Toxicological Sciences

REVIEW:

Martin Van den Berg, Linda S. Birnbaum, Michael Denison, Mike De Vito, William Farland, Mark Feeley, Heidelore Fiedler, Helen Hakansson, Annika Hanberg, Laurie Haws, Martin Rose, Stephen Safe, Dieter Schrenk, Chiharu Tohyama, Angelika Tritscher, Jouko Tuomisto, Mats Tysklind, Nigel Walker, and Richard E. Peterson

The 2005 World Health Organization Reevaluation of Human and Mammalian Toxic Equivalency Factors for Dioxins and Dioxin-Like Compounds
ToxSci Advance Access published on July 7, 2006
Toxicol. Sci. 2006 93: 223-241; doi:10.1093/toxsci/kfl055 [Abstract] [Full Text] [PDF] [Request Permissions]  

BIOTRANSFORMATION AND TOXICOKINETICS:

Yazen Alnouti and Curtis D. Klaassen

Tissue Distribution and Ontogeny of Sulfotransferase Enzymes in Mice
ToxSci Advance Access published on June 28, 2006
Toxicol. Sci. 2006 93: 242-255; doi:10.1093/toxsci/kfl050 [Abstract] [Full Text] [PDF] [Request Permissions]  

Timothy R. Fennell, Susan C. J. Sumner, Rodney W. Snyder, Jason Burgess, and Marvin A. Friedman

Kinetics of Elimination of Urinary Metabolites of Acrylamide in Humans
ToxSci Advance Access published on July 26, 2006
Toxicol. Sci. 2006 93: 256-267; doi:10.1093/toxsci/kfl069 [Abstract] [Full Text] [PDF] [Request Permissions]  

ENDOCRINE TOXICOLOGY:

Fang Hu, Bibek Sharma, Sandeep Mukhi, Reynaldo Patiño, and James A. Carr

The Colloidal Thyroxine (T₄) Ring as a Novel Biomarker of Perchlorate Exposure in the African Clawed Frog Xenopus laevis
ToxSci Advance Access published on June 28, 2006
Toxicol. Sci. 2006 93: 268-277; doi:10.1093/toxsci/kfl053 [Abstract] [Full Text] [PDF] [Request Permissions]  

Helen M. Crane, Daniel B. Pickford, Thomas H. Hutchinson, and J. Anne Brown

The Effects of Methimazole on Development of the Fathead Minnow, Pimephales promelas, from Embryo to Adult
ToxSci Advance Access published on July 13, 2006
Toxicol. Sci. 2006 93: 278-285; doi:10.1093/toxsci/kfl063 [Abstract] [Full Text] [PDF] [Request Permissions]  

ENVIRONMENTAL TOXICOLOGY:

Yuonne Knöbel, Michael Glei, Anja Weise, Kerstin Osswald, Anja Schäferhenrich, Konrad Klaus Richter, Uwe Claussen, and Beatrice Louise Pool-Zobel

Uranyl Nitrilotriacetate, a Stabilized Salt of Uranium, is Genotoxic in Nontransformed Human Colon Cells and in the Human Colon Adenoma Cell Line LT97
ToxSci Advance Access published on July 13, 2006
Toxicol. Sci. 2006 93: 286-297; doi:10.1093/toxsci/kfl060 [Abstract] [Full Text] [PDF] [Request Permissions]  

Lotte N. Moens, Karlijn van der Ven, Piet Van Remortel, Jurgen Del-Favero, and Wim M. De Coen

Expression Profiling of Endocrine-Disrupting Compounds Using a Customized Cyprinus carpio cDNA Microarray
ToxSci Advance Access published on July 11, 2006
Toxicol. Sci. 2006 93: 298-310; doi:10.1093/toxsci/kfl057 [Abstract] [Full Text] [PDF] Supplementary Data [Request Permissions]  

Petra Y. Kunz, Thomas Gries, and Karl Fent

The Ultraviolet Filter 3-Benzylidene Camphor Adversely Affects Reproduction in Fathead Minnow (Pimephales promelas)
ToxSci Advance Access published on July 26, 2006
Toxicol. Sci. 2006 93: 311-321; doi:10.1093/toxsci/kfl070 [Abstract] [Full Text] [PDF] [Request Permissions]  

Xu Dong Zhou, Mary Ann Sens, Scott H. Garrett, Seema Somji, Seongmi Park, Volkan Gurel, and Donald A. Sens

Enhanced Expression of Metallothionein Isoform 3 Protein in Tumor Heterotransplants Derived from As⁺³- and Cd⁺²-Transformed Human Urothelial Cells
ToxSci Advance Access published on July 19, 2006
Toxicol. Sci. 2006 93: 322-330; doi:10.1093/toxsci/kfl065 [Abstract] [Full Text] [PDF] [Request Permissions]  

Lu Wang, Brian E. Scheffler, and Kristine L. Willett

CYP1C1 Messenger RNA Expression is Inducible by Benzo[a]pyrene in Fundulus heteroclitus Embryos and Adults
ToxSci Advance Access published on July 27, 2006
Toxicol. Sci. 2006 93: 331-340; doi:10.1093/toxsci/kfl072 [Abstract] [Full Text] [PDF] [Request Permissions]  

IN VITRO TOXICOLOGY:

Andrew J. Olaharski, Zhiying Ji, Ji-Young Woo, Sophia Lim, Alan E. Hubbard, Luoping Zhang, and Martyn T. Smith

The Histone Deacetylase Inhibitor Trichostatin A Has Genotoxic Effects in Human Lymphoblasts In Vitro
ToxSci Advance Access published on July 20, 2006
Toxicol. Sci. 2006 93: 341-347; doi:10.1093/toxsci/kfl068 [Abstract] [Full Text] [PDF] Supplementary Data [Request Permissions]  

NEUROTOXICOLOGY:

Dzhamilja Safiulina, Nadezhda Peet, Enn Seppet, Alexander Zharkovsky, and Allen Kaasik

Dehydroepiandrosterone Inhibits Complex I of the Mitochondrial Respiratory Chain and is Neurotoxic In Vitro and In Vivo at High Concentrations
ToxSci Advance Access published on July 18, 2006
Toxicol. Sci. 2006 93: 348-356; doi:10.1093/toxsci/kfl064 [Abstract] [Full Text] [PDF] [Request Permissions]  

REPRODUCTIVE AND DEVELOPMENTAL TOXICOLOGY:

Anni R. Thomsen, Kristian Almstrup, John E. Nielsen, Ilona K. Sørensen, Ole William Petersen, Henrik Leffers, and Vibeke M. Breinholt

Estrogenic Effect of Soy Isoflavones on Mammary Gland Morphogenesis and Gene Expression Profile
ToxSci Advance Access published on June 6, 2006
Toxicol. Sci. 2006 93: 357-368; doi:10.1093/toxsci/kfl029 [Abstract] [Full Text] [PDF] Supplementary Data [Request Permissions]  

Stephanie A. Lahousse, Duncan G. Wallace, Delong Liu, Kevin W. Gaido, and Kamin J. Johnson

Testicular Gene Expression Profiling following Prepubertal Rat Mono-(2-ethylhexyl) Phthalate Exposure Suggests a Common Initial Genetic Response at Fetal and Prepubertal Ages
ToxSci Advance Access published on June 29, 2006
Toxicol. Sci. 2006 93: 369-381; doi:10.1093/toxsci/kfl049 [Abstract] [Full Text] [PDF] [Request Permissions]  

Rupesh K. Gupta, Kimberly P. Miller, Janice K. Babus, and Jodi A. Flaws

Methoxychlor Inhibits Growth and Induces Atresia of Antral Follicles through an Oxidative Stress Pathway
ToxSci Advance Access published on June 28, 2006
Toxicol. Sci. 2006 93: 382-389; doi:10.1093/toxsci/kfl052 [Abstract] [Full Text] [PDF] [Request Permissions]  

RESPIRATORY TOXICOLOGY:

Kevin R. Smith, John M. Veranth, Urmila P. Kodavanti, Ann E. Aust, and Kent E. Pinkerton

Acute Pulmonary and Systemic Effects of Inhaled Coal Fly Ash in Rats: Comparison to Ambient Environmental Particles
ToxSci Advance Access published on July 13, 2006
Toxicol. Sci. 2006 93: 390-399; doi:10.1093/toxsci/kfl062 [Abstract] [Full Text] [PDF] [Request Permissions]  

Lindsay B. Wichers, William H. Rowan, III, Julianne P. Nolan, Allen D. Ledbetter, John K. McGee, Daniel L. Costa, and William P. Watkinson

Particle Deposition in Spontaneously Hypertensive Rats Exposed via Whole-Body Inhalation: Measured and Estimated Dose
ToxSci Advance Access published on July 13, 2006
Toxicol. Sci. 2006 93: 400-410; doi:10.1093/toxsci/kfl059 [Abstract] [Full Text] [PDF] [Request Permissions]  

Ryan P. Vaughan, Michael T. Szewczyk, Jr, Michael J. Lanosa, Christopher R. DeSesa, Gerald Gianutsos, and John B. Morris

Adenosine Sensory Transduction Pathways Contribute to Activation of the Sensory Irritation Response to Inspired Irritant Vapors
ToxSci Advance Access published on July 13, 2006
Toxicol. Sci. 2006 93: 411-421; doi:10.1093/toxsci/kfl061 [Abstract] [Full Text] [PDF] [Request Permissions]  

Stephan Gebel, Bernhard Gerstmayer, Peter Kuhl, Jürgen Borlak, Kris Meurrens, and Thomas Müller

The Kinetics of Transcriptomic Changes Induced by Cigarette Smoke in Rat Lungs Reveals a Specific Program of Defense, Inflammation, and Circadian Clock Gene Expression
ToxSci Advance Access published on July 26, 2006
Toxicol. Sci. 2006 93: 422-431; doi:10.1093/toxsci/kfl071 [Abstract] [Full Text] [PDF] [Request Permissions]  

RISK ASSESSMENT:

Ahmad Mirfazaelian, Kyu-Bong Kim, Sathanandam S. Anand, Hyo J. Kim, Rogelio Tornero-Velez, James V. Bruckner, and Jeffrey W. Fisher

Development of a Physiologically Based Pharmacokinetic Model for Deltamethrin in the Adult Male Sprague-Dawley Rat
ToxSci Advance Access published on July 10, 2006
Toxicol. Sci. 2006 93: 432-442; doi:10.1093/toxsci/kfl056 [Abstract] [Full Text] [PDF] Supplementary Data [Request Permissions]  

SYSTEMS TOXICOLOGY:

Cynthia V. Rider and Gerald A. LeBlanc

Atrazine Stimulates Hemoglobin Accumulation in Daphnia magna: Is it Hormonal or Hypoxic?
ToxSci Advance Access published on July 19, 2006
Toxicol. Sci. 2006 93: 443-449; doi:10.1093/toxsci/kfl067 [Abstract] [Full Text] [PDF] [Request Permissions]  

ERRATA:

ERRATA
Toxicol. Sci. 2006 93: 450; doi:10.1093/toxsci/kfl085 [Extract] [Full Text] [PDF] [Request Permissions]  

ERRATA
Toxicol. Sci. 2006 93: 450; doi:10.1093/toxsci/kfl086 [Extract] [Full Text] [PDF] [Request Permissions]  

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