Toxicological Sciences

TOXICOLOGICAL HIGHLIGHT:

Nikolay M. Filipov and David A. Lawrence

Developmental Toxicity of a Triazole Fungicide: Consideration of Interorgan Communication
Toxicol. Sci. 2001 62: 185-186; doi:10.1093/toxsci/62.2.185 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

PROFILES IN TOXICOLOGY:

Frederick W. Oehme

The Society of Toxicology's 1977 Actions on Laboratory Accreditation, Professional Certification, and Good Laboratory Practices in Toxicology
Toxicol. Sci. 2001 62: 187-190; doi:10.1093/toxsci/62.2.187 [Extract] [FREE Full Text] [PDF] [Request Permissions]  

BIOTRANSFORMATION AND TOXICOKINETICS:

Amy Collins Licata, Wolfgang Dekant, Charles E. Smith, and Susan J. Borghoff

A Physiologically Based Pharmacokinetic Model for Methyl tert-Butyl Ether in Humans: Implementing Sensitivity and Variability Analyses
Toxicol. Sci. 2001 62: 191-204; doi:10.1093/toxsci/62.2.191 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Tanja Bayer, Thomas Colnot, and Wolfgang Dekant

Disposition and Biotransformation of the Estrogenic Isoflavone Daidzein in Rats
Toxicol. Sci. 2001 62: 205-211; doi:10.1093/toxsci/62.2.205 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Tamara R. Knight, Angela Kurtz, Mary Lynn Bajt, Jack A. Hinson, and Hartmut Jaeschke

Vascular and Hepatocellular Peroxynitrite Formation during Acetaminophen Toxicity: Role of Mitochondrial Oxidant Stress
Toxicol. Sci. 2001 62: 212-220; doi:10.1093/toxsci/62.2.212 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Shin'ichi Yoshihara, Misako Makishima, Noriko Suzuki, and Shigeru Ohta

Metabolic Activation of Bisphenol A by Rat Liver S9 Fraction
Toxicol. Sci. 2001 62: 221-227; doi:10.1093/toxsci/62.2.221 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

CARCINOGENICITY:

T. M. Williams and S. J. Borghoff

Characterization of tert-Butyl Alcohol Binding to 2u-Globulin in F-344 Rats
Toxicol. Sci. 2001 62: 228-235; doi:10.1093/toxsci/62.2.228 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

ENDOCRINE TOXICOLOGY:

Barry S. McIntyre, Norman J. Barlow, and Paul M. D. Foster

Androgen-Mediated Development in Male Rat Offspring Exposed to Flutamide in Utero: Permanence and Correlation of Early Postnatal Changes in Anogenital Distance and Nipple Retention with Malformations in Androgen-Dependent Tissues
Toxicol. Sci. 2001 62: 236-249; doi:10.1093/toxsci/62.2.236 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Melanie S. Flint and Sally S. Tinkle

C57BL/6 Mice Are Resistant to Acute Restraint Modulation of Cutaneous Hypersensitivity
Toxicol. Sci. 2001 62: 250-256; doi:10.1093/toxsci/62.2.250 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

ENVIRONMENTAL TOXICOLOGY:

L. G. Parks, C. S. Lambright, E. F. Orlando, L. J. Guillette, Jr., G. T. Ankley, and L. E. Gray, Jr.

Masculinization of Female Mosquitofish in Kraft Mill Effluent-Contaminated Fenholloway River Water Is Associated with Androgen Receptor Agonist Activity
Toxicol. Sci. 2001 62: 257-267; doi:10.1093/toxsci/62.2.257 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Allen W. Olmstead and Gerald L. LeBlanc

Low Exposure Concentration Effects of Methoprene on Endocrine-Regulated Processes in the Crustacean Daphnia magna
Toxicol. Sci. 2001 62: 268-273; doi:10.1093/toxsci/62.2.268 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

NEUROTOXICOLOGY:

Angelo Moretto, Giulio Gardiman, Susi Panfilo, Marie-Anne Colle, Edward A. Lock, and Marcello Lotti

Effects of S-Ethyl Hexahydro-1H-azepine-1-carbothioate (Molinate) on Di-n-butyl Dichlorovinyl Phosphate (DBDCVP) Neuropathy
Toxicol. Sci. 2001 62: 274-279; doi:10.1093/toxsci/62.2.274 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Kyu-Yoon Hwang, Brian S. Schwartz, Byung-Kook Lee, Paul T. Strickland, Andy C. Todd, and Joseph P. Bressler

Associations of Lead Exposure and Dose Measures with Erythrocyte Protein Kinase C Activity in 212 Current Korean Lead Workers
Toxicol. Sci. 2001 62: 280-288; doi:10.1093/toxsci/62.2.280 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

REPRODUCTIVE AND DEVELOPMENTAL TOXICOLOGY:

Jeff A. Pitt, Li Feng, Barbara D. Abbott, Judy Schmid, Ronald E. Batt, Theodore G. Costich, Stephen T. Koury, and Diane P. Bofinger

Expression of AhR and ARNT mRNA in Cultured Human Endometrial Explants Exposed to TCDD
Toxicol. Sci. 2001 62: 289-298; doi:10.1093/toxsci/62.2.289 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Diane P. Bofinger, Li Feng, Lai-Har Chi, John Love, Frank D. Stephen, Thomas R. Sutter, Kevin G. Osteen, Theodore G. Costich, Ronald E. Batt, Stephen T. Koury, and James R. Olson

Effect of TCDD Exposure on CYP1A1 and CYP1B1 Expression in Explant Cultures of Human Endometrium
Toxicol. Sci. 2001 62: 299-314; doi:10.1093/toxsci/62.2.299 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Patrick J. Devine, I. Glenn Sipes, and Patricia B. Hoyer

Effect of 4-Vinylcyclohexene Diepoxide Dosing in Rats on GSH Levels in Liver and Ovaries
Toxicol. Sci. 2001 62: 315-320; doi:10.1093/toxsci/62.2.315 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Martin J. J. Ronis, James Aronson, Guan Gen Gao, William Hogue, Robert A. Skinner, Thomas M. Badger, and Charles K. Lumpkin, Jr.

Skeletal Effects of Developmental Lead Exposure in Rats
Toxicol. Sci. 2001 62: 321-329; doi:10.1093/toxsci/62.2.321 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

RISK ASSESSMENT:

Edward J. Calabrese and Linda A. Baldwin

The Frequency of U-Shaped Dose Responses in the Toxicological Literature
Toxicol. Sci. 2001 62: 330-338; doi:10.1093/toxsci/62.2.330 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

SAFETY EVALUATION:

V. C. Moser, S. Barone, Jr., R. J. Smialowicz, M. W. Harris, B. J. Davis, D. Overstreet, M. Mauney, and R. E. Chapin

The Effects of Perinatal Tebuconazole Exposure on Adult Neurological, Immunological, and Reproductive Function in Rats
Toxicol. Sci. 2001 62: 339-352; doi:10.1093/toxsci/62.2.339 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

SYSTEMS TOXICOLOGY:

David C. McMillan, Laura J. C. Bolchoz, and David J. Jollow

Favism: Effect of Divicine on Rat Erythrocyte Sulfhydryl Status, Hexose Monophosphate Shunt Activity, Morphology, and Membrane Skeletal Proteins
Toxicol. Sci. 2001 62: 353-359; doi:10.1093/toxsci/62.2.353 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

LETTERS TO THE EDITOR:

Frederick W. Oehme

Letter
Toxicol. Sci. 2001 62: 360; doi:10.1093/toxsci/62.2.360 [Extract] [FREE Full Text] [PDF] [Request Permissions]  

Gabriel L. Plaa

Reply
Toxicol. Sci. 2001 62: 360; doi:10.1093/toxsci/62.2.360-a [Extract] [FREE Full Text] [PDF] [Request Permissions]  

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