Toxicological Sciences

EDITORIAL

Curtis Klaassen

In Memorium: Gabriel L. Plaa
ToxSci Advance Access published on December 7, 2009
Toxicol. Sci. 2010 113: 279-280; doi:10.1093/toxsci/kfp295 [Extract] [Full Text] [PDF] [Request Permissions]  

TOXICOLOGICAL HIGHLIGHT

Kenneth A. Voss

A New Perspective on Deoxynivalenol and Growth Suppression
ToxSci Advance Access published on November 23, 2009
Toxicol. Sci. 2010 113: 281-283; doi:10.1093/toxsci/kfp287 [Extract] [FREE Full Text] [PDF] [Request Permissions]  

REVIEW

Get checked abstract Andreas Natsch

The Nrf2-Keap1-ARE Toxicity Pathway as a Cellular Sensor for Skin Sensitizers—Functional Relevance and a Hypothesis on Innate Reactions to Skin Sensitizers
ToxSci Advance Access published on September 18, 2009
Toxicol. Sci. 2010 113: 284-292; doi:10.1093/toxsci/kfp228 [Abstract] [Full Text] [PDF] [Request Permissions]  

BIOTRANSFORMATION AND TOXICOKINETICS

Get checked abstract Emilija Makaji, Cristina S. Trambitas, Pamela Shen, Alison C. Holloway, and Denis J. Crankshaw

Effects of Cytochrome P450 Inhibitors on the Biotransformation of Fluorogenic Substrates by Adult Male Rat Liver Microsomes and cDNA-Expressed Rat Cytochrome P450 Isoforms
ToxSci Advance Access published on October 25, 2009
Toxicol. Sci. 2010 113: 293-304; doi:10.1093/toxsci/kfp255 [Abstract] [Full Text] [PDF] [Request Permissions]  

Get checked abstract Yi M. Weaver, David J. Ehresman, John L. Butenhoff, and Bruno Hagenbuch

Roles of Rat Renal Organic Anion Transporters in Transporting Perfluorinated Carboxylates with Different Chain Lengths
ToxSci Advance Access published on November 13, 2009
Toxicol. Sci. 2010 113: 305-314; doi:10.1093/toxsci/kfp275 [Abstract] [Full Text] [PDF] [Request Permissions]  

Get checked abstract Jordan N. Smith, Jun Wang, Yuehe Lin, and Charles Timchalk

Pharmacokinetics of the Chlorpyrifos Metabolite 3,5,6-Trichloro-2-Pyridinol (TCPy) in Rat Saliva
ToxSci Advance Access published on November 17, 2009
Toxicol. Sci. 2010 113: 315-325; doi:10.1093/toxsci/kfp283 [Abstract] [Full Text] [PDF] [Request Permissions]  

Get checked abstract Lena Ernstgård, Melvin Andersen, Wolfgang Dekant, Bengt Sjögren, and Gunnar Johanson

Experimental Exposure to 1,1,1,3,3-Pentafluoropropane (HFC-245fa): Uptake and Disposition in Humans
ToxSci Advance Access published on November 13, 2009
Toxicol. Sci. 2010 113: 326-336; doi:10.1093/toxsci/kfp273 [Abstract] [Full Text] [PDF] [Request Permissions]  

Get checked abstract Ans Punt, Suzanne M. Jeurissen, Marelle G. Boersma, Thierry Delatour, Gabriele Scholz, Benoît Schilter, Peter J. van Bladeren, and Ivonne M. C. M. Rietjens

Evaluation of Human Interindividual Variation in Bioactivation of Estragole Using Physiologically Based Biokinetic Modeling
ToxSci Advance Access published on November 17, 2009
Toxicol. Sci. 2010 113: 337-348; doi:10.1093/toxsci/kfp272 [Abstract] [Full Text] [PDF] [Request Permissions]  

CARCINOGENICITY

Get checked abstract Shugo Suzuki, Lora L. Arnold, Karen L. Pennington, Satoko Kakiuchi-Kiyota, Min Wei, Hideki Wanibuchi, and Samuel M. Cohen

Effects of Pioglitazone, a Peroxisome Proliferator–Activated Receptor Gamma Agonist, on the Urine and Urothelium of the Rat
ToxSci Advance Access published on October 25, 2009
Toxicol. Sci. 2010 113: 349-357; doi:10.1093/toxsci/kfp256 [Abstract] [Full Text] [PDF] [Request Permissions]  

Get checked abstract Shashikiran Donthamsetty, William Bowen, Wendy Mars, Vishakha Bhave, Jian-Hua Luo, Cary Wu, Jennifer Hurd, Ann Orr, Aaron Bell, and George Michalopoulos

Liver-Specific Ablation of Integrin-Linked Kinase in Mice Results in Enhanced and Prolonged Cell Proliferation and Hepatomegaly after Phenobarbital Administration
ToxSci Advance Access published on November 17, 2009
Toxicol. Sci. 2010 113: 358-366; doi:10.1093/toxsci/kfp281 [Abstract] [Full Text] [PDF] [Request Permissions]  

ENDOCRINE TOXICOLOGY

Get checked abstract Katie B. Paul, Joan M. Hedge, Michael J. DeVito, and Kevin M. Crofton

Short-term Exposure to Triclosan Decreases Thyroxine In Vivo via Upregulation of Hepatic Catabolism in Young Long-Evans Rats
ToxSci Advance Access published on November 12, 2009
Toxicol. Sci. 2010 113: 367-379; doi:10.1093/toxsci/kfp271 [Abstract] [Full Text] [PDF] [Supplementary Data] [Request Permissions]  

ENVIRONMENTAL TOXICOLOGY

Get checked abstract Jessica C. Hervé, Doug Crump, Stephanie P. Jones, Lukas J. Mundy, John P. Giesy, Matthew J. Zwiernik, Steven J. Bursian, Paul D. Jones, Steve B. Wiseman, Yi Wan, and Sean W. Kennedy

Cytochrome P4501A Induction by 2,3,7,8-Tetrachlorodibenzo-p-Dioxin and Two Chlorinated Dibenzofurans in Primary Hepatocyte Cultures of Three Avian Species
ToxSci Advance Access published on November 1, 2009
Toxicol. Sci. 2010 113: 380-391; doi:10.1093/toxsci/kfp270 [Abstract] [Full Text] [PDF] [Request Permissions]  

Get checked abstract Douglas J. Fort, Robert L. Rogers, Joseph W. Gorsuch, Lisa T. Navarro, Robert Peter, and James R. Plautz

Triclosan and Anuran Metamorphosis: No Effect on Thyroid-Mediated Metamorphosis in Xenopus laevis
ToxSci Advance Access published on November 16, 2009
Toxicol. Sci. 2010 113: 392-400; doi:10.1093/toxsci/kfp280 [Abstract] [Full Text] [PDF] [Request Permissions]  

GENETIC TOXICOLOGY

Get checked abstract Min Zhang, Michelle Hanna, Jia Li, Susan Butcher, Heping Dai, and Wei Xiao

Creation of a Hyperpermeable Yeast Strain to Genotoxic Agents through Combined Inactivation of PDR and CWP Genes
ToxSci Advance Access published on November 1, 2009
Toxicol. Sci. 2010 113: 401-411; doi:10.1093/toxsci/kfp267 [Abstract] [Full Text] [PDF] [Supplementary Data] [Request Permissions]  

IMMUNOTOXICOLOGY

HIGHLIGHTED ARTICLE

Get checked abstract Chidozie J. Amuzie and James J. Pestka

Suppression of Insulin-Like Growth Factor Acid-Labile Subunit Expression—A Novel Mechanism for Deoxynivalenol-Induced Growth Retardation
ToxSci Advance Access published on October 4, 2009
Toxicol. Sci. 2010 113: 412-421; doi:10.1093/toxsci/kfp225 [Abstract] [Full Text] [PDF] [Request Permissions]  

NANOTOXICOLOGY

Get checked abstract Elina M. Rossi, Lea Pylkkänen, Antti J. Koivisto, Minnamari Vippola, Keld A. Jensen, Mirella Miettinen, Kristiina Sirola, Heli Nykäsenoja, Piia Karisola, Tuula Stjernvall, Esa Vanhala, Mirja Kiilunen, Pertti Pasanen, Maija Mäkinen, Kaarle Hämeri, Jorma Joutsensaari, Timo Tuomi, Jorma Jokiniemi, Henrik Wolff, Kai Savolainen, Sampsa Matikainen, and Harri Alenius

Airway Exposure to Silica-Coated TiO₂ Nanoparticles Induces Pulmonary Neutrophilia in Mice
ToxSci Advance Access published on October 29, 2009
Toxicol. Sci. 2010 113: 422-433; doi:10.1093/toxsci/kfp254 [Abstract] [Full Text] [PDF] [Supplementary Data] [Request Permissions]  

NEUROTOXICOLOGY

Get checked abstract Ana P. Ardais, Giordano G. Viola, Marcelo S. Costa, Fernanda Nunes, Guilherme A. Behr, Fábio Klamt, José C. F. Moreira, Diogo O. Souza, João B. T. Rocha, and Lisiane O. Porciúncula

Acute Treatment with Diphenyl Diselenide Inhibits Glutamate Uptake into Rat Hippocampal Slices and Modifies Glutamate Transporters, SNAP-25, and GFAP Immunocontent
ToxSci Advance Access published on November 18, 2009
Toxicol. Sci. 2010 113: 434-443; doi:10.1093/toxsci/kfp282 [Abstract] [Full Text] [PDF] [Request Permissions]  

REPRODUCTIVE AND DEVELOPMENTAL TOXICOLOGY

Get checked abstract Echoleah S. Rufer, Timothy A. Hacker, George R. Flentke, Victoria J. Drake, Matthew J. Brody, John Lough, and Susan M. Smith

Altered Cardiac Function and Ventricular Septal Defect in Avian Embryos Exposed to Low-Dose Trichloroethylene
ToxSci Advance Access published on November 12, 2009
Toxicol. Sci. 2010 113: 444-452; doi:10.1093/toxsci/kfp269 [Abstract] [Full Text] [PDF] [Supplementary Data] [Request Permissions]  

RESPIRATORY TOXICOLOGY

Get checked abstract Melanie A. Greeley, Laura S. Van Winkle, Patricia C. Edwards, and Charles G. Plopper

Airway Trefoil Factor Expression during Naphthalene Injury and Repair
ToxSci Advance Access published on October 30, 2009
Toxicol. Sci. 2010 113: 453-467; doi:10.1093/toxsci/kfp268 [Abstract] [Full Text] [PDF] [Supplementary Data] [Request Permissions]  

RISK ASSESSMENT

Get checked abstract Torka S. Poet, Chris R. Kirman, Michael Bader, Christoph van Thriel, Michael L. Gargas, and Paul M. Hinderliter

Quantitative Risk Analysis for N-Methyl Pyrrolidone Using Physiologically Based Pharmacokinetic and Benchmark Dose Modeling
ToxSci Advance Access published on October 29, 2009
Toxicol. Sci. 2010 113: 468-482; doi:10.1093/toxsci/kfp264 [Abstract] [Full Text] [PDF] [Request Permissions]  

COVER

COVER
Toxicol. Sci. 2010 113: NP; doi:10.1093/toxsci/kfp303 [PDF] [Request Permissions]  

STANDING MATERIAL

CONTENTS
Toxicol. Sci. 2010 113: NP; doi:10.1093/toxsci/kfp302 [PDF] [Request Permissions]  

Editorial Board
Toxicol. Sci. 2010 113: NP; doi:10.1093/toxsci/kfp304 [PDF] [Request Permissions]  

SUBSCRIPTIONS
Toxicol. Sci. 2010 113: NP; doi:10.1093/toxsci/kfp305 [PDF] [Request Permissions]  

To see an article, click its [Full Text] or [PDF] link. To review many abstracts, check the boxes to the left of the titles you want, and click the 'Get All Checked Abstract(s)' button. To see one abstract at a time, click its [Abstract] link.