Toxicological Sciences

TOXICOLOGICAL HIGHLIGHT:

John F. Gierthy

Testing for Endocrine Disruption: How Much is Enough?
Toxicol. Sci. 2002 68: 1-3; doi:10.1093/toxsci/68.1.1 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

FORUM:

Ian Kimber and Rebecca J. Dearman

Approaches to Assessment of the Allergenic Potential of Novel Proteins in Food from Genetically Modified Crops
Toxicol. Sci. 2002 68: 4-8; doi:10.1093/toxsci/68.1.4 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Kathleen A. Haberny, Merle G. Paule, Andrew C. Scallet, Frank D. Sistare, David S. Lester, Joseph P. Hanig, and William Slikker, Jr.

Ontogeny of the N-Methyl-D-Aspartate (NMDA) Receptor System and Susceptibility to Neurotoxicity
Toxicol. Sci. 2002 68: 9-17; doi:10.1093/toxsci/68.1.9 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

BIOTRANSFORMATION AND TOXICOKINETICS:

Rhonda M. Brand and Cynthia Mueller

Transdermal Penetration of Atrazine, Alachlor, and Trifluralin: Effect of Formulation
Toxicol. Sci. 2002 68: 18-23; doi:10.1093/toxsci/68.1.18 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Ellen A. Cannady, Cheryl A. Dyer, Patricia J. Christian, I. Glenn Sipes, and Patricia B. Hoyer

Expression and Activity of Microsomal Epoxide Hydrolase in Follicles Isolated from Mouse Ovaries
Toxicol. Sci. 2002 68: 24-31; doi:10.1093/toxsci/68.1.24 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Hideo Kurebayashi, Ryoko Harada, Richard K. Stewart, Hiroaki Numata, and Yasuo Ohno

Disposition of a Low Dose of Bisphenol A in Male and Female Cynomolgus Monkeys
Toxicol. Sci. 2002 68: 32-42; doi:10.1093/toxsci/68.1.32 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

CARCINOGENICITY:

Joungjoa Park, Lisa M. Kamendulis, and James E. Klaunig

Mechanisms of 2-Butoxyethanol Carcinogenicity: Studies on Syrian Hamster Embryo (SHE) Cell Transformation
Toxicol. Sci. 2002 68: 43-50; doi:10.1093/toxsci/68.1.43 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Rebecca E. Watson and Jay I. Goodman

Effects of Phenobarbital on DNA Methylation in GC-Rich Regions of Hepatic DNA from Mice That Exhibit Different Levels of Susceptibility to Liver Tumorigenesis
Toxicol. Sci. 2002 68: 51-58; doi:10.1093/toxsci/68.1.51 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Burhan I. Ghanayem, Abraham Nyska, Joseph K. Haseman, and John R. Bucher

Acrylonitrile Is a Multisite Carcinogen in Male and Female B6C3F1 Mice
Toxicol. Sci. 2002 68: 59-68; doi:10.1093/toxsci/68.1.59 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

ENVIRONMENTAL TOXICOLOGY:

Joel N. Meyer, Diane E. Nacci, and Richard T. Di Giulio

Cytochrome P4501A (CYP1A) in Killifish (Fundulus heteroclitus): Heritability of Altered Expression and Relationship to Survival in Contaminated Sediments
Toxicol. Sci. 2002 68: 69-81; doi:10.1093/toxsci/68.1.69 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

IMMUNOTOXICOLOGY:

Donna E. Muscarella and Stephen E. Bloom

Differential Activation of the c-Jun N-Terminal Kinase Pathway in Arsenite-Induced Apoptosis and Sensitization of Chemically Resistant Compared to Susceptible B-Lymphoma Cell Lines
Toxicol. Sci. 2002 68: 82-92; doi:10.1093/toxsci/68.1.82 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

MOLECULAR AND GENETIC TOXICOLOGY:

Christine L. Merrill, Hong Ni, Lawrence W. Yoon, Mark A. Tirmenstein, Padma Narayanan, Gina R. Benavides, M. J. Easton, Donald R. Creech, Catherine X. Hu, David C. McFarland, Laura M. Hahn, Heath C. Thomas, and Kevin T. Morgan

Etomoxir-Induced Oxidative Stress in HepG2 Cells Detected by Differential Gene Expression Is Confirmed Biochemically
Toxicol. Sci. 2002 68: 93-101; doi:10.1093/toxsci/68.1.93 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Sheryl R. Krig, Roshantha A. S. Chandraratna, Mary M. J. Chang, Reen Wu, and Robert H. Rice

Gene-Specific TCDD Suppression of RAR- and RXR-Mediated Induction of Tissue Transglutaminase
Toxicol. Sci. 2002 68: 102-108; doi:10.1093/toxsci/68.1.102 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

NEUROTOXICOLOGY:

Philip J. Bushnell, Virginia C. Moser, Robert C. MacPhail, Wendy M. Oshiro, Ethel C. Derr-Yellin, Pamela M. Phillips, and Prasada Rao S. Kodavanti

Neurobehavioral Assessments of Rats Perinatally Exposed to a Commercial Mixture of Polychlorinated Biphenyls
Toxicol. Sci. 2002 68: 109-120; doi:10.1093/toxsci/68.1.109 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

REPRODUCTIVE AND DEVELOPMENTAL TOXICOLOGY:

R. W. Tyl, C. B. Myers, M. C. Marr, B. F. Thomas, A. R. Keimowitz, D. R. Brine, M. M. Veselica, P. A. Fail, T. Y. Chang, J. C. Seely, R. L. Joiner, J. H. Butala, S. S. Dimond, S. Z. Cagen, R. N. Shiotsuka, G. D. Stropp, and J. M. Waechter

Three-Generation Reproductive Toxicity Study of Dietary Bisphenol A in CD Sprague-Dawley Rats
Toxicol. Sci. 2002 68: 121-146; doi:10.1093/toxsci/68.1.121 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

J. Odum, P. A. Lefevre, H. Tinwell, J. P. Van Miller, R. L. Joiner, R. E. Chapin, N. T. Wallis, and J. Ashby

Comparison of the Developmental and Reproductive Toxicity of Diethylstilbestrol Administered to Rats in Utero, Lactationally, Preweaning, or Postweaning
Toxicol. Sci. 2002 68: 147-163; doi:10.1093/toxsci/68.1.147 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Gary R. Klinefelter, Lillian F. Strader, Juan D. Suarez, and Naomi L. Roberts

Bromochloroacetic Acid Exerts Qualitative Effects on Rat Sperm: Implications for a Novel Biomarker
Toxicol. Sci. 2002 68: 164-173; doi:10.1093/toxsci/68.1.164 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Katie J. Turner, Norman J. Barlow, Melanie F. Struve, Duncan G. Wallace, Kevin W. Gaido, David C. Dorman, and Paul M. D. Foster

Effects of in Utero Exposure to the Organophosphate Insecticide Fenitrothion on Androgen-Dependent Reproductive Development in the Crl:CD(SD)BR Rat
Toxicol. Sci. 2002 68: 174-183; doi:10.1093/toxsci/68.1.174 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Jorge M. Naciff, M. Lynn Jump, Suzanne M. Torontali, Gregory J. Carr, Jay P. Tiesman, Gary J. Overmann, and George P. Daston

Gene Expression Profile Induced by 17-Ethynyl Estradiol, Bisphenol A, and Genistein in the Developing Female Reproductive System of the Rat
Toxicol. Sci. 2002 68: 184-199; doi:10.1093/toxsci/68.1.184 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

D. J. Oakes, W. S. Webster, P. D. C. Brown-Woodman, and H. E. Ritchie

A Study of the Potential for a Herbicide Formulation Containing 2,4-D and Picloram to Cause Male-Mediated Developmental Toxicity in Rats
Toxicol. Sci. 2002 68: 200-206; doi:10.1093/toxsci/68.1.200 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Suzanne R. Thornton, Raymond E. Schroeder, Rodney L. Robison, Dean E. Rodwell, David A. Penney, Kenneth D. Nitschke, and Wendy K. Sherman

Embryo-Fetal Developmental and Reproductive Toxicology of Vinyl Chloride in Rats
Toxicol. Sci. 2002 68: 207-219; doi:10.1093/toxsci/68.1.207 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

RISK ASSESSMENT:

James P. Luyendyk, Kate C. Shores, Patricia E. Ganey, and Robert A. Roth

Bacterial Lipopolysaccharide Exposure Alters Aflatoxin B₁ Hepatotoxicity: Benchmark Dose Analysis for Markers of Liver Injury
Toxicol. Sci. 2002 68: 220-225; doi:10.1093/toxsci/68.1.220 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

SAFETY EVALUATION:

J. R. Herman, L. A. Dethloff, E. J. McGuire, R. F. Parker, K. M. Walsh, A. W. Gough, H. Masuda, and F. A. de la Iglesia

Rodent Carcinogenicity with the Thiazolidinedione Antidiabetic Agent Troglitazone
Toxicol. Sci. 2002 68: 226-236; doi:10.1093/toxsci/68.1.226 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Goar Melkonian, Lucia Cheung, Rebecca Marr, Cathy Tong, and P. Talbot

Mainstream and Sidestream Cigarette Smoke Inhibit Growth and Angiogenesis in the Day 5 Chick Chorioallantoic Membrane
Toxicol. Sci. 2002 68: 237-248; doi:10.1093/toxsci/68.1.237 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Andrew M. Seacat, Peter J. Thomford, Kris J. Hansen, Geary W. Olsen, Marvin T. Case, and John L. Butenhoff

Subchronic Toxicity Studies on Perfluorooctanesulfonate Potassium Salt in Cynomolgus Monkeys
Toxicol. Sci. 2002 68: 249-264; doi:10.1093/toxsci/68.1.249 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

To see an article, click its [Full Text] or [PDF] link. To review many abstracts, check the boxes to the left of the titles you want, and click the 'Get All Checked Abstract(s)' button. To see one abstract at a time, click its [Abstract] link.