Toxicological Sciences

TOXICOLOGICAL HIGHLIGHT:

Anne C. Walsh

Regulation of Nrf2-Mediated Induction of Glutamate Cysteine Ligase Modulatory Gene (GCLM) Expression: Considerations for Future Studies
ToxSci Advance Access published on March 25, 2003
Toxicol. Sci. 2003 73: 1-3; doi:10.1093/toxsci/kfg085 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

PROFILES IN TOXICOLOGY:

Bernard D. Goldstein

Sidney Laskin (1919–1976)
ToxSci Advance Access published on March 25, 2003
Toxicol. Sci. 2003 73: 4-7; doi:10.1093/toxsci/kfg069 [Extract] [FREE Full Text] [PDF] [Request Permissions]  

FORUM:

Gregory S. Ladics, Michael P. Holsapple, James D. Astwood, Ian Kimber, Leon M. J. Knippels, Ricki M. Helm, and Wumin Dong

Workshop Overview: Approaches to the Assessment of the Allergenic Potential of Food from Genetically Modified Crops
ToxSci Advance Access published on April 15, 2003
Toxicol. Sci. 2003 73: 8-16; doi:10.1093/toxsci/kfg055 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

BIOTRANSFORMATION AND TOXICOKINETICS:

Hideo Kurebayashi, Hiroshi Betsui, and Yasuo Ohno

Disposition of a Low Dose of ¹⁴C-Bisphenol A in Male Rats and Its Main Biliary Excretion as BPA Glucuronide
ToxSci Advance Access published on April 15, 2003
Toxicol. Sci. 2003 73: 17-25; doi:10.1093/toxsci/kfg040 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Chin-Hsiang Tsai, Po-Hsiung Lin, Melissa A. Troester, and Stephen M. Rappaport

Formation and Removal of Pentachlorophenol-Derived Protein Adducts in Rodent Liver under Acute, Multiple, and Chronic Dosing Regimens
ToxSci Advance Access published on April 15, 2003
Toxicol. Sci. 2003 73: 26-35; doi:10.1093/toxsci/kfg057 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Lalitha V. Iyer, Mark N. Ho, Walter M. Shinn, Wallace W. Bradford, Mary J. Tanga, Shirley S. Nath, and Carol E. Green

Glucuronidation of 1'-Hydroxyestragole (1'-HE) by Human UDP-Glucuronosyltransferases UGT2B7 and UGT1A9
ToxSci Advance Access published on March 25, 2003
Toxicol. Sci. 2003 73: 36-43; doi:10.1093/toxsci/kfg066 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Ki-Wan Oh, Ting Qian, David A. Brenner, and John J. Lemasters

Salicylate Enhances Necrosis and Apoptosis Mediated by the Mitochondrial Permeability Transition
ToxSci Advance Access published on April 15, 2003
Toxicol. Sci. 2003 73: 44-52; doi:10.1093/toxsci/kfg045 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

ENVIRONMENTAL TOXICOLOGY:

Ronald L. Jenkins, Elizabeth M. Wilson, Robert A. Angus, W. Mike Howell, and Marion Kirk

Androstenedione and Progesterone in the Sediment of a River Receiving Paper Mill Effluent
ToxSci Advance Access published on April 15, 2003
Toxicol. Sci. 2003 73: 53-59; doi:10.1093/toxsci/kfg042 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Qiang Cheng, Nicholas Valmas, Paul E. B. Reilly, Patrick J. Collins, Rosemary Kopittke, and Paul R. Ebert

Caenorhabditis elegans Mutants Resistant to Phosphine Toxicity Show Increased Longevity and Cross-Resistance to the Synergistic Action of Oxygen
ToxSci Advance Access published on April 15, 2003
Toxicol. Sci. 2003 73: 60-65; doi:10.1093/toxsci/kfg049 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

IMMUNOTOXICOLOGY:

Rajiv K. Saxena, Queen B. Saxena, David N. Weissman, Janet P. Simpson, Toni A. Bledsoe, and Daniel M. Lewis

Effect of Diesel Exhaust Particulate on Bacillus Calmette-Guerin Lung Infection in Mice and Attendant Changes in Lung Interstitial Lymphoid Subpopulations and IFN Response
ToxSci Advance Access published on April 15, 2003
Toxicol. Sci. 2003 73: 66-71; doi:10.1093/toxsci/kfg048 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

J. Zhou and G. G. Meadows

Alcohol Consumption Decreases IL-2–Induced NF-B Activity in Enriched NK Cells from C57BL/6 Mice
ToxSci Advance Access published on April 15, 2003
Toxicol. Sci. 2003 73: 72-79; doi:10.1093/toxsci/kfg047 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Neil E. Humphreys, Rebecca J. Dearman, and Ian Kimber

Assessment of Cumulative Allergen-Activated Lymph Node Cell Proliferation Using Flow Cytometry
ToxSci Advance Access published on April 15, 2003
Toxicol. Sci. 2003 73: 80-89; doi:10.1093/toxsci/kfg056 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

IN VITRO TOXICOLOGY AND ALTERNATIVE TESTING:

Jingsong Ou, Zhijun Ou, D. Gail McCarver, Ronald N. Hines, Keith T. Oldham, Allan W. Ackerman, and Kirkwood A. Pritchard, Jr.

Trichloroethylene Decreases Heat Shock Protein 90 Interactions with Endothelial Nitric Oxide Synthase: Implications for Endothelial Cell Proliferation
ToxSci Advance Access published on March 25, 2003
Toxicol. Sci. 2003 73: 90-97; doi:10.1093/toxsci/kfg062 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Vladimir Bantseev, David McCanna, Alice Banh, Winnie W. Wong, Kelley L. Moran, D. George Dixon, John R. Trevithick, and Jacob G. Sivak

Mechanisms of Ocular Toxicity Using the in Vitro Bovine Lens and Sodium Dodecyl Sulfate as a Chemical Model
ToxSci Advance Access published on April 15, 2003
Toxicol. Sci. 2003 73: 98-107; doi:10.1093/toxsci/kfg060 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

MOLECULAR AND GENETIC TOXICOLOGY:

Ludmila Yu. Zacharova, Ludmila F. Gulyaeva, Vyacheslav V. Lyakhovich, Olga N. Mikhailova, Olga A. Timofeeva, Maxim L. Filipenko, and Vasily I. Kaledin

Cytochrome P4501A1 and 1A2 Gene Expression in the Liver of 3-Methylcholanthrene- and o-Aminoazotoluene-Treated Mice: A Comparison between PAH-Responsive and PAH-Nonresponsive Strains
ToxSci Advance Access published on April 15, 2003
Toxicol. Sci. 2003 73: 108-113; doi:10.1093/toxsci/kfg053 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Farrah Clemens and Joseph R. Landolph

Genotoxicity of Samples of Nickel Refinery Dust
ToxSci Advance Access published on March 25, 2003
Toxicol. Sci. 2003 73: 114-123; doi:10.1093/toxsci/kfg070 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Laurie M. Zipper and R. Timothy Mulcahy

Erk Activation Is Required for Nrf2 Nuclear Localization during Pyrrolidine Dithiocarbamate Induction of Glutamate Cysteine Ligase Modulatory Gene Expression in HepG2 Cells
ToxSci Advance Access published on March 25, 2003
Toxicol. Sci. 2003 73: 124-134; doi:10.1093/toxsci/kfg083 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

NEUROTOXICOLOGY:

M. Farina, K. C. S. Dahm, F. D. Schwalm, A. M. Brusque, M. E. S. Frizzo, G. Zeni, D. O. Souza, and J. B. T. Rocha

Methylmercury Increases Glutamate Release from Brain Synaptosomes and Glutamate Uptake by Cortical Slices from Suckling Rat Pups: Modulatory Effect of Ebselen
ToxSci Advance Access published on April 15, 2003
Toxicol. Sci. 2003 73: 135-140; doi:10.1093/toxsci/kfg058 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

REPRODUCTIVE AND DEVELOPMENTAL TOXICOLOGY:

André Picard, Golbahar Palavan, Stéphanie Robert, Danielle Pesando, and Brigitte Ciapa

Effect of Organochlorine Pesticides on Maturation of Starfish and Mouse Oocytes
ToxSci Advance Access published on April 15, 2003
Toxicol. Sci. 2003 73: 141-148; doi:10.1093/toxsci/kfg043 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Elly Suk Hen Chow and Shuk Han Cheng

Cadmium Affects Muscle Type Development and Axon Growth in Zebrafish Embryonic Somitogenesis
ToxSci Advance Access published on April 15, 2003
Toxicol. Sci. 2003 73: 149-159; doi:10.1093/toxsci/kfg046 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Julie Lassurguère, Gabriel Livera, René Habert, and Bernard Jégou

Time- and Dose-Related Effects of Estradiol and Diethylstilbestrol on the Morphology and Function of the Fetal Rat Testis in Culture
ToxSci Advance Access published on March 25, 2003
Toxicol. Sci. 2003 73: 160-169; doi:10.1093/toxsci/kfg065 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

RESPIRATORY TOXICOLOGY:

Christopher A. Reilly, Jack L. Taylor, Diane L. Lanza, Brian A. Carr, Dennis J. Crouch, and Garold S. Yost

Capsaicinoids Cause Inflammation and Epithelial Cell Death through Activation of Vanilloid Receptors
Toxicol. Sci. 2003 73: 170-181; doi:10.1093/toxsci/kfg044 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

RISK ASSESSMENT:

Michèle Bouchard, Nathalie H. Gosselin, Robert C. Brunet, Onil Samuel, Marie-Josée Dumoulin, and Gaétan Carrier

A Toxicokinetic Model of Malathion and Its Metabolites as a Tool to Assess Human Exposure and Risk through Measurements of Urinary Biomarkers
ToxSci Advance Access published on March 25, 2003
Toxicol. Sci. 2003 73: 182-194; doi:10.1093/toxsci/kfg061 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

SYSTEM TOXICOLOGY:

Lasantha R. Bandara, Mike D. Kelly, Edward A. Lock, and Sandy Kennedy

A Correlation between a Proteomic Evaluation and Conventional Measurements in the Assessment of Renal Proximal Tubular Toxicity
ToxSci Advance Access published on March 25, 2003
Toxicol. Sci. 2003 73: 195-206; doi:10.1093/toxsci/kfg068 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

To see an article, click its [Full Text] or [PDF] link. To review many abstracts, check the boxes to the left of the titles you want, and click the 'Get All Checked Abstract(s)' button. To see one abstract at a time, click its [Abstract] link.