Toxicological Sciences

PROFILES IN TOXICOLOGY:

Paul E. Morrow, Margaret C. Bruce, and John Doull

Louis James Casarett (1927–1972)
Toxicol. Sci. 2001 63: 151-152; doi:10.1093/toxsci/63.2.151 [Extract] [FREE Full Text] [PDF] [Request Permissions]  

FORUM:

Ernest Hodgson

Genetically Modified Plants and Human Health Risks: Can Additional Research Reduce Uncertainties and Increase Public Confidence?
Toxicol. Sci. 2001 63: 153-156; doi:10.1093/toxsci/63.2.153 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

BIOTRANSFORMATION AND TOXICOKINETICS:

David J. Burchfield, Ian R. Tebbett, and Kevin J. Anderson

Elimination of Cocaine by Pregnant Sheep following Single or Multiple Exposures
Toxicol. Sci. 2001 63: 157-159; doi:10.1093/toxsci/63.2.157 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Harvey J. Clewell, III, P. Robinan Gentry, Jeffery M. Gearhart, Tammie R. Covington, Marcy I. Banton, and Melvin E. Andersen

Development of a Physiologically Based Pharmacokinetic Model of Isopropanol and Its Metabolite Acetone
Toxicol. Sci. 2001 63: 160-172; doi:10.1093/toxsci/63.2.160 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

ENDOCRINE TOXICOLOGY:

Andriana D. Papaconstantinou, Benjamin R. Fisher, Thomas H. Umbreit, Peter L. Goering, Nicholas T. Lappas, and Ken M. Brown

Effects of ß-Estradiol and Bisphenol A on Heat Shock Protein Levels and Localization in the Mouse Uterus Are Antagonized by the Antiestrogen ICI 182,780
Toxicol. Sci. 2001 63: 173-180; doi:10.1093/toxsci/63.2.173 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Surekha Shridhar, Anne Farley, Robert L. Reid, Warren G. Foster, and Dean A. Van Vugt

The Effect of 2,3,7,8-Tetrachlorodibenzo-p-dioxin on Corticotrophin-Releasing Hormone, Arginine Vasopressin, and Pro-opiomelanocortin mRNA Levels in the Hypothalamus of the Cynomolgus Monkey
Toxicol. Sci. 2001 63: 181-188; doi:10.1093/toxsci/63.2.181 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

MOLECULAR AND GENETIC TOXICOLOGY:

Wei Qu, Kazimierz S. Kasprzak, Maria Kadiiska, Jie Liu, Hua Chen, Anna Maciag, Ronald P. Mason, and Michael P. Waalkes

Mechanisms of Arsenic-Induced Cross-Tolerance to Nickel Cytotoxicity, Genotoxicity, and Apoptosis in Rat Liver Epithelial Cells
Toxicol. Sci. 2001 63: 189-195; doi:10.1093/toxsci/63.2.189 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Qihong Huang, Robert T. Dunn, II, Supriya Jayadev, Olimpia DiSorbo, Franklin D. Pack, Spencer B. Farr, Raymond E. Stoll, and Kerry T. Blanchard

Assessment of Cisplatin-Induced Nephrotoxicity by Microarray Technology
Toxicol. Sci. 2001 63: 196-207; doi:10.1093/toxsci/63.2.196 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

NEUROTOXICOLOGY:

Clint Rosenfeld, Ahmed Kousba, and Lester G. Sultatos

Interactions of Rat Brain Acetylcholinesterase with the Detergent Triton X-100 and the Organophosphate Paraoxon
Toxicol. Sci. 2001 63: 208-213; doi:10.1093/toxsci/63.2.208 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

RESPIRATORY TOXICOLOGY:

Christopher E. Helt, Raymond C. Rancourt, Rhonda J. Staversky, and Michael A. O'Reilly

p53-Dependent Induction of p21^{Cip1/WAF1/Sdi1} Protects against Oxygen-Induced Toxicity
Toxicol. Sci. 2001 63: 214-222; doi:10.1093/toxsci/63.2.214 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

RISK ASSESSMENT:

Jamal El Yazal, Shashidhar N. Rao, Adrea Mehl, and William Slikker, Jr.

Prediction of Organophosphorus Acetylcholinesterase Inhibition Using Three-Dimensional Quantitative Structure-Activity Relationship (3D-QSAR) Methods
Toxicol. Sci. 2001 63: 223-232; doi:10.1093/toxsci/63.2.223 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

SAFETY EVALUATION:

J. Enrique Cometto-Muñiz, William S. Cain, Michael H. Abraham, and Joelle M. R. Gola

Ocular and Nasal Trigeminal Detection of Butyl Acetate and Toluene Presented Singly and in Mixtures
Toxicol. Sci. 2001 63: 233-244; doi:10.1093/toxsci/63.2.233 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Ghanta N. Rao, Richard W. Morris, and John C. Seely

Beneficial Effects of NTP-2000 Diet on Growth, Survival, and Kidney and Heart Diseases of Fischer 344 Rats in Chronic Studies
Toxicol. Sci. 2001 63: 245-255; doi:10.1093/toxsci/63.2.245 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

SYSTEMS TOXICOLOGY:

E. O'Brien, A. H. Heussner, and Daniel R. Dietrich

Species-, Sex-, and Cell Type-Specific Effects of Ochratoxin A and B
Toxicol. Sci. 2001 63: 256-264; doi:10.1093/toxsci/63.2.256 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

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