Skip Navigation

ToxSci Advance Access

ToxSci Advance Access articles are papers in manuscript form that have been accepted by the journal but have not been copyedited or formatted for publication. Copyediting may lead to minor differences between the Advance Access version and the final version of the paper; there may also be differences in the quality of the graphics. More information, including how to cite Advance Access papers, can be found on the Advance Access page.

Advance Access Articles By Category [View by Date]

Go to section ENDOCRINE TOXICOLOGYENDOCRINE TOXICOLOGY
Go to section LETTERS TO THE EDITORLETTERS TO THE EDITOR
Go to section RESEARCH ARTICLERESEARCH ARTICLE
Go to section IMMUNOTOXICOLOGYIMMUNOTOXICOLOGY
Go to section SYSTEMS TOXICOLOGYSYSTEMS TOXICOLOGY
Go to section SAFETY ASSESSMENTSAFETY ASSESSMENT
Go to section IN VITRO TOXICOLOGY AND ALTERNATIVE TESTINGIN VITRO TOXICOLOGY AND ALTERNATIVE TESTING
Go to section BIOTRANSFORMATION AND TOXICOKINETICSBIOTRANSFORMATION AND TOXICOKINETICS
Go to section REPRODUCTIVE AND DEVELOPMENT TOXICOLOGYREPRODUCTIVE AND DEVELOPMENT TOXICOLOGY
Go to section TOXICOLOGICAL HIGHLIGHTTOXICOLOGICAL HIGHLIGHT
Go to section CARCINOGENICITYCARCINOGENICITY
Go to section REVIEWREVIEW
Go to section ENVIRONMENTAL TOXICOLOGYENVIRONMENTAL TOXICOLOGY
Go to section NEUROTOXICOLOGYNEUROTOXICOLOGY
Go to section RESPIRATORY TOXICOLOGYRESPIRATORY TOXICOLOGY
Go to section REPRODUCTIVE AND DEVELOPMENTAL TOXICOLOGYREPRODUCTIVE AND DEVELOPMENTAL TOXICOLOGY
Go to section RISK ASSESSMENTRISK ASSESSMENT
Go to section ARTICLEARTICLE
Go to section GENETIC TOXICOLOGYGENETIC TOXICOLOGY

To see an accepted manuscript, click its [Accepted Manuscript] link. To review many abstracts, check the boxes to the left of the titles you want, and click the 'Get All Checked Abstract(s)' button. To see one abstract at a time, click its [Abstract] link.

ENDOCRINE TOXICOLOGYGo to top of the page

Endocrine Toxicology
Juan Pablo Prestifilippo, Javier Fernández-Solari, Andrea De Laurentiis, Claudia Ester Mohn, Carolina de la Cal, Roxana Reynoso, W. Les Dees, and Valeria Rettori
Acute effect of manganese on hypothalamic luteinizing hormone releasing hormone (LHRH) secretion in adult male rats: Involvement of specific neurotransmitter systems
ToxSci Advance Access published on July 4, 2008.
doi:10.1093/toxsci/kfn135
[Abstract] [Accepted Manuscript] [Request Permissions]  

LETTERS TO THE EDITORGo to top of the page

LETTERS TO THE EDITOR
Daniel L. Morgan PhD, Gordon P. Flake MD, Patrick J. Kirby PhD, and Scott M. Palmer MD, MHS
Response to: Comments on Respiratory Toxicity of Diacetyl in C57Bl/6 Mice
ToxSci Advance Access published on July 3, 2008.
doi:10.1093/toxsci/kfn134
[Accepted Manuscript] [Request Permissions]  

LETTERS TO THE EDITOR
Brent L. Finley, David A. Galbraith MD, and David Weill MD
Comments on Respiratory Toxicity of Diacetyl: RE: Morgan DL, Flake GP, Kirby PJ, and Palmer SM (2008). Respiratory toxicity of diacetyl in C57Bl/6 mice. Toxicol Sci, 103(1), 169–180.
ToxSci Advance Access published on July 3, 2008.
doi:10.1093/toxsci/kfn133
[Accepted Manuscript] [Request Permissions]  

RESEARCH ARTICLEGo to top of the page

Research Article
Cláudia V. Pereira, Nuno G. Machado, and Paulo J. Oliveira
Mechanisms of Berberine [Natural Yellow 18, 5,6-dihydro-9,10-dimethoxybenzo(g)-1,3-benzodioxolo (5,6-a) quinolizinium]-induced Mitochondrial Dysfunction: Interaction with the Adenine Nucleotide Translocator
ToxSci Advance Access published on July 3, 2008.
doi:10.1093/toxsci/kfn131
[Abstract] [Accepted Manuscript] [Request Permissions]  

IMMUNOTOXICOLOGYGo to top of the page

Immunotoxicology
Jennifer S. Gray, Hee Kyong Bae, C. B. Li James, Alan S. Lau, and James J. Pestka
Double-Stranded RNA-Activated Protein Kinase (PKR) Mediates Induction of IL-8 Expression by Deoxynivalenol, Shiga Toxin 1 and Ricin in Monocytes
ToxSci Advance Access published on July 3, 2008.
doi:10.1093/toxsci/kfn128
[Abstract] [Accepted Manuscript] [Request Permissions]  

Immunotoxicology
Xuemei Fang, Lianjun Zhang, Yixing Feng, Yong Zhao, and Jiayin Dai
Immunotoxic Effects of Perfluorononanoic Acid on BALB/c Mice
ToxSci Advance Access published on June 26, 2008.
doi:10.1093/toxsci/kfn127
[Abstract] [Accepted Manuscript] [Request Permissions]  

Immunotoxicology
Scott E. Loveless, Denise Hoban, Greg Sykes, Steven R. Frame, and Nancy E. Everds
Evaluation of the Immune System in Rats and Mice Administered Linear Ammonium Perfluorooctanoate (APFO)
ToxSci Advance Access published on June 16, 2008.
doi:10.1093/toxsci/kfn113
[Abstract] [Accepted Manuscript] [Request Permissions]  

Immunotoxicology
Darrell R. Boverhof, Connie M. Wiescinski, Phil Botham, David Lees, Eric Debruyne, Marina Repetto-Larsay, Gregory Ladics, Denise Hoban, Armin Gamer, Marina Remmele, Weizheng Wang-Fan, Ludwig G. Ullmann, Jyotigna Mehta, Richard Billington, and Michael R. Woolhiser
Interlaboratory validation of 1% Pluronic® L92 surfactant as a suitable, aqueous vehicle for testing pesticide formulations using the murine local lymph node assay
ToxSci Advance Access published on June 12, 2008.
doi:10.1093/toxsci/kfn117
[Accepted Manuscript] [Request Permissions]  

Immunotoxicology
Maoxiang Li and James J. Pestka
Comparative Induction of 28S Ribosomal RNA Cleavage by Ricin and the Trichothecenes Deoxynivalenol and T-2 Toxin in the Macrophage
ToxSci Advance Access published on June 4, 2008.
doi:10.1093/toxsci/kfn111
[Abstract] [Accepted Manuscript] [Request Permissions]  

Immunotoxicology
Hee Kyong Bae and James J. Pestka
Deoxynivalenol Induces p38 Interaction with the Ribosome in Monocytes and Macrophages
ToxSci Advance Access published on May 22, 2008.
doi:10.1093/toxsci/kfn102
[Abstract] [Accepted Manuscript] [Request Permissions]  

IMMUNOTOXICOLOGY
Jürgen Pauluhn
BROWN NORWAY RAT ASTHMA MODEL OF DIPHENYLMETHANE-4,4'-DIISOCYANATE (MDI): ANALYSIS OF THE ELICITATION DOSE-RESPONSE RELATIONSHIP.
ToxSci Advance Access published on May 20, 2008.
doi:10.1093/toxsci/kfn098
[Abstract] [Accepted Manuscript] [Request Permissions]  

Immunotoxicology
Margaret M. Whalen, Jamie C. DeWitt, and Robert W. Luebke
Serum supplementation modulates the effects of dibutyltin on human natural killer cell function
ToxSci Advance Access published on April 25, 2008.
doi:10.1093/toxsci/kfn082
[Abstract] [Accepted Manuscript] [Request Permissions]  

SYSTEMS TOXICOLOGYGo to top of the page

Systems Toxicology
Alexandra Vranyac-Tramoundanas, Joanne C. Harrison, Andrew N. Clarkson, Mohit Kapoor, Ian C. Winburn, D. Steven Kerr, and Ivan A. Sammut
Domoic acid impairment of cardiac energetics
ToxSci Advance Access published on July 1, 2008.
doi:10.1093/toxsci/kfn132
[Abstract] [Accepted Manuscript] [Request Permissions]  

SYSTEMS TOXICOLOGY
Monicah A. Otieno, Nicole Bavuso, Joseph Milano, Linda-Foster Brown, Khanh-Hui Bui, Yan Li, Thomas Hudzik, Debra Wescott, Calvert Louden, Martin Dyroff, and François Pognan
Mechanistic Investigation of N,N-diethyl-4-(phenyl-piperidin-4-ylidenemethyl)-benzamide -induced Insulin depletion in the rat and RINm5F Cells.
ToxSci Advance Access published on June 6, 2008.
doi:10.1093/toxsci/kfn108
[Abstract] [Accepted Manuscript] [Request Permissions]  

Systems Toxicology
Christy C. Bridges, Lucy Joshee, and Rudolfs K. Zalups
MRP2 and the DMPS- and DMSA-Mediated Elimination of Mercury in TR– and Control Rats Exposed to Thiol S-conjugates of Inorganic Mercury
ToxSci Advance Access published on May 28, 2008.
doi:10.1093/toxsci/kfn107
[Abstract] [Accepted Manuscript] [Request Permissions]  

Systems Toxicology
Mary Lynn Bajt, Hui-Min Yan, Anwar Farhood, and Hartmut Jaeschke
PLASMINOGEN ACTIVATOR INHIBITOR-1 LIMITS LIVER INJURY AND FACILITATES REGENERATION AFTER ACETAMINOPHEN OVERDOSE
ToxSci Advance Access published on May 9, 2008.
doi:10.1093/toxsci/kfn091
[Abstract] [Accepted Manuscript] [Request Permissions]  

Systems Toxicology
L.D. Burgoon and T.R. Zacharewski
Automated Quantitative Dose Response Modeling and Point of Departure Determination for Large Toxicogenomic and High Throughput Screening Datasets
ToxSci Advance Access published on April 25, 2008.
doi:10.1093/toxsci/kfn083
[Abstract] [Accepted Manuscript] [Supplementary Data] [Request Permissions]  

SAFETY ASSESSMENTGo to top of the page

Safety Assessment
Brenda Faiola, J Greg Falls, Richard A Peterson, Nancy R Bordelon, Thomas A Brodie, Connie A Cummings, Elizabeth H Romach, and Richard T Miller
PPAR alpha, more than PPAR delta, mediates the hepatic and skeletal muscle alterations induced by the PPAR agonist GW0742
ToxSci Advance Access published on June 30, 2008.
doi:10.1093/toxsci/kfn130
[Abstract] [Accepted Manuscript] [Request Permissions]  

Safety Assessment
M. Carbonatto, P. Yu, M. Bertolino, E. Vigna, S. Steidler, L. Fava, C. Daghero, B. Roattino, M. Onidi, M. Ardizzone, S. Peano, J. Visich, D. Janszen, S. R. Dillon, and R. A. Ponce
Nonclinical Safety, Pharmacokinetics, and Pharmacodynamics of Atacicept
ToxSci Advance Access published on June 2, 2008.
doi:10.1093/toxsci/kfn105
[Abstract] [Accepted Manuscript] [Supplementary Data] [Request Permissions]  

IN VITRO TOXICOLOGY AND ALTERNATIVE TESTINGGo to top of the page

In Vitro Toxicology and Alternative Testing
Annelieke K. Peters, Margino Steemans, Erik Hansen, Natalie Mesens, Geert R. Verheyen, and Philippe Vanparys
Evaluation of the embryotoxic potency of compounds in a newly revised high throughput embryonic stem cell test
ToxSci Advance Access published on June 30, 2008.
doi:10.1093/toxsci/kfn126
[Abstract] [Accepted Manuscript] [Request Permissions]  

In Vitro Toxicology and Alternative Testing
Joseph M. Breier, Nicholas M. Radio, William R. Mundy, and Timothy J. Shafer
Development of a high-throughput screening assay for chemical effects on proliferation and viability of immortalized human neural progenitor cells
ToxSci Advance Access published on June 11, 2008.
doi:10.1093/toxsci/kfn115
[Abstract] [Accepted Manuscript] [Request Permissions]  

In Vitro Toxicology and Alternative Testing
Nicholas M. Radio, Joseph M. Breier, Timothy J. Shafer&, and William R. Mundy
Assessment of chemical effects on neurite outgrowth in PC12 cells using high content screening
ToxSci Advance Access published on June 6, 2008.
doi:10.1093/toxsci/kfn114
[Abstract] [Accepted Manuscript] [Request Permissions]  

In Vitro Toxicology and Alternative Testing
Jinghai J. Xu, Peter V. Henstock, Margaret C. Dunn, Arthur R. Smith, Jeffrey R. Chabot, and David de Graaf
Cellular Imaging Predictions of Clinical Drug-Induced Liver Injury
ToxSci Advance Access published on June 3, 2008.
doi:10.1093/toxsci/kfn109
[Abstract] [Accepted Manuscript] [Supplementary Data] [Request Permissions]  

BIOTRANSFORMATION AND TOXICOKINETICSGo to top of the page

Biotransformation and Toxicokinetics
T. S. McMullin, E. R. Lowe, M. J. Bartels, and M.S. Marty
Dynamic changes in lipids and proteins of maternal, fetal and pup blood and milk during perinatal development in CD and Wistar rats
ToxSci Advance Access published on June 30, 2008.
doi:10.1093/toxsci/kfn124
[Abstract] [Accepted Manuscript] [Supplementary Data] [Request Permissions]  

Biotransformation and Toxicokinetics
Micaela B. Reddy, Ivan D. Dobrev, Debra A. McNett, Joseph M. Tobin, Mark J. Utell, Paul E. Morrow, Jean Y. Domoradzki, Kathleen P. Plotzke, and Melvin E. Andersen
Inhalation Dosimetry Modeling with Inhaled Decamethylcyclopentasiloxane in Rats and Humans
ToxSci Advance Access published on June 26, 2008.
doi:10.1093/toxsci/kfn125
[Abstract] [Accepted Manuscript] [Supplementary Data] [Request Permissions]  

BIOTRANSFORMATION AND TOXICOKINETICS
Matthew Zwiernik, Steven Bursian, Lesa L. Aylward, Denise Kay, Jeremy Moore, J. Craig Rowlands, Kent Woodburn, Melissa Shotwell, Jong Seong Khim, John P. Giesy, and Robert A. Budinsky
Toxicokinetics of 2,3,7,8-TCDF AND 2,3,4,7,8-PECDF in Mink (Mustela vison) at Ecologically Relevant Exposures
ToxSci Advance Access published on June 19, 2008.
doi:10.1093/toxsci/kfn118
[Abstract] [Accepted Manuscript] [Supplementary Data] [Request Permissions]  

Biotransformation and Toxicokinetics
Lauren M Aleksunes, Sarah N Campion, Michael J Goedken, and José E Manautou
Acquired Resistance to Acetaminophen Hepatotoxicity is Associated with Induction of Multidrug Resistance-Associated Protein 4 (Mrp4) in Proliferating Hepatocytes
ToxSci Advance Access published on May 8, 2008.
doi:10.1093/toxsci/kfn093
[Abstract] [Accepted Manuscript] [Supplementary Data] [Request Permissions]  

BIOTRANSFORMATION AND TOXICOKINETICS
Marina V. Evans, Sean M. Dowd, Elaina M. Kenyon, Michael F. Hughes, and Hisham A. El-Masri
A PHYSIOLOGICALLY BASED PHARMACOKINETIC MODEL FOR INTRAVENOUS AND INGESTED DIMETHYLARSINIC ACID (DMAV) IN MICE.
ToxSci Advance Access published on May 5, 2008.
doi:10.1093/toxsci/kfn080
[Abstract] [Accepted Manuscript] [Supplementary Data] [Request Permissions]  

REPRODUCTIVE AND DEVELOPMENT TOXICOLOGYGo to top of the page

Reproductive and Development Toxicology
Sheller Zabihi, Parri Wentzel, and Ulf J. Eriksson
Maternal blood glucose levels determine the severity of diabetic embryopathy in mice with different expression of copper-zinc superoxide dismutase (CuZnSOD)
ToxSci Advance Access published on June 26, 2008.
doi:10.1093/toxsci/kfn101
[Abstract] [Accepted Manuscript] [Request Permissions]  

TOXICOLOGICAL HIGHLIGHTGo to top of the page

TOXICOLOGICAL HIGHLIGHT
Richard M Sharpe
‘Additional’ effects of phthalate mixtures on fetal testosterone production
ToxSci Advance Access published on June 25, 2008.
doi:10.1093/toxsci/kfn123
[Accepted Manuscript] [Request Permissions]  

CARCINOGENICITYGo to top of the page

Carcinogenicity
Lanlan Zhou, Yiguo Jiang, Aijun Tan, Anne R Greenlee, Yuelan Shen, Linhua Liu, and Qiaoyuan Yang
Silencing of N-Ras Gene Expression Using shRNA Decreases Transformation Efficiency and Tumor Growth in Transformed Cells Induced by Anti-BPDE
ToxSci Advance Access published on June 20, 2008.
doi:10.1093/toxsci/kfn122
[Abstract] [Accepted Manuscript] [Request Permissions]  

Carcinogenicity
Jie Liu and Michael P. Waalkes
Liver is a target of arsenic carcinogenesis
ToxSci Advance Access published on June 19, 2008.
doi:10.1093/toxsci/kfn120
[Abstract] [Accepted Manuscript] [Request Permissions]  

Carcinogenicity
Christine M. Hegedus, Christine F. Skibola, Marcella Warner, Danica R. Skibola, David Alexander, Sophia Lim, Nygerma Dangleben, Luoping Zhang, Michael Clark, Ruth M. Pfeiffer, Craig Steinmaus, Allan H. Smith, Martyn T. Smith, and Lee E. Moore
Decreased Urinary Beta Defensin-1 Expression as a Biomarker of Response to Arsenic
ToxSci Advance Access published on May 28, 2008.
doi:10.1093/toxsci/kfn104
[Abstract] [Accepted Manuscript] [Supplementary Data] [Request Permissions]  

Carcinogenicity
Chia-Chi Ho, Yong-Chien Ling, Louis W. Chang, Hui-Ti Tsai, Ming-Hsien Tsai, and Pinpin Lin
17 beta Estradiol and Hydroxyestradiols Interact Via the NF-Kappa B Pathway To Elevate Cyclo-oxygenase 2 Expression and Prostaglandin E2 Secretion in Human Bronchial Epithelial Cells.
ToxSci Advance Access published on May 13, 2008.
doi:10.1093/toxsci/kfn096
[Abstract] [Accepted Manuscript] [Request Permissions]  

Carcinogenicity
Rong-Jane Chen, Yuan-Soon Ho, How-Ran Guo, and Ying-Jan Wang
Rapid Activation of Stat3 and ERK1/2 by Nicotine Modulates Cell Proliferation in Human Bladder Cancer Cells
ToxSci Advance Access published on April 30, 2008.
doi:10.1093/toxsci/kfn086
[Abstract] [Accepted Manuscript] [Supplementary Data] [Request Permissions]  

Carcinogenicity
Yuichi Kuroiwa, Masami Yamada, Keiko Matsui, Toshiya Okamura, Yuji Ishii, Ken-ichi Masumura, Masako Tasaki, Takashi Umemura, Kunitoshi Mitsumori, Takehiko Nohmi, Masao Hirose, and Akiyoshi Nishikawa
Combined ascorbic acid and sodium nitrite treatment induces oxidative DNA damage associated mutagenicity in vitro, but lacks initiation activity in rat forestomach epithelium
ToxSci Advance Access published on April 22, 2008.
doi:10.1093/toxsci/kfn081
[Abstract] [Accepted Manuscript] [Request Permissions]  

REVIEWGo to top of the page

Review
Maxwell C. K. Leung, Phillip L. Williams, Alexandre Benedetto, Catherine Au, Kirsten J. Helmcke, Michael Aschner, and Joel N. Meyer
Caenorhabditis elegans: an Emerging Model in Biomedical and Environmental Toxicology
ToxSci Advance Access published on June 19, 2008.
doi:10.1093/toxsci/kfn121
[Abstract] [Accepted Manuscript] [Supplementary Data]     OPEN ACCESS ARTICLE

Review
A. K. Hotckiss, C. V. Rider, C. R. Blystone, V. S. Wilson, P. C. Hartig, G. T. Ankley, P. M. Foster, C. L. Gray, and L. E. Gray
Fifteen years after "Wingspread"- Environmental Endocrine Disrupters and human and wildlife health: Where we are today and where we need to go.
ToxSci Advance Access published on February 16, 2008.
doi:10.1093/toxsci/kfn030
[Abstract] [Accepted Manuscript] [Request Permissions]  

Review
Sonya M. Billiard, Joel N. Meyer, Deena M. Wassenberg, Peter V. Hodson, and Richard T. Di Giulio
Non-additive effects of PAHs on early vertebrate development: mechanisms and implications for risk assessment.
ToxSci Advance Access published on December 20, 2007.
doi:10.1093/toxsci/kfm303
[Abstract] [Accepted Manuscript] [Request Permissions]  

Review
Richard M. LoPachin, David S. Barber, and Terrence Gavin
MOLECULAR MECHANISMS OF THE CONJUGATED {alpha},β–UNSATURATED CARBONYL DERIVATIVES: RELEVANCE TO NEUROTOXICITY AND NEURODEGENERATIVE DISEASES
ToxSci Advance Access published on December 13, 2007.
doi:10.1093/toxsci/kfm301
[Abstract] [Accepted Manuscript] [Request Permissions]  

ENVIRONMENTAL TOXICOLOGYGo to top of the page

Environmental Toxicology
Bibek Sharma and Reynaldo Patiño
Exposure of Xenopus laevis Tadpoles to Cadmium Reveals Concentration-dependent Bimodal Effects on Growth and Monotonic Effects on Development and Thyroid Gland Activity
ToxSci Advance Access published on June 14, 2008.
doi:10.1093/toxsci/kfn119
[Abstract] [Accepted Manuscript] [Request Permissions]  

Environmental Toxicology
Min He, Jiyang Cai, Young-Mi Go, Jennifer M. Johnson, W. David Martin, Jason M. Hansen, and Dean P. Jones
Identification of thioredoxin-2 as a regulator of the mitochondrial permeability transition
ToxSci Advance Access published on June 11, 2008.
doi:10.1093/toxsci/kfn116
[Abstract] [Accepted Manuscript] [Request Permissions]  

Environmental Toxicology
Vatsal Mehta, Richard E. Peterson, and Warren Heideman
2,3,7,8-Tetrachlorodibenzo-p-dioxin Exposure Prevents Cardiac Valve Formation in Developing Zebrafish
ToxSci Advance Access published on May 13, 2008.
doi:10.1093/toxsci/kfn095
[Abstract] [Accepted Manuscript] [Supplementary Data]     OPEN ACCESS ARTICLE

NEUROTOXICOLOGYGo to top of the page

Neurotoxicology
Zahidul Islam, Colleen C. Hegg, and James J. Pestka
Satratoxin G-Induced Apoptosis in PC-12 Neuronal Cells is Mediated by PKR and Caspase-Independent
ToxSci Advance Access published on June 4, 2008.
doi:10.1093/toxsci/kfn110
[Abstract] [Accepted Manuscript] [Request Permissions]  

Neurotoxicology
Tshala-Katumbay Desire, Monterroso Victor, Kayton Robert, Lasarev Michael, Sabri Mohammad, and Spencer Peter
Probing mechanisms of axonopathy. Part I: Protein targets of 1,2-diacetylbenzene, the neurotoxic metabolite of aromatic solvent 1,2-diethylbenzene.
ToxSci Advance Access published on May 22, 2008.
doi:10.1093/toxsci/kfn103
[Abstract] [Accepted Manuscript] [Request Permissions]  

Neurotoxicology
Monica Sanchez, Laura Gastaldi, Monica Remedi, Alfredo Cáceres, and Carlos Landa
Rotenone-induced toxicity is mediated by Rho-GTPases in hippocampal neurons
ToxSci Advance Access published on May 13, 2008.
doi:10.1093/toxsci/kfn092
[Abstract] [Accepted Manuscript] [Supplementary Data] [Request Permissions]  

NEUROTOXICOLOGY
C. Konjuh, G. García, LM. López, AM. Evangelista de Duffard, A. Brusco, and R. Duffard
Neonatal hypomyelination by the herbicide 2,4-dichlorophenoxyacetic acid. Chemical and ultrastructural studies in rats.
ToxSci Advance Access published on May 5, 2008.
doi:10.1093/toxsci/kfn085
[Abstract] [Accepted Manuscript] [Request Permissions]  

Neurotoxicology
Ke Yu, Yuhe He, Leo W. Y. Yeung, Paul K.S. Lam, Rudolf S.S. Wu, and Bingsheng Zhou
DE-71-induced apoptosis involving intracellular calcium and the Bax-mitochondria-caspase protease pathway in human neuroblastoma cells in vitro
ToxSci Advance Access published on May 2, 2008.
doi:10.1093/toxsci/kfn088
[Abstract] [Accepted Manuscript] [Request Permissions]  

RESPIRATORY TOXICOLOGYGo to top of the page

Respiratory Toxicology
Michael T. Borchers, Scott C. Wesselkamper, Bryan L. Eppert, Gregory T. Motz, Maureen A. Sartor, Craig R. Tomlinson, Mario Medvedovic, and Jay W. Tichelaar
Non-Redundant Functions of {alpha}β and {gamma}{delta} T Cells in Acrolein-Induced Pulmonary Pathology
ToxSci Advance Access published on May 29, 2008.
doi:10.1093/toxsci/kfn106
[Abstract] [Accepted Manuscript] [Request Permissions]  

REPRODUCTIVE AND DEVELOPMENTAL TOXICOLOGYGo to top of the page

Reproductive and Developmental Toxicology
Kaberi P. Das, Brian E. Grey, Robert D. Zehr, Carmen R. Wood, John L. Butenhoff, Shu-Ching Chang, David J. Ehresman, Yu-Mei Tan, and Christopher Lau
Effects of perfluorobutyrate exposure during pregnancy in the mouse
ToxSci Advance Access published on May 28, 2008.
doi:10.1093/toxsci/kfn099
[Abstract] [Accepted Manuscript] [Request Permissions]  

Reproductive and Developmental Toxicology
Daniel A. Symonds, Istvan Merchenthaler, and Jodi A. Flaws
Methoxychlor and Estradiol Induce Oxidative Stress DNA Damage in the Mouse Ovarian Surface Epithelium
ToxSci Advance Access published on May 22, 2008.
doi:10.1093/toxsci/kfn100
[Abstract] [Accepted Manuscript] [Request Permissions]  

Reproductive and Developmental Toxicology
Francesca Di Renzo, Graziella Cappelletti, Maria Luisa Broccia, Erminio Giavini, and Elena Menegola
The inhibition of embryonic histone deacetylases as the possible mechanism accounting for axial skeletal malformations induced by Sodium Salicylate.
ToxSci Advance Access published on May 14, 2008.
doi:10.1093/toxsci/kfn094
[Abstract] [Accepted Manuscript] [Request Permissions]  

Reproductive and Developmental Toxicology
Xiaozhong Yu, S Hong, and Elaine M. Faustman
Cadmium-induced activation of stress signaling pathways, disruption of ubiquitin-dependent protein degradation and apoptosis in primary rat Sertoli cell-gonocyte co-cultures
ToxSci Advance Access published on May 6, 2008.
doi:10.1093/toxsci/kfn087
[Abstract] [Accepted Manuscript] [Request Permissions]  

Reproductive and Developmental Toxicology
Rochelle W. Tyl, Christina B. Myers, Melissa C. Marr, Carol S. Sloan, Nora P. Castillo, M. Michael Veselica, John C. Seely, Stephen S. Dimond, John P. Van Miller, Ronald N. Shiotsuka, Dieter Beyer, Steven G. Hentges, and John M. Waechter Jr.
Two-Generation Reproductive Toxicity Study of Dietary Bisphenol A (BPA) in CD-1 (Swiss) Mice
ToxSci Advance Access published on May 6, 2008.
doi:10.1093/toxsci/kfn084
[Abstract] [Accepted Manuscript] [Supplementary Data] [Request Permissions]  

Reproductive and Developmental Toxicology
Kembra L. Howdeshell, Vickie S. Wilson, Johnathan Furr, Christy R. Lambright, Cynthia V. Rider, Chad R. Blystone, Andrew K. Hotchkiss, and Leon Earl Gray Jr
A mixture of five phthalate esters inhibits fetal testicular testosterone production in the Sprague Dawley rat in a cumulative, dose additive manner
ToxSci Advance Access published on April 14, 2008.
doi:10.1093/toxsci/kfn077
[Abstract] [Accepted Manuscript] [Supplementary Data] [Request Permissions]  

RISK ASSESSMENTGo to top of the page

Risk Assessment
Melvin E. Andersen, Harvey J. Clewell III, Edilberto Bermudez, Gabrielle A. Willson, and Russell S. Thomas
Genomic Signatures and Dose Dependent Transitions in Nasal Epithelial Responses to Inhaled Formaldehyde in the Rat
ToxSci Advance Access published on May 21, 2008.
doi:10.1093/toxsci/kfn097
[Abstract] [Accepted Manuscript] [Supplementary Data] [Request Permissions]  

ARTICLEGo to top of the page

Article
Maureen Mongan, Zongqing Tan, Liang Chen, Zhimin Peng, Maggie Dietsch, Bing Su, George Leikauf, and Ying Xia
Mitogen-activated protein kinase kinase kinase 1 protects against nickel-induced acute lung injury
ToxSci Advance Access published on May 7, 2008.
doi:10.1093/toxsci/kfn089
[Abstract] [Accepted Manuscript] [Supplementary Data] [Request Permissions]  

GENETIC TOXICOLOGYGo to top of the page

To see an accepted manuscript, click its [Accepted Manuscript] link. To review many abstracts, check the boxes to the left of the titles you want, and click the 'Get All Checked Abstract(s)' button. To see one abstract at a time, click its [Abstract] link.