Toxicological Sciences

EDITORIAL:

Lois Lehman-McKeeman

EDITORIAL
Toxicol. Sci. 2003 71: 1; doi:10.1093/toxsci/71.1.1 [Extract] [FREE Full Text] [PDF] [Request Permissions]  

SOCIETY OF TOXICOLOGY POSITION PAPER:

The Safety of Genetically Modified Foods Produced through Biotechnology
Toxicol. Sci. 2003 71: 2-8; doi:10.1093/toxsci/71.1.2 [Extract] [FREE Full Text] [PDF] [Request Permissions]  

TOXICOLOGICAL HIGHLIGHT:

Mahin D. Maines

Bile Pigments: Newcomers to the Cell Signaling Arena
Toxicol. Sci. 2003 71: 9-10; doi:10.1093/toxsci/71.1.9 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

BIOTRANSFORMATION AND TOXICOKINETICS:

Thomas K. H. Chang, Jie Chen, Vincent Pillay, Jeong-Yau Ho, and Stelvio M. Bandiera

Real-Time Polymerase Chain Reaction Analysis of CYP1B1 Gene Expression in Human Liver
Toxicol. Sci. 2003 71: 11-19; doi:10.1093/toxsci/71.1.11 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Pinpin Lin, Suh-Woan Hu, and Tzu-Hua Chang

Correlation between Gene Expression of Aryl Hydrocarbon Receptor (AhR), Hydrocarbon Receptor Nuclear Translocator (Arnt), Cytochromes P4501A1 (CYP1A1) and 1B1 (CYP1B1), and Inducibility of CYP1A1 and CYP1B1 in Human Lymphocytes
Toxicol. Sci. 2003 71: 20-26; doi:10.1093/toxsci/71.1.20 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Lisa M. Sweeney, Michael L. Gargas, Dale E. Strother, and Gregory L. Kedderis

Physiologically Based Pharmacokinetic Model Parameter Estimation and Sensitivity and Variability Analyses for Acrylonitrile Disposition in Humans
Toxicol. Sci. 2003 71: 27-40; doi:10.1093/toxsci/71.1.27 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Ramesh Sarangapani, Justin Teeguarden, Melvin E. Andersen, Richard H. Reitz, and Kathleen P. Plotzke

Route-Specific Differences in Distribution Characteristics of Octamethylcyclotetrasiloxane in Rats: Analysis Using PBPK Models
Toxicol. Sci. 2003 71: 41-52; doi:10.1093/toxsci/71.1.41 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

CARCINOGENICITY:

William T. Stott, Keith A. Johnson, Rainer Bahnemann, Susan J. Day, and Randal J. McGuirk

Evaluation of Potential Modes of Action of Inhaled Ethylbenzene in Rats and Mice
Toxicol. Sci. 2003 71: 53-66; doi:10.1093/toxsci/71.1.53 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

ENVIRONMENTAL TOXICOLOGY:

Jyotsna Pangrekar, Panna L. Kole, Sangeet A. Honey, Subodh Kumar, and Harish C. Sikka

Metabolism of Chrysene by Brown Bullhead Liver Microsomes
Toxicol. Sci. 2003 71: 67-73; doi:10.1093/toxsci/71.1.67 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

REPRODUCTIVE AND DEVELOPMENTAL TOXICOLOGY:

Richard W. Lewis, Nigel Brooks, Gillian M. Milburn, Anthony Soames, Susan Stone, Michael Hall, and John Ashby

The Effects of the Phytoestrogen Genistein on the Postnatal Development of the Rat
Toxicol. Sci. 2003 71: 74-83; doi:10.1093/toxsci/71.1.74 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Barbara D. Abbott, Angela R. Buckalew, Michael J. DeVito, David Ross, P. Lamont Bryant, and Judith E. Schmid

EGF and TGF- Expression Influence the Developmental Toxicity of TCDD: Dose Response and AhR Phenotype in EGF, TGF-, and EGF + TGF- Knockout Mice
Toxicol. Sci. 2003 71: 84-95; doi:10.1093/toxsci/71.1.84 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Tetsuya Yamada, Gaku Ichihara, Hailan Wang, Xiaozhong Yu, Kei-ichiro Maeda, Hiroko Tsukamura, Michihiro Kamijima, Tamie Nakajima, and Yasuhiro Takeuchi

Exposure to 1-Bromopropane Causes Ovarian Dysfunction in Rats
Toxicol. Sci. 2003 71: 96-103; doi:10.1093/toxsci/71.1.96 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

RESPIRATORY TOXICOLOGY:

Bahman Asgharian, James T. Kelly, and Earl W. Tewksbury

Respiratory Deposition and Inhalability of Monodisperse Aerosols in Long-Evans Rats
Toxicol. Sci. 2003 71: 104-111; doi:10.1093/toxsci/71.1.104 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

SYSTEMS TOXICOLOGY:

Marjo Niittynen, Jouni T. Tuomisto, Seppo Auriola, Raimo Pohjanvirta, Paula Syrjälä, Ulla Simanainen, Matti Viluksela, and Jouko Tuomisto

2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD)-Induced Accumulation of Biliverdin and Hepatic Peliosis in Rats
Toxicol. Sci. 2003 71: 112-123; doi:10.1093/toxsci/71.1.112 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Steven B. Yee, Patricia E. Ganey, and Robert A. Roth

The Role of Kupffer Cells and TNF- in Monocrotaline and Bacterial Lipopolysaccharide-Induced Liver Injury
Toxicol. Sci. 2003 71: 124-132; doi:10.1093/toxsci/71.1.124 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

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