Toxicological Sciences

EDITORIAL:

Lois Lehman-McKeeman and Richard E. Peterson

Guidelines Governing Conflict of Interest
Toxicol. Sci. 2003 72: 183-184; doi:10.1093/toxsci/kfg051 [Extract] [FREE Full Text] [PDF] [Request Permissions]  

TOXICOLOGICAL HIGHLIGHT:

E. Jon Popke

From Anticholinesterase Toxicity to Alzheimer’s Disease: Important Interactions of Cholinergic and NMDA Receptor Systems
Toxicol. Sci. 2003 72: 185-187; doi:10.1093/toxsci/kfg050 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

PROFILES IN TOXICOLOGY:

Roger O. McClellan

The Legacy of Leon Golberg (1915–1987)
ToxSci Advance Access published on March 7, 2003
Toxicol. Sci. 2003 72: 188-192; doi:10.1093/toxsci/kfg041 [Extract] [FREE Full Text] [PDF] [Request Permissions]  

BIOTRANSFORMATION AND TOXICOKINETICS:

T. S. Poet, H. Wu, A. A. Kousba, and C. Timchalk

In Vitro Rat Hepatic and Intestinal Metabolism of the Organophosphate Pesticides Chlorpyrifos and Diazinon
ToxSci Advance Access published on March 7, 2003
Toxicol. Sci. 2003 72: 193-200; doi:10.1093/toxsci/kfg035 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

CARCINOGENICITY:

Alison K. Bauer, Brenda Faiola, Diane J. Abernethy, Rosemarie Marchan, Linda J. Pluta, Victoria A. Wong, Frank J. Gonzalez, Byron E. Butterworth, Susan J. Borghoff, Jeffrey I. Everitt, and Leslie Recio

Male Mice Deficient in Microsomal Epoxide Hydrolase Are Not Susceptible to Benzene-Induced Toxicity
ToxSci Advance Access published on March 7, 2003
Toxicol. Sci. 2003 72: 201-209; doi:10.1093/toxsci/kfg024 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Jeffrey A. Dill, Alfred F. Fuciarelli, Kyeonghee M. Lee, Kathleen M. Mellinger, Po C. Chan, Leo T. Burka, and Joseph H. Roycroft

Single Administration Toxicokinetic Studies of Decalin (Decahydronaphthalene) in Rats and Mice
Toxicol. Sci. 2003 72: 210-222; doi:10.1093/toxsci/kfg027 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Jeffrey A. Dill, Kyeonghee M. Lee, Roger A. Renne, Rodney A. Miller, Alfred F. Fuciarelli, Kathy M. Gideon, Po C. Chan, Leo T. Burka, and Joseph H. Roycroft

_2u-Globulin Nephropathy and Carcinogenicity following Exposure to Decalin (Decahydronaphthalene) in F344/N Rats
Toxicol. Sci. 2003 72: 223-234; doi:10.1093/toxsci/kfg028 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

ENDOCRINE TOXICOLOGY:

Yoshihisa Kato, Koichi Haraguchi, Tomoaki Yamazaki, Yuriko Ito, Shoji Miyajima, Kiyomitsu Nemoto, Nobuyuki Koga, Ryohei Kimura, and Masakuni Degawa

Effects of Polychlorinated Biphenyls, Kanechlor-500, on Serum Thyroid Hormone Levels in Rats and Mice
Toxicol. Sci. 2003 72: 235-241; doi:10.1093/toxsci/kfg025 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

ENVIRONMENTAL TOXICOLOGY:

Adedayo Adeeko, Daming Li, Josée Doucet, Gerard M. Cooke, Jacquetta M. Trasler, Bernard Robaire, and Barbara F. Hales

Gestational Exposure to Persistent Organic Pollutants: Maternal Liver Residues, Pregnancy Outcome, and Effects on Hepatic Gene Expression Profiles in the Dam and Fetus
ToxSci Advance Access published on March 7, 2003
Toxicol. Sci. 2003 72: 242-252; doi:10.1093/toxsci/kfg023 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Yuki Tsuchiya, Miki Nakajima, Satsuki Itoh, Masashi Iwanari, and Tsuyoshi Yokoi

Expression of Aryl Hydrocarbon Receptor Repressor in Normal Human Tissues and Inducibility by Polycyclic Aromatic Hydrocarbons in Human Tumor-Derived Cell Lines
ToxSci Advance Access published on March 7, 2003
Toxicol. Sci. 2003 72: 253-259; doi:10.1093/toxsci/kfg022 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Nancy W. Shappell, Uli Carlino-MacDonald, Shantu Amin, Subodh Kumar, and Harish C. Sikka

Comparative Metabolism of Chrysene and 5-Methylchrysene by Rat and Rainbow Trout Liver Microsomes
ToxSci Advance Access published on March 7, 2003
Toxicol. Sci. 2003 72: 260-266; doi:10.1093/toxsci/kfg039 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Rosane Maria Salvi, Diogo R. Lara, Eduardo S. Ghisolfi, Luis V. Portela, Renato D. Dias, and Diogo O. Souza

Neuropsychiatric Evaluation in Subjects Chronically Exposed to Organophosphate Pesticides
Toxicol. Sci. 2003 72: 267-271; doi:10.1093/toxsci/kfg034 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

MOLECULAR AND GENETIC TOXICOLOGY:

Udayan M. Apte, Pallavi B. Limaye, D. Desaiah, Thomas J. Bucci, Alan Warbritton, and Harihara M. Mehendale

Mechanisms of Increased Liver Tissue Repair and Survival in Diet-Restricted Rats Treated with Equitoxic Doses of Thioacetamide
ToxSci Advance Access published on March 7, 2003
Toxicol. Sci. 2003 72: 272-282; doi:10.1093/toxsci/kfg021 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Ssu-Ching Chen, Chih-Ming Kao, Mei-Han Huang, Ming-Kuei Shih, Ya-Lei Chen, Shiao-Ping Huang, and Tsan-Zon Liu

Assessment of Genotoxicity of Benzidine and Its Structural Analogues to Human Lymphocytes Using Comet Assay
Toxicol. Sci. 2003 72: 283-288; doi:10.1093/toxsci/kfg026 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

NEUROTOXICOLOGY:

Andrzej Dekundy, Rafal M. Kaminski, and Waldemar A. Turski

Dizocilpine Improves Beneficial Effects of Cholinergic Antagonists in Anticholinesterase-Treated Mice
Toxicol. Sci. 2003 72: 289-295; doi:10.1093/toxsci/kfg013 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Andrew C. Scallet, Marcia Wofford, John C. Meredith, William T. Allaben, and Sherry A. Ferguson

Dietary Exposure to Genistein Increases Vasopressin but Does Not Alter ß-Endorphin in the Rat Hypothalamus
Toxicol. Sci. 2003 72: 296-300; doi:10.1093/toxsci/kfg029 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

REPRODUCTIVE AND DEVELOPMENTAL TOXICOLOGY:

Ty T. Higuchi, Jennifer S. Palmer, L. Earl Gray, Jr., and D. N. Rao Veeramachaneni

Effects of Dibutyl Phthalate in Male Rabbits following in Utero, Adolescent, or Postpubertal Exposure
ToxSci Advance Access published on March 7, 2003
Toxicol. Sci. 2003 72: 301-313; doi:10.1093/toxsci/kfg036 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Jorge M. Naciff, Gary J. Overmann, Suzanne M. Torontali, Gregory J. Carr, Jay P. Tiesman, Brian D. Richardson, and George P. Daston

Gene Expression Profile Induced by 17-Ethynyl Estradiol in the Prepubertal Female Reproductive System of the Rat
ToxSci Advance Access published on March 7, 2003
Toxicol. Sci. 2003 72: 314-330; doi:10.1093/toxsci/kfg037 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

RESPIRATORY TOXICOLOGY:

Amy L. Lambert, Frances S. Trasti, James B. Mangum, and Jeffrey I. Everitt

Effect of Preexposure to Ultrafine Carbon Black on Respiratory Syncytial Virus Infection in Mice
Toxicol. Sci. 2003 72: 331-338; doi:10.1093/toxsci/kfg031 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Amy L. Lambert, James B. Mangum, Michael P. DeLorme, and Jeffrey I. Everitt

Ultrafine Carbon Black Particles Enhance Respiratory Syncytial Virus-Induced Airway Reactivity, Pulmonary Inflammation, and Chemokine Expression
ToxSci Advance Access published on March 7, 2003
Toxicol. Sci. 2003 72: 339-346; doi:10.1093/toxsci/kfg032 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

SAFETY EVALUATION:

D. W. Lynch, M. E. Placke, R. L. Persing, and M. J. Ryan

Thirteen-Week Inhalation Toxicity of N,N-Dimethylformamide in F344/N Rats and B6C3F1 Mice
ToxSci Advance Access published on March 7, 2003
Toxicol. Sci. 2003 72: 347-358; doi:10.1093/toxsci/kfg033 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Jorge I. González Borroto, Amadeu Creus, Ricard Marcos, Ricard Mollà, and Jorge Zapatero

The Mutagenic Potential of the Furylethylene Derivative 2-Furyl-1-nitroethene in the Mouse Bone Marrow Micronucleus Test
ToxSci Advance Access published on March 7, 2003
Toxicol. Sci. 2003 72: 359-362; doi:10.1093/toxsci/kfg038 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

G. Bhanuprakash Reddy, Arjun L. Khandare, P. Yadagiri Reddy, G. Shankar Rao, N. Balakrishna, and I. Srivalli

Antioxidant Defense System and Lipid Peroxidation in Patients with Skeletal Fluorosis and in Fluoride-Intoxicated Rabbits
Toxicol. Sci. 2003 72: 363-368; doi:10.1093/toxsci/kfg030 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

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