Toxicological Sciences

EDITORIAL:

Lois Lehman-McKeeman

Impact and Other Factors: What’s in a Number?
Toxicol. Sci. 2003 71: 133; doi:10.1093/toxsci/71.2.133 [Extract] [FREE Full Text] [PDF] [Request Permissions]  

TOXICOLOGICAL HIGHLIGHT:

Joseph V. Rodricks

Hormesis and Toxicological Risk Assessment
Toxicol. Sci. 2003 71: 134-136; doi:10.1093/toxsci/71.2.134 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

FORUM:

Rebecca J. Dearman, Catherine J. Betts, Neil Humphreys, Brian F. Flanagan, Nicola J. Gilmour, David A. Basketter, and Ian Kimber

Chemical Allergy: Considerations for the Practical Application of Cytokine Profiling
Toxicol. Sci. 2003 71: 137-145; doi:10.1093/toxsci/71.2.137 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

J. Kevin Chipman, Angela Mally, and Gareth O. Edwards

Disruption of Gap Junctions in Toxicity and Carcinogenicity
Toxicol. Sci. 2003 71: 146-153; doi:10.1093/toxsci/71.2.146 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

BIOTRANSFORMATION AND TOXICOKINETICS:

Emmanuel E. Brako, Allison K. Wilson, Margaret M. Jonah, Carmen A. Blum, Elizabeth A. Cerny, Kanesha L. Williams, and Maryka H. Bhattacharyya

Cadmium Pathways during Gestation and Lactation in Control versus Metallothoinein 1,2-Knockout Mice
Toxicol. Sci. 2003 71: 154-163; doi:10.1093/toxsci/71.2.154 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Timothy R. Fennell, Rodney W. Snyder, Wojciech L. Krol, and Susan C. J. Sumner

Comparison of the Hemoglobin Adducts Formed by Administration of N-Methylolacrylamide and Acrylamide to Rats
Toxicol. Sci. 2003 71: 164-175; doi:10.1093/toxsci/71.2.164 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Torka S. Poet, Jolen J. Soelberg, Karl K. Weitz, Terryl J. Mast, Rodney A. Miller, Brian D. Thrall, and Richard A. Corley

Mode of Action and Pharmacokinetic Studies of 2-Butoxyethanol in the Mouse with an Emphasis on Forestomach Dosimetry
Toxicol. Sci. 2003 71: 176-189; doi:10.1093/toxsci/71.2.176 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

CARCINOGENICITY:

Kristy A. Warner, Martha J. Fernstrom, and Randall J. Ruch

Inhibition of Mouse Hepatocyte Gap Junctional Intercellular Communication by Phenobarbital Correlates with Strain-Specific Hepatocarcinogenesis
Toxicol. Sci. 2003 71: 190-197; doi:10.1093/toxsci/71.2.190 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

N. B. Ress, J. R. Hailey, R. R. Maronpot, J. R. Bucher, G. S. Travlos, J. K. Haseman, D. P. Orzech, J. D. Johnson, and M. R. Hejtmancik

Toxicology and Carcinogenesis Studies of Microencapsulated Citral in Rats and Mice
Toxicol. Sci. 2003 71: 198-206; doi:10.1093/toxsci/71.2.198 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

IMMUNOTOXICOLOGY:

H.-M. Yang, L. Butterworth, A. E. Munson, and B. Jean Meade

Respiratory Exposure to Diesel Exhaust Particles Decreases the Spleen IgM Response to a T Cell-Dependent Antigen in Female B6C3F1 Mice
Toxicol. Sci. 2003 71: 207-216; doi:10.1093/toxsci/71.2.207 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

REPRODUCTIVE AND DEVELOPMENTAL TOXICOLOGY:

E. W. Carney, L. H. Pottenger, K. A. Johnson, A. B. Liberacki, B. Tornesi, M. D. Dryzga, S. C. Hansen, and W. J. Breslin

Significance of 2-Methoxypropionic Acid Formed from ß-Propylene Glycol Monomethyl Ether: Integration of Pharmacokinetic and Developmental Toxicity Assessments in Rabbits
Toxicol. Sci. 2003 71: 217-228; doi:10.1093/toxsci/71.2.217 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

RESPIRATORY TOXICOLOGY:

William K. Nichols, Rashmi Mehta, Konstantine Skordos, Katherine Macé, Andrea M. A. Pfeifer, Brian A. Carr, Tamara Minko, Scott W. Burchiel, and Garold S. Yost

3-Methylindole-Induced Toxicity to Human Bronchial Epithelial Cell Lines
Toxicol. Sci. 2003 71: 229-236; doi:10.1093/toxsci/71.2.229 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Urmila P. Kodavanti, Carolyn F. Moyer, Allen D. Ledbetter, Mette C. Schladweiler, Daniel L. Costa, Russ Hauser, David C. Christiani, and Abraham Nyska

Inhaled Environmental Combustion Particles Cause Myocardial Injury in the Wistar Kyoto Rat
Toxicol. Sci. 2003 71: 237-245; doi:10.1093/toxsci/71.2.237 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

RISK ASSESSMENT:

Edward J. Calabrese and Linda A. Baldwin

The Hormetic Dose-Response Model Is More Common than the Threshold Model in Toxicology
Toxicol. Sci. 2003 71: 246-250; doi:10.1093/toxsci/71.2.246 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

SAFETY EVALUATION:

Christine Nellemann, Majken Dalgaard, Henrik Rye Lam, and Anne Marie Vinggaard

The Combined Effects of Vinclozolin and Procymidone Do Not Deviate from Expected Additivity in Vitro and in Vivo
Toxicol. Sci. 2003 71: 251-262; doi:10.1093/toxsci/71.2.251 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Kjersti Horais, Victor Hruby, Steven Rossi, Dasa Cizkova, Carol Meschter, Robert Dorr, and Tony L. Yaksh

Effects of Chronic Intrathecal Infusion of a Opioid Agonist in Dogs
Toxicol. Sci. 2003 71: 263-275; doi:10.1093/toxsci/71.2.263 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

SYSTEMS TOXICOLOGY:

Irene D. Román, M. Dolores Fernández-Moreno, Jesús A. Fueyo, Marcelo G. Roma, and Roger Coleman

Cyclosporin A Induced Internalization of the Bile Salt Export Pump in Isolated Rat Hepatocyte Couplets
Toxicol. Sci. 2003 71: 276-281; doi:10.1093/toxsci/71.2.276 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

LETTERS TO THE EDITOR:

Vsevolod E. Kostrubsky, Ramin Rahbari, Alberto Lodola, and Thomas Davies

Letter
Toxicol. Sci. 2003 71: 282; doi:10.1093/toxsci/71.2.282 [Extract] [FREE Full Text] [PDF] [Request Permissions]  

Mark Tirmenstein, Catherine Hu, Tracy Gales, Beverly Maleeff, Padma Narayanan, Edit Kurali, Timothy Hart, Heath Thomas, and Lester Schwartz

Reply
Toxicol. Sci. 2003 71: 282-284; doi:10.1093/toxsci/71.2.282-a [Extract] [FREE Full Text] [PDF] [Request Permissions]  

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