci. 1986 6: 447-453; doi:10.1093/toxsci/6.3.447 [Abstract] [PDF] [Request Permissions]  

ANTHONY P. DECAPRIO, DONALD N. MCMARTIN, PATRICK W. O'KEEFE, ROBERT REJ, JAY B. SILKWORTH, and LAURENCE S. KAMINSKY

Subchronic Oral Toxicity of 2,3,7,8-Tetrachlorodibenzo-p-dioxin in the Guinea Pig: Comparisons with a PCB-Containing Transformer Fluid Pyrolysate
Toxicol. Sci. 1986 6: 454-463; doi:10.1093/toxsci/6.3.454 [Abstract] [PDF] [Request Permissions]  

ROSANNE NOVAK and STEPHANIE PADILLA

An in Vitro Comparison of Rat and Chicken Brain Neurotoxic Esterase
Toxicol. Sci. 1986 6: 464-471; doi:10.1093/toxsci/6.3.464 [Abstract] [PDF] [Request Permissions]  

D. J. PAUSTENBACH, J. E. CHRISTIAN, G. P. CARLSON, and G. S. BORN

The Effect of an 11.5-hr/Day Exposure Schedule on the Distribution and Toxicity of Inhaled Carbon Tetrachloride in the Rat
Toxicol. Sci. 1986 6: 472-483; doi:10.1093/toxsci/6.3.472 [Abstract] [PDF] [Request Permissions]  

D. J. PAUSTENBACH, G. P. CARLSON, J. E. CHRISTIAN, and G. S. BORN

A Comparative Study of the Pharmacokinetics of Carbon Tetrachloride in the Rat following Repeated Inhalation Exposures of 8 and 11.5 hr/day
Toxicol. Sci. 1986 6: 484-497; doi:10.1093/toxsci/6.3.484 [Abstract] [PDF] [Request Permissions]  

GARY V. KATZ, EUGENE R. RENNER, JR., and C. J. TERHAAR

Subchronic Inhalation Toxicity of Methyl Isoamyl Ketone in Rats
Toxicol. Sci. 1986 6: 498-505; doi:10.1093/toxsci/6.3.498 [Abstract] [PDF] [Request Permissions]  

CHING-TANG SU, POU-HSIUNG WANG, RON-FE LIU, JIAU-HORNG SHIH, CHONG MA, CHUN-HSU LIN, CHONG-YEAN LIU, and MOU-THAI WU

Kinetic Studies and Structure—Activity Relationships of Bispyridinium Oximes as Reactivators of Acetylcholinesterase Inhibited by Organophosphorus Compounds
Toxicol. Sci. 1986 6: 506-514; doi:10.1093/toxsci/6.3.506 [Abstract] [PDF] [Request Permissions]  

CHRISTOPHER J. PORTIER

Type 1 Error and Power of the Linear Trend Test in Proportions under the National Toxicology Program's Modified Pathology Protocol
Toxicol. Sci. 1986 6: 515-519; doi:10.1093/toxsci/6.3.515 [Abstract] [PDF] [Request Permissions]  

J. E. FITZGERALD, J. A. PETRERE, E. J. MCGUIRE, and F. A. DE LA IGLESIA

Preclinical Toxicology Studies with the Lipid-Regulating Agent Gemcadiol
Toxicol. Sci. 1986 6: 520-531; doi:10.1093/toxsci/6.3.520 [Abstract] [PDF] [Request Permissions]  

YOU-YI LIANG, CAROLYN MARLOWE, and WILLIAM J. WADDELL

Disposition of [¹⁴C]Dimercaptosuccinic Acid in Mice
Toxicol. Sci. 1986 6: 532-540; doi:10.1093/toxsci/6.3.532 [Abstract] [PDF] [Request Permissions]  

CHIU-WING LAM, MERCEDES CASANOVA, and HENRY D'A. HECK

Decreased Extractability of DNA from Proteins in the Rat Nasal Mucosa after Acetaldehyde Exposure
Toxicol. Sci. 1986 6: 541-550; doi:10.1093/toxsci/6.3.541 [Abstract] [PDF] [Request Permissions]  

JOHN L. O'DONOGHUE

Subchronic Oral Toxicology of 4-Chloro-3-nitroaniline in the Rat
Toxicol. Sci. 1986 6: 551-558; doi:10.1093/toxsci/6.3.551 [Abstract] [PDF] [Request Permissions]  

DENNIS W. LYNCH, WILLIAM J. MOORMAN, PAUL STOBER, TRENT R. LEWIS, and WILLIAM O. IVERSON

Subchronic Inhalation of Diethylamine Vapor in Fischer-344 Rats: Organ System Toxicity
Toxicol. Sci. 1986 6: 559-565; doi:10.1093/toxsci/6.3.559 [Abstract] [PDF] [Request Permissions]  

SHARAD S. DESHPANDE, GLAUCE B. VIANA, FREDERICK C. KAUFFMAN, DANIEL L. RICKETT, and EDSON X. ALBUQUERQUE

Effectiveness of Physostigmine as a Pretreatment Drug for Protection of Rats from Organophosphate Poisoning
Toxicol. Sci. 1986 6: 566-567; doi:10.1093/toxsci/6.3.566 [Abstract] [PDF] [Request Permissions]  

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